Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL28863388 | 1.00 | TSHR (0.44) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Butane SCHEMBL465278 | 1.00 | — | — | |
| Butane SCHEMBL27927071 | 1.00 | TSHR (0.44) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Butane SCHEMBL5851369 | 1.00 | — | — | |
| Butane SCHEMBL18039280 | 1.00 | — | — | |
| Butane SCHEMBL814744 | 1.00 | — | — | |
| Butane SCHEMBL12504128 | 0.93 | — | — | |
| Butane SCHEMBL3109038 | 0.93 | — | — | |
| Butane SCHEMBL10400622 | 0.93 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Butane SCHEMBL2860854 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111019269-B | PVC cable material and preparation method thereof | 江苏达胜高聚物股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-111019269-A | PVC cable material and preparation method thereof | 江苏达胜高聚物股份有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-109824716-A | A kind of recoverying and utilizing method of tributyltin chloride | 南通濠泰化工产品有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-109824717-A | A method of by low pure tributyltin chloride preparation monobutyl-tin-trichloride and dibutyl tin dichloride | 南通濠泰化工产品有限公司 | 2019-05-31 | — | — | CN | claimed |
| US-4519431-A | COUPLED WITH A TIN HALIDE COMPOUND FOR USE IN RADIAL TIRES | BRIDGESTONE TIRE COMPANY LIMITED (JP) | 1985-05-28 | — | — | US | claimed |
| WO-2024225003-A1 | COMPOSITION FOR PEST CONTROL AND PHOTOSTABILITY METHOD FOR PEST CONTROL COMPONENT | 大日本除蟲菊株式会社 | 2024-10-31 | — | — | WO | disclosed |
| EP-3802113-B1 | TYRE FOR VEHICLE WHEELS | PIRELLI (IT) | 2024-02-07 | — | — | EP | disclosed |
| CN-116744793-A | Acarid-repellent composition and acarid-repellent product | 大日本除虫菊株式会社 | 2023-09-12 | — | — | CN | disclosed |
| US-11631897-B2 | Ionic liquid additive for lithium-ion battery | HIGH TECH BATTERY INC. (TW) | 2023-04-18 | — | — | US | disclosed |
| US-20230115837-A1 | INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS | Sanford Burnham Prebys Medical Discovery Institute | 2023-04-13 | — | — | US | disclosed |
| US-11626620-B2 | Ionic liquid additive for lithium-ion battery | HIGH TECH BATTERY INC. (TW) | 2023-04-11 | — | — | US | disclosed |
| WO-2023037840-A1 | FIXED-AMOUNT SPRAY AEROSOL PRODUCT FOR CONTROLLING HARMFUL MICROORGANISMS AND METHOD FOR CONTROLLING HARMFUL MICROORGANISMS USING SAME | 大日本除蟲菊株式会社 | 2023-03-16 | — | — | WO | disclosed |
| US-20050217757-A1 | Preflux, flux, solder paste and method of manufacturing lead-free soldered body | ESE INDUSTRIES (S) PTE LTD (SG) | 2005-10-06 | — | — | US | disclosed |
| EP-0549808-A1 | TRANSPARENT PLASTIC MATERIAL | SEIKO EPSON CORPORATION (JP) | 1993-07-07 | — | — | EP | disclosed |
| US-5027157-A | Developing device provided with electrodes for inducing a traveling wave on the developing material | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| US-4867541-A | FILM FORMED BY PLASMA POLYMERIZATION OF PHTHALOCYANINE COMPOUND | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1989-09-19 | — | — | US | disclosed |
| US-4828369-A | ELECTROLYTES, PLASMA POLYMERIZATION OF HYDROCARBON, ALKALI METAL /COMPOUND/, ELECTRONEGATIVITY | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1989-05-09 | — | — | US | disclosed |
| US-4519431-A | COUPLED WITH A TIN HALIDE COMPOUND FOR USE IN RADIAL TIRES | BRIDGESTONE TIRE COMPANY LIMITED (JP) | 1985-05-28 | — | — | US | disclosed |
| US-4292252-A | Process for preparing organotin esters | TENNECO CHEMICALS INC. (US) | 1981-09-29 | — | — | US | disclosed |
| US-4231949-A | Process for preparing organotin esters | ALBRIGHT & WILSON LIMITED (GB) | 1980-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115837-A1 | INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS | API5, XIAP, BIRC5 | TSHR 4554/4885LMNA 508/4885THRB 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.