Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.47 |
| ▸ | FDPS | P14324 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL337316 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL1428606 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL17784169 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL2788700 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL5705085 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL2788661 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL3652706 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL5705126 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL7742696 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL6329495 | 1.00 | SMPD1 (0.47) | SMPD1FDPSDNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899205-A | Preparation method and application of single-site metal catalyst auxiliary agent | 中国石油化工股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| WO-2025049276-A1 | METHODS AND SYSTEMS FOR PROCESSING AND RECYCLING OF CARBONACEOUS MATERIALS | NANOTECH ENERGY, INC. (US) | 2025-03-06 | — | — | WO | claimed |
| CN-116135920-A | Additive for accelerating anaerobic biodegradation of high polymer material and preparation and use methods thereof | 纳米及先进材料研发院有限公司 | 2023-05-19 | — | — | CN | claimed |
| CN-112876902-B | Flame-retardant thermal expansion microcapsule and preparation method and application thereof | 唐山开滦化工科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-114989349-A | High-temperature-resistant thickening agent for calcium chloride weighted fracturing fluid and preparation method and application thereof | 中国石油天然气股份有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114790385-A | Calcium chloride-weighted high-density slickwater as well as preparation method and application thereof | 中国石油天然气股份有限公司 | 2022-07-26 | — | — | CN | claimed |
| CN-113563507-A | Anionic acrylamide polymer, calcium chloride weighted fracturing fluid containing anionic acrylamide polymer and preparation methods of anionic acrylamide polymer and calcium chloride weighted fracturing fluid | 中国石油天然气股份有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-112876902-A | Flame-retardant thermal expansion microcapsule and preparation method and application thereof | 唐山开滦化工科技有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-106995419-B | Fluorescent probe with aggregation-induced emission property and preparation method and application thereof | 华南理工大学 | 2020-02-11 | — | — | CN | claimed |
| CN-110591394-A | Modified emulsified asphalt for micro surfacing | 江苏增光复合材料科技有限公司 | 2019-12-20 | — | — | CN | claimed |
| WO-2006095234-A2 | INTEGRIN TARGETED SYNTHETIC LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO IMAGING S.P.A. (IT) | 2006-09-14 | — | — | WO | claimed |
| EP-0983060-A4 | SOLID POROUS MATRICES AND METHODS OF MAKING AND USING THE SAME | IMARX PHARMACEUTICAL CORP (US) | 2002-04-24 | — | — | EP | claimed |
| US-20020039594-A1 | SOLID POROUS MATRICES AND METHODS OF MAKING AND USING THE SAME | IMARX THERAPEUTICS, INC. | 2002-04-04 | — | — | US | claimed |
| EP-0983060-A1 | SOLID POROUS MATRICES AND METHODS OF MAKING AND USING THE SAME | IMARX PHARMACEUTICAL CORP. (US) | 2000-03-08 | — | — | EP | claimed |
| EP-0598663-B1 | A pretreatment method for blood analysis | SYSMEX CORP (JP) | 2000-02-02 | — | — | EP | claimed |
| WO-1998051282-A1 | SOLID POROUS MATRICES AND METHODS OF MAKING AND USING THE SAME | IMARX PHARMACEUTICAL CORP. (US) | 1998-11-19 | — | — | WO | claimed |
| US-5480757-A | AMINES AND AMMONIUM COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1996-01-02 | — | — | US | claimed |
| EP-0686884-A1 | Two component electrophotographic developers and preparation method | EASTMAN KODAK COMPANY (US) | 1995-12-13 | — | — | EP | claimed |
| EP-0598663-A2 | A pretreatment method for blood analysis | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1994-05-25 | — | — | EP | claimed |
| EP-0338591-A2 | Nucleic acid extraction method | MICROPROBE CORPORATION (US) | 1989-10-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020039594-A1 | SOLID POROUS MATRICES AND METHODS OF MAKING AND USING THE SAME | EXOSC9, EXOSC5, EXOSC4 | SMPD1 60/4885FDPS 2909/4885DNM1 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.