Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.47 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | DUSP5 | Q16690 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31709159 | 1.00 | PTGES (0.49) | PTGESDUSP5PTPN1PTGS1APP | |
| Potassium Ion SCHEMBL31235662 | 0.97 | PTGES (0.49) | PTGESDUSP5PTPN1PTGS1APP | |
| Potassium Ion SCHEMBL5036933 | 0.97 | PTGES (0.49) | PTGESDUSP5PTPN1PTGS1APP | |
| SCHEMBL5292700 | 0.86 | DUSP5 (0.46) | DUSP5PTPN1APPTHRBSIRT1 | |
| SCHEMBL1070219 | 0.85 | PTPN1 (0.58) | PTGESDUSP5PTPN1PTGS1APP | |
| SCHEMBL8008835 | 0.80 | NT5E (0.47) | DUSP5PTPN1APPTHRBSIRT1 | |
| SCHEMBL31099415 | 0.80 | NT5E (0.47) | DUSP5PTPN1APPTHRBSIRT1 | |
| SCHEMBL29627069 | 0.80 | NT5E (0.47) | DUSP5PTPN1APPTHRBSIRT1 | |
| Sulfuric Acid SCHEMBL8333659 | 0.79 | PTGES (0.51) | PTGESPTPN1PRMT1PTPN7PTPN11 | |
| SCHEMBL29691763 | 0.79 | PTPN1 (0.55) | DUSP5PTPN1PTGS1APPTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11752086-B2 | Topical formulations and methods | MYOCEPT INC. (US) | 2023-09-12 | — | — | US | disclosed |
| CN-111182884-B | Inorganic sunscreen coated with adducts of hydroxycinnamic esters and silanols | 维佐尔有限责任公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115594987-A | Acid orange disazo dye and preparation method thereof | 金华恒利康化工有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-112341836-B | Weak acid red bisazo dye and preparation method thereof | 金华恒利康化工有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-112341836-A | Weak acid red bisazo dye and preparation method thereof | 金华恒利康化工有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-110612093-A | Topical formulations and methods | 麦欧赛普特股份有限公司 | 2019-12-24 | — | — | CN | disclosed |
| WO-2018148338-A1 | TOPICAL FORMULATIONS AND METHODS | PETERS LARS ERIK (US) | 2018-08-16 | — | — | WO | disclosed |
| US-20170105967-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF INFLAMMATORY SKIN CONDITIONS USING ALLANTOIN | SCIODERM, INC. (US) | 2017-04-20 | — | — | US | disclosed |
| US-20170105968-A1 | Compositions and Methods for Treatment of Inflammatory Skin Conditions Using Allantoin | SCIODERM, INC. (US) | 2017-04-20 | — | — | US | disclosed |
| US-20170049749-A1 | METHODS FOR TREATING BURNS USING ALLANTOIN | Scioderm.Inc. (US) | 2017-02-23 | — | — | US | disclosed |
| US-20060045926-A1 | Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin | NIMNI MARCEL | 2006-03-02 | — | — | US | disclosed |
| US-20030157137-A1 | Emulsified skin care composition containing salicylic acid, lanolin oil, and propylene glycol | ALWYN COMPANY, INC. | 2003-08-21 | — | — | US | disclosed |
| US-20030147968-A1 | Allantoin-containing preparations for administration as gels and aerosols | ALWYN COMPANY, INC. | 2003-08-07 | — | — | US | disclosed |
| WO-2003053369-A1 | ALLANTOIN-CONTAINING PREPARATIONS FOR ADMINISTRATION AS GELS AND AEROSOLS | ALWYN COMPANY, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
| WO-2003041688-A1 | METHODS FOR TREATMENT OF INFLAMMATORY DISEASES | ALWYN COMPANY, INC. (US) | 2003-05-22 | — | — | WO | disclosed |
| WO-2003041651-A2 | ALLATOIN-CONTAINING SKIN CREAM | ALWYN COMPANY, INC. (US) | 2003-05-22 | — | — | WO | disclosed |
| US-20020054895-A1 | And at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water; skin protectants | ALWYN COMPANY, INC. | 2002-05-09 | — | — | US | disclosed |
| US-20020055531-A1 | Methods for treatment of inflammatory diseases | SWEEN, MAURICE ALWYN | 2002-05-09 | — | — | US | disclosed |
| US-6376557-B1 | TRANSDERMAL SUPPLYING | ZAVERI CHANDA BHUWALKA (US) | 2002-04-23 | — | — | US | disclosed |
| WO-2001068107-A1 | HAIR RESTORATION FORMULATION | ZAVERI CHANDA BHUWALKA (US) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049749-A1 | METHODS FOR TREATING BURNS USING ALLANTOIN | ALKBH1, ALKBH3, FAAH2 | PTGS1 133/4885THRB 4856/4885PTGES 148/4885 |
| US-20060045926-A1 | Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin | COL1A1, COL14A1, COL2A1 | PTGS1 149/4885THRB 1662/4885PTGES 177/4885 |
| US-20170105967-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF INFLAMMATORY SKIN CONDITIONS USING ALLANTOIN | CUTA, ITCH, ARG1 | PTGS1 192/4885THRB 4521/4885PTGES 180/4885 |
| US-20170105968-A1 | Compositions and Methods for Treatment of Inflammatory Skin Conditions Using Allantoin | CUTA, ITCH, ARG1 | PTGS1 208/4885THRB 4529/4885PTGES 191/4885 |
| US-11752086-B2 | Topical formulations and methods | KRT18, ANXA3, VIP | PTGS1 2127/4885THRB 3697/4885PTGES 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.