Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.54 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.95 |
| ▸ | DHPS | P49366 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8818186 | 1.00 | MEN1 (0.95) | MEN1KMT2ADHPSPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL5319582 | 1.00 | MEN1 (0.95) | MEN1KMT2ADHPSPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL4168696 | 1.00 | MEN1 (0.95) | MEN1KMT2ADHPSPRSS1PRSS2 | |
| Dodine SCHEMBL560209 | 1.00 | MEN1 (0.95) | MEN1KMT2ADHPSPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL899169 | 1.00 | MEN1 (0.95) | MEN1KMT2ADHPSPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL1123530 | 1.00 | MEN1 (0.95) | MEN1KMT2ADHPSPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL27504627 | 1.00 | MEN1 (0.95) | MEN1KMT2ADHPSPRSS1PRSS2 | |
| SCHEMBL1138747 | 0.97 | MEN1 (1.00) | MEN1KMT2ADHPSPRSS1PRSS2 | |
| SCHEMBL5300899 | 0.97 | MEN1 (1.00) | MEN1KMT2ADHPSPRSS1PRSS2 | |
| SCHEMBL4104867 | 0.97 | MEN1 (1.00) | MEN1KMT2ADHPSPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717546-A | Method for preparing organic pigment yellow and pigment orange by modifying attapulgite | 宇虹颜料股份有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-108752974-A | A kind of preparation method of diphenyl amine organic pigment | 山东宇虹新颜料股份有限公司 | 2018-11-06 | — | — | CN | claimed |
| JP-5194150-A | — | — | None | — | — | JP | disclosed |
| CN-113717546-A | Method for preparing organic pigment yellow and pigment orange by modifying attapulgite | 宇虹颜料股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-108752974-B | A kind of preparation method of diphenyl amine organic pigment | 山东宇虹新颜料股份有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-108752974-A | A kind of preparation method of diphenyl amine organic pigment | 山东宇虹新颜料股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| EP-3042718-A1 | DEVICE FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION | Dietz, Ulrich (DE) | 2016-07-13 | — | — | EP | disclosed |
| US-20160122686-A1 | DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION | DIETZ ULRICH (DE) | 2016-05-05 | — | — | US | disclosed |
| EP-2585420-B1 | METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION | DIETZ ULRICH (DE) | 2016-04-06 | — | — | EP | disclosed |
| US-9127233-B2 | Device and method for solubilizing, separating, removing and reacting carboxylic acids in oils, fats, aqueous or organic solutions by means of micro-or nanoemulsification | Dietz, Ulrich (DE) | 2015-09-08 | — | — | US | disclosed |
| CN-103539706-A | Alkyl guanidine salt and preparation method thereof | YANG XIN RONG | 2014-01-29 | — | — | CN | disclosed |
| EP-2585420-A2 | DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION | Dietz, Ulrich (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-20130090488-A1 | DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION | DIETZ ULRICH (DE) | 2013-04-11 | — | — | US | disclosed |
| WO-2011160857-A2 | DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION | DIETZ ULRICH (DE) | 2011-12-29 | — | — | WO | disclosed |
| EP-2399885-A1 | Device and method for solubilizing, separating, removing and reacting carboxylic acids in aqueous or organic solutions by means of micro- or nanoemulsification | Dietz, Ulrich (DE) | 2011-12-28 | — | — | EP | disclosed |
| WO-2009138806-A1 | NOVEL LIPOSOME COCKTAIL FORMULATIONS CONTAINING DOXORUBICIN AND THE POTENT MULTIDRUG RESISTANCE INHIBITOR AMIODARONE | DENDRIGEN S.A. (GR) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009138806-A1 | NOVEL LIPOSOME COCKTAIL FORMULATIONS CONTAINING DOXORUBICIN AND THE POTENT MULTIDRUG RESISTANCE INHIBITOR AMIODARONE | DENDRIGEN S.A. (GR) | 2009-11-19 | — | — | WO | disclosed |
| WO-2001079359-A2 | GUANIDINIUM AND ISOTHIOURONIUM COMPOUNDS AND METHODS FOR THEIR USE | UNIVERSITY OF VICTORIA INNOVATION AND DEVELOPMENT CORPORATION (CA) | 2001-10-25 | — | — | WO | disclosed |
| JP-H05194150-A | HAIR COSMETIC | LION CORP | 1993-08-03 | — | — | JP | disclosed |