Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11437100 | 1.00 | — | — | |
| Methane SCHEMBL27978512 | 0.95 | — | — | |
| SCHEMBL28154792 | 0.94 | TSHR (0.40) | — | |
| SCHEMBL16435 | 0.94 | — | — | |
| Ethylene SCHEMBL27323973 | 0.91 | — | — | |
| SCHEMBL11822312 | 0.89 | — | — | |
| Methylene Chloride SCHEMBL5785447 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL6917054 | 0.89 | — | — | |
| Chloroform SCHEMBL4937516 | 0.89 | — | — | |
| Water SCHEMBL6706113 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987850-B1 | Reinforced tissue implants and methods of manufacture and use | ETHICON INC (US) | 2016-06-29 | — | — | EP | disclosed |
| US-8691259-B2 | Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration | DEPUY MITEK, LLC (US) | 2014-04-08 | — | — | US | disclosed |
| EP-1987850-A1 | Reinforced tissue implants and methods of manufacture and use | Ethicon, Incorporated (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1216717-B1 | Method of making a reinforced tissue implant | ETHICON INC (US) | 2008-07-09 | — | — | EP | disclosed |
| US-20060067967-A1 | Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration | DEPUY MITEK, INC. (US) | 2006-03-30 | — | — | US | disclosed |
| US-6884428-B2 | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration | DEPUY MITEK, INC. (US) | 2005-04-26 | — | — | US | disclosed |
| US-6852330-B2 | Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration | DEPUY MITEK, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1216718-B1 | Reinforced foam implants for soft tissue repair and regeneration | ETHICON INC (US) | 2004-10-06 | — | — | EP | disclosed |
| US-20030193104-A1 | Reinforced tissue implants and methods of manufacture and use | MELICAN MORA CAROLYNNE (US) | 2003-10-16 | — | — | US | disclosed |
| US-20030147935-A1 | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration | ETHICON, INC. (US) | 2003-08-07 | — | — | US | disclosed |
| US-6599323-B2 | Biocompatible tissue implant comprising bioabsorbable polymeric foam having open cell pore structure and reinforcement formed of biocompatible mesh-containing material, in which pores of foam penetrate mesh and interlock | ETHICON, INC. | 2003-07-29 | — | — | US | disclosed |
| US-20020127265-A1 | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration | DEPUY MITEK, LLC | 2002-09-12 | — | — | US | disclosed |
| US-20020119177-A1 | Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration | DEPUY MITEK HOLDING CORPORATION | 2002-08-29 | — | — | US | disclosed |
| US-20020120348-A1 | Reinforced tissue implants and methods of manufacture and use | ETHICON, INC. | 2002-08-29 | — | — | US | disclosed |
| EP-1216718-A1 | Reinforced foam implants for soft tissue repair and regeneration | ETHICON, INC. (US) | 2002-06-26 | — | — | EP | disclosed |
| EP-1216717-A1 | Reinforced tissue implants and methods of manufacture and use | ETHICON, INC. (US) | 2002-06-26 | — | — | EP | disclosed |
| EP-0288876-B1 | Electrophotographic plate | HITACHI CHEMICAL CO LTD (JP) | 1994-07-20 | — | — | EP | disclosed |
| EP-0288876-A2 | Electrophotographic plate | Hitachi Chemical Co., Ltd. (JP) | 1988-11-02 | — | — | EP | disclosed |