Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627557 | 0.96 | — | — | |
| Iodide SCHEMBL28928432 | 0.92 | — | — | |
| Bromide SCHEMBL28672896 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL1115730 | 0.79 | — | — | |
| Sulfuric Acid SCHEMBL11648716 | 0.78 | CA5A (0.33) | — | |
| Hydrochloric Acid SCHEMBL2582962 | 0.76 | — | — | |
| SCHEMBL353008 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL31338827 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7118282 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL6871705 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105985-B | Method for constructing Lu Meipai long intermediate by asymmetric hydrogenation and lumepiquat chloride intermediate | 南方科技大学坪山生物医药研究院 | 2024-04-16 | — | — | CN | claimed |
| CN-113563255-B | Preparation method of remifloxacin intermediate | 成都倍特药业股份有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-113024554-B | Preparation method of rumepilone intermediate | 上海法默生物科技有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-110563591-B | Environment-friendly synthesis method of N, N, N' -trimethylethylenediamine | 西安瑞联新材料股份有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-105713086-B | Panyi and dimethylation antibody and preparation method thereof | 复旦大学 | 2022-04-12 | — | — | CN | claimed |
| CN-114105985-A | Method for constructing rumepilone intermediate through asymmetric hydrogenation and rumepilone intermediate | 南方科技大学坪山生物医药研究院 | 2022-03-01 | — | — | CN | claimed |
| CN-113563255-A | Preparation method of Rifloxacin intermediate | 成都倍特药业股份有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-113024554-A | Preparation method of rumepilone intermediate | 上海法默生物科技有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-110563591-A | Environment-friendly synthesis method of N, N, N' -trimethylethylenediamine | 西安瑞联新材料股份有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-105349593-A | Pethidine hydrochloride preparation method | ZHEJIANG ESIGMA BIOTECHNOLOGY CO LTD | 2016-02-24 | — | — | CN | claimed |
| CN-104402842-A | Synthetic method of piperazidines drug intermediate | SUZHOU JONATHAN NEW MATERIALS TECHNOLOGY CO LTD | 2015-03-11 | — | — | CN | claimed |
| CN-103408432-A | Synthetic process of 2-dimethylaminoethyl chloride hydrochloride | KUNSHAN SANYOU PHARMACEUTICAL MATERIAL CO LTD | 2013-11-27 | — | — | CN | claimed |
| CN-120518506-A | Rivastigmine derivative modified based on electron donating effect, and preparation method and application thereof | 沈阳药科大学 | 2025-08-22 | — | — | CN | disclosed |
| CN-116514739-B | 1, 4-Dimethylpiperazine and preparation method thereof | 天津绿菱气体股份有限公司 | 2025-07-22 | — | — | CN | disclosed |
| WO-2025106780-A1 | RXFP1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2025-05-22 | — | — | WO | disclosed |
| EP-3917527-B1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC (US) | 2025-04-23 | — | — | EP | disclosed |
| US-4015003-A | Antidepressant 1,1a,6,10b-tetrahydrodibenzo[a,e]-cyclopropa-[c]-cyclohepten-6-substituted oximes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-4014936-A | Antidepressant 1,1a,6,10b-tetrahydrodibenzo[a,e]-cyclopropa-[c]-cyclohepten-6-substituted oximes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-4008331-A | Antidepressant 1,1a,6,10b-tetrahydrodibenzo-[a,e]-cyclopropa-[c]-cyclohepten-6-substituted oximes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3960956-A | Antidepressant 1,1a,6,10b-tetrahydrodibenzo(a,e)-cyclo-propa(c) cyclohepten-6-substituted oximes | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1976-06-01 | — | — | US | disclosed |