Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4059263

Cc1c(C)c(N)c(C)c(C)c1N.Cl

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PIK3CA known ✓ P42336 1/20 0.33
GAA known ✓ P10253 1/20 0.32
POLB P06746 2/20 0.35
CYP3A4 P08684 3/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2142090 1.00 POLB (0.35) POLBCYP3A4TSHRALDH1A1TDP1
SCHEMBL263364 0.95 POLB (0.37) POLBCYP3A4TSHRALDH1A1TDP1
Hydrochloric Acid SCHEMBL6865152 0.90 POLB (0.35) POLBCYP3A4TSHRALDH1A1TDP1
SCHEMBL392463 0.90 POLB (0.35) POLBCYP3A4TSHRALDH1A1TDP1
SCHEMBL25011939 0.86 POLB (0.33) POLBCYP3A4TSHRALDH1A1TDP1
Hydrochloric Acid SCHEMBL8982051 0.86 POLB (0.33) POLBCYP3A4TSHRALDH1A1TDP1
Silver SCHEMBL7074850 0.86 POLB (0.33) POLBCYP3A4TSHRALDH1A1TDP1
Hydrochloric Acid SCHEMBL29126802 0.86 POLB (0.33) POLBCYP3A4TSHRALDH1A1TDP1
SCHEMBL682204 0.86 POLB (0.33) POLBCYP3A4TSHRALDH1A1TDP1
SCHEMBL6568058 0.84 POLB (0.37) POLBCYP3A4TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114292896-B Helicobacter pylori drug sensitivity detection method 四川大学华西医院 2023-08-22 CN claimed
CN-112853409-B Silver-containing plating solution and preparation method of foam metal material 哈尔滨工业大学(深圳) 2022-07-22 CN claimed
CN-114292896-A Helicobacter pylori drug sensitivity detection method 四川大学华西医院 2022-04-08 CN claimed
CN-110255909-B Enamel coating for pot body and preparation method thereof 宁波市金象厨具有限公司 2022-04-01 CN claimed
CN-112853409-A Silver-containing plating solution and preparation method of foam metal material 哈尔滨工业大学(深圳) 2021-05-28 CN claimed
CN-110628592-A Device for rapidly detecting minimum inhibitory concentration of gonococcus, preparation method and detection method 浙江大学 2019-12-31 CN claimed
WO-2019053137-A1 METHOD FOR SCREENING COMPOUNDS THAT MODULATE THE ACTIVITY OF THE ELECTRON TRANSPORT CHAIN IMG PHARMA BIOTECH, S.L. (ES) 2019-03-21 WO claimed
CN-104792986-B A kind of vaginitiss many index combined detection kit 江苏宜偌维盛生物技术有限公司 2017-03-08 CN claimed
CN-104792986-A Multi-indexes joint detection kit for vaginitis JIANGSU INV BIO TECHNOLOGY CO LTD 2015-07-22 CN claimed
CN-100554949-C Oxidase test test fluid and testing tube thereof LI BAI (CN) 2009-10-28 CN claimed
CN-101029873-A Liquid for testing oxidase and its testing tube BAI LI (CN) 2007-09-05 CN claimed
US-4355113-A Over the counter swab kit for self detection of gonorrhea in the male using saline ampule MENNEN FREDERICK C 1982-10-19 US claimed
US-4340670-A Method of using over the counter swab kit for self detection of gonorrhea in the male using tetramethyl chromogen ampul MENNEN FREDERICK C 1982-07-20 US claimed
US-4018653-A Instrument for the detection of Neisseria gonorrhoeae without culture U.S. PACKAGING CORPORATION (US) 1977-04-19 US claimed
EP-4735578-A1 PARARHIZOBIUM STRAINS, COMPOSITIONS AND USES THEREOF AS PLANT GROWTH STIMULANTS Universitat de Barcelona (ES) 2026-05-06 EP disclosed
CN-120005757-A Penaeus vannamei source bdellovibrio and application thereof 宁波市海洋与渔业研究院 2025-05-16 CN disclosed
EP-4484547-A1 PARARHIZOBIUM STRAINS, COMPOSITIONS AND USES THEREOF AS PLANT GROWTH STIMULANTS Universitat de Barcelona (ES) 2025-01-01 EP disclosed
EP-0243100-A2 Method for processing light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1987-10-28 EP disclosed
US-4355113-A Over the counter swab kit for self detection of gonorrhea in the male using saline ampule MENNEN FREDERICK C 1982-10-19 US disclosed
US-3954564-A Instrument for the detection of neisseria gonorrhoeae and the like MENNEN FREDERICK C 1976-05-04 US disclosed