Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 4/20 | 0.52 |
| ▸ | GABRB2 known ✓ | P47870 | 4/20 | 0.52 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.42 |
| ▸ | KCNH2 known ✓ | Q12809 | 2/20 | 0.39 |
| ▸ | SCN5A known ✓ | Q14524 | 2/20 | 0.39 |
| ▸ | CACNA1C known ✓ | Q13936 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27320869 | 0.97 | GABRA1 (0.55) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| Ammonia Solution, Strong SCHEMBL27691931 | 0.94 | GABRA1 (0.52) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| SCHEMBL245773 | 0.94 | GABRA1 (0.57) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| Bromomethane SCHEMBL27482045 | 0.92 | GABRA1 (0.56) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| Iodomethane SCHEMBL27515300 | 0.92 | GABRA1 (0.50) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| Methane SCHEMBL28776675 | 0.92 | GABRA1 (0.55) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| SCHEMBL31498538 | 0.92 | GABRA1 (0.55) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| Methylamine SCHEMBL27545014 | 0.92 | GABRA1 (0.55) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| Ethylamine SCHEMBL27517993 | 0.90 | GABRA1 (0.48) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| SCHEMBL9000240 | 0.89 | GABRA1 (0.52) | GABRA1GABRB2TAAR1HTR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292703-B | Phosphorus-free full-bio-based flame-retardant epoxy resin with excellent thermal and mechanical properties and green preparation method thereof | 南京工业大学 | 2022-06-03 | — | — | CN | claimed |
| CN-113292703-A | Phosphorus-free full-bio-based flame-retardant epoxy resin with excellent thermal and mechanical properties and green preparation method thereof | 南京工业大学 | 2021-08-24 | — | — | CN | claimed |
| CN-107418287-B | Method for producing coating curing agent and application of coating curing agent in coating | 上海药合生化科技有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-109134229-B | Method for preparing cypress oleyl alcohol | 中国农业科学院农业环境与可持续发展研究所 | 2020-09-04 | — | — | CN | claimed |
| CN-108166158-B | Preparation method of waterproof antibacterial double-layer electret electrospun nanofiber composite window screen material | 浙江西大门新材料股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-109134229-A | A method of preparing cypress oleyl alcohol | 中国农业科学院农业环境与可持续发展研究所 | 2019-01-04 | — | — | CN | claimed |
| CN-108166158-A | The preparation method of water-proof antibiotic bilayer electret electro spinning nano fiber complex-aperture yarn material | 符思敏 | 2018-06-15 | — | — | CN | claimed |
| CN-103755658-B | Benzolactam compounds and synthetic method thereof and application | MAX (RUDONG) CHEMICALS CO., LTD. (CN) | 2016-06-01 | — | — | CN | claimed |
| CN-103333503-B | Blend rubber and preparation method thereof | CHINA SHENHUA ENERGY CO LTD | 2015-07-15 | — | — | CN | claimed |
| CN-102633708-B | Synthesizing and purifying method of midbody 9-(2-ethoxy) carbazole | WUHAN UNIVERSITY OF TECHNOLOGY (CN) | 2014-10-01 | — | — | CN | claimed |
| CN-103755658-A | Benzene and lactam compound and synthetic method and application thereof | MAX RUDONG CHEMICALS CO LTD | 2014-04-30 | — | — | CN | claimed |
| CN-103611197-A | Method for preparing nano-fiber-based guided bone regeneration membrane | WUXI ZHONGKE GUANGYUAN BIOMATERIALS CO LTD | 2014-03-05 | — | — | CN | claimed |
| CN-101952237-B | Bromide-free TEMPO-mediated oxidation of the primary alcohol in carbohydrate under two-phase conditions | CHONGQING HUAPONT PHARM CO LTD | 2014-01-08 | — | — | CN | claimed |
| CN-103333503-A | Blend rubber and preparation method thereof | CHINA SHENHUA ENERGY CO LTD | 2013-10-02 | — | — | CN | claimed |
| CN-102633708-A | Synthesizing and purifying method of midbody 9-(2-ethoxy) carbazole | UNIV WUHAN TECH | 2012-08-15 | — | — | CN | claimed |
| CN-101952237-A | Bromide-free TEMPO-mediated oxidation of the primary alcohol in carbohydrate under two-phase conditions | CHONGQING SHENGKAI SCIENCE & T | 2011-01-19 | — | — | CN | claimed |
| CN-100360543-C | Method for preparing ammonium salts of cyclohexanpentol phosphate ester | UNIV SICHUAN NORMAL (CN) | 2008-01-09 | — | — | CN | claimed |
| CN-1830986-A | Method for preparing ammonium salts of cyclohexanpentol phosphate ester | UNIV SICHUAN NORMAL (CN) | 2006-09-13 | — | — | CN | claimed |
| CN-115304745-B | Resveratrol and isovanillin based bio-based composite epoxy resin and preparation method thereof | 南京工业大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-1042149-A | Tetrahydropyrimidines, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-05-16 | — | — | CN | disclosed |