Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.79 |
| ▸ | TOP1 known ✓ | P11387 | 3/20 | 0.62 |
| ▸ | TOP2A known ✓ | P11388 | 3/20 | 0.62 |
| ▸ | DRD3 known ✓ | P35462 | 5/20 | 0.51 |
| ▸ | DRD2 known ✓ | P14416 | 4/20 | 0.50 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.48 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.48 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | BLM | P54132 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.79 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29728780 | 1.00 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MAPTMEN1BLM | |
| Hydrochloric Acid SCHEMBL659782 | 1.00 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MAPTMEN1BLM | |
| Hydrochloric Acid SCHEMBL6850585 | 1.00 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MAPTMEN1BLM | |
| Hydrochloric Acid SCHEMBL4538254 | 0.99 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2MAPTMEN1BLM | |
| Hydrochloric Acid SCHEMBL15545820 | 0.99 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2MAPTMEN1BLM | |
| Hydrochloric Acid SCHEMBL4950608 | 0.99 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2MAPTMEN1BLM | |
| SCHEMBL29466902 | 0.99 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2MAPTMEN1BLM | |
| SCHEMBL1059266 | 0.99 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2MAPTMEN1BLM | |
| Hoechst 33258 SCHEMBL6942659 | 0.94 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPTMEN1BLM | |
| SCHEMBL15969230 | 0.94 | ALDH1A1 (0.90) | ALDH1A1SMN1; SMN2MAPTMEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3763 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3841097-B1 | 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER | BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) | 2026-05-20 | — | — | EP | claimed |
| WO-2026102332-A1 | NERVE AND TUMOR HOMING AGENTS AND METHODS OF USE THEREOF | Blaze Bioscience, Inc. (US) | 2026-05-15 | — | — | WO | claimed |
| US-20250128238-A1 | SEPARATION MEDIA CONTAINING DYES | DONALDSON COMPANY, INC. | 2025-04-24 | — | — | US | claimed |
| US-20250084452-A1 | BIOLOGICAL INDICATOR FOR DETERMINING THE EFFICACY OF A STERILIZATION PROCESS AND METHODS OF USE | TERRAGENE LLC | 2025-03-13 | — | — | US | claimed |
| EP-4514994-A1 | NUCLEIC ACID EXTRACTION AND ISOLATION WITH HEAT LABILE SILANES AND CHEMICALLY MODIFIED SOLID SUPPORTS | Cepheid (US) | 2025-03-05 | — | — | EP | claimed |
| EP-3610259-B1 | HIGH-BRIGHTNESS FLUOROPHORES | UNIV MICHIGAN TECH (US) | 2025-02-12 | — | — | EP | claimed |
| CN-119365521-A | Three-dimensional cell culture system and method | 知名医药公司 | 2025-01-24 | — | — | CN | claimed |
| WO-2024156920-A1 | FLUOROGENIC POLYMETHINE DYES | Universität Zürich (CH) | 2024-08-02 | — | — | WO | claimed |
| EP-4354139-A1 | NON-INVASIVE METHOD OF CELL IMAGING | Fundación Carlos Simón para la Investigación en Salud de la Mujer (ES) | 2024-04-17 | — | — | EP | claimed |
| US-20240035016-A1 | NUCLEIC ACID EXTRACTION AND ISOLATION WITH HEAT LABILE SILANES AND CHEMICALLY MODIFIED SOLID SUPPORTS | CEPHEID | 2024-02-01 | — | — | US | claimed |
| EP-0882801-A1 | Method for selecting cDNA fragments | INSTITUT PASTEUR DE LILLE (FR) | 1998-12-09 | — | — | EP | claimed |
| WO-1998050536-A1 | HMGI PROTEINS IN TUMORS AND OBESITY | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 1998-11-12 | — | — | WO | claimed |
| EP-0838527-A1 | Method for measuring the concentration of polynucleotides | Kyoto Daiichi Kagaku Co., Ltd. (JP) | 1998-04-29 | — | — | EP | claimed |
| EP-0838528-A1 | Method for measuring the concentration of polynucleotides | Kyoto Daiichi Kagaku Co., Ltd. (JP) | 1998-04-29 | — | — | EP | claimed |
| EP-0471758-B1 | METHOD TO PRESELECT THE SEX OF OFFSPRING | US AGRICULTURE (US) | 1996-09-11 | — | — | EP | claimed |
| EP-0478630-B1 | METHOD FOR DETECTING SPECIFIC NUCLEIC ACID SEQUENCES AND APPLICATIONS OF SAME | CIS BIO INTERNATIONAL (FR) | 1993-09-01 | — | — | EP | claimed |
| EP-0516381-A2 | Species-specific method for identifying infecticity of eimeria species | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | claimed |
| EP-0471758-A4 | METHOD TO PRESELECT THE SEX OF OFFSPRING | US AGRICULTURE (US) | 1992-05-06 | — | — | EP | claimed |
| EP-0471758-A1 | METHOD TO PRESELECT THE SEX OF OFFSPRING. | US AGRICULTURE (US) | 1992-02-26 | — | — | EP | claimed |
| WO-1990013303-A1 | METHOD TO PRESELECT THE SEX OF OFFSPRING | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1990-11-15 | — | — | WO | claimed |