Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Orthocresol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orthocresol SCHEMBL27997772 | 1.00 | TRPA1 (0.57) | — | |
| Orthocresol SCHEMBL11178411 | 1.00 | TRPA1 (0.57) | — | |
| Orthocresol SCHEMBL5481807 | 1.00 | — | — | |
| Orthocresol SCHEMBL11568473 | 0.97 | TRPA1 (0.55) | — | |
| Orthocresol SCHEMBL11781053 | 0.97 | TRPA1 (0.55) | — | |
| Orthocresol SCHEMBL27566228 | 0.97 | TRPA1 (0.55) | — | |
| Orthocresol SCHEMBL6039936 | 0.97 | TRPA1 (0.55) | — | |
| Orthocresol SCHEMBL29395276 | 0.97 | — | — | |
| Orthocresol SCHEMBL16002 | 0.97 | — | — | |
| Orthocresol SCHEMBL10419161 | 0.97 | TRPA1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106742373-B | A kind of automatic charging packaging facilities and its working method based on the exploitation of functional gingko milk beverage | 徐州工程学院 | 2019-03-15 | — | — | CN | claimed |
| CN-106742373-A | A kind of automatic charging packaging facilities and its method of work based on the exploitation of feature gingko milk beverage | 徐州工程学院 | 2017-05-31 | — | — | CN | claimed |
| CN-104004141-A | Polymer monolithic column and preparation method thereof as well as application of polymer monolithic column in preparation of enzyme reactor | CHINESE ACAD INST CHEMISTRY | 2014-08-27 | — | — | CN | claimed |
| CN-101602734-B | Method for preparing Erlotinib hydrochloride crystal form A | ZHEJIANG JIUZHOU PHARM CO LTD | 2011-07-20 | — | — | CN | claimed |
| CN-101602734-A | A kind of preparation method of Erlotinib hydrochloride crystal form A | ZHEJIANG JIUZHOU PHARMACEUTICA (CN) | 2009-12-16 | — | — | CN | claimed |
| CN-1473931-A | Novel fermented soya beans streptokinase, its producing method and microbe for producing said streptokinase | 四川大学 | 2004-02-11 | — | — | CN | claimed |
| CN-118542949-A | Delivery system for functional nucleases | 哈佛大学的校长及成员们 | 2024-08-27 | — | — | CN | disclosed |
| CN-115605471-A | Heterocyclic compound and organic light-emitting device comprising same | 株式会社LG化学（KR） | 2023-01-13 | — | — | CN | disclosed |
| CN-115297863-A | Topical pharmaceutical compositions comprising imidazo [1,2-b ] pyridazine compounds | 博善人工智能生物科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-110581232-B | Preparation method of OLED (organic light emitting diode) light emitting device, OLED light emitting device and OLED display device | 合肥京东方卓印科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-11342393-B2 | Method for manufacturing OLED light emitting device, OLED light emitting device and OLED display device | HEFEI BOE JOINT TECHNOLOGY CO., LTD. (CN) | 2022-05-24 | — | — | US | disclosed |
| US-20210091150-A1 | METHOD FOR MANUFACTURING OLED LIGHT EMITTING DEVICE, OLED LIGHT EMITTING DEVICE AND OLED DISPLAY DEVICE | HEFEI BOE JOINT TECHNOLOGY CO., LTD. (CN) | 2021-03-25 | — | — | US | disclosed |
| CN-110581232-A | Preparation method of OLED (organic light emitting diode) light emitting device, OLED light emitting device and OLED display device | 合肥京东方卓印科技有限公司 | 2019-12-17 | — | — | CN | disclosed |
| CN-1235572-C | Adhesive preparations | HISAMITSU PHARMACEUTICAL CO (JP) | 2006-01-11 | — | — | CN | disclosed |
| US-6727081-B2 | ISOLATED MICROORGANISM FOR USE IN THE GENERATION OF ANTICARCINOGENIC AGENTS, IMMUNOMODULATORS AND ANIMAL NUTRIENTS | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2004-04-27 | — | — | US | disclosed |
| US-20030109819-A1 | Adhesive preparations | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2003-06-12 | — | — | US | disclosed |
| CN-1409628-A | Patch preparation | HISAMITSU PHARMACEUTICAL CO (JP) | 2003-04-09 | — | — | CN | disclosed |
| US-20030008984-A1 | Novel catalyst system and the use thereof | BASELL POLYOLEFINE GMBH (DE) | 2003-01-09 | — | — | US | disclosed |
| EP-1238664-A1 | ADHESIVE PREPARATIONS | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-20020115158-A1 | Novel microorganism isolated from chinese elm (Ulmus sp.) and process for preparing exopolysaccharides by employing the microorganism | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2002-08-22 | — | — | US | disclosed |