Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.36 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.36 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15281958 | 1.00 | CALM1 (0.41) | CALM1TSHRALDH1A1LOXL2TRPA1 | |
| Hydrochloric Acid SCHEMBL28147023 | 1.00 | CALM1 (0.41) | CALM1TSHRALDH1A1LOXL2TRPA1 | |
| Hydrochloric Acid SCHEMBL27999670 | 0.97 | CALM1 (0.39) | CALM1TSHRALDH1A1LOXL2TRPA1 | |
| Hydrochloric Acid SCHEMBL28828300 | 0.97 | CALM1 (0.39) | CALM1TSHRALDH1A1LOXL2TRPA1 | |
| Hydrochloric Acid SCHEMBL28207048 | 0.97 | CALM1 (0.39) | CALM1TSHRALDH1A1LOXL2TRPA1 | |
| Hydrochloric Acid SCHEMBL27993384 | 0.97 | CALM1 (0.39) | CALM1TSHRALDH1A1LOXL2TRPA1 | |
| Hydrochloric Acid SCHEMBL27993655 | 0.97 | CALM1 (0.39) | CALM1TSHRALDH1A1LOXL2TRPA1 | |
| Hydrochloric Acid SCHEMBL27714197 | 0.97 | CALM1 (0.39) | CALM1TSHRALDH1A1LOXL2TRPA1 | |
| SCHEMBL122055 | 0.97 | CALM1 (0.43) | CALM1TSHRALDH1A1LOXL2TRPA1 | |
| Hydrochloric Acid SCHEMBL9312565 | 0.95 | MAOB (0.36) | CALM1TSHRALDH1A1LOXL2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120059469-A | High-low temperature-resistant wear-resistant tearing-resistant fluorosilicone rubber compound and preparation method thereof | 广东京汕密封件有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-119912741-A | High-temperature-resistant rubber emulsion and preparation method and application thereof | 河北昊泽化工有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119639154-A | Fluororubber composition | 安徽鼎连高分子材料科技有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119504697-A | Cyclohexadiene derivative and preparation method thereof | 博璞诺（上海）医药科技发展有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-115960332-B | Hexamethylene diisocyanate composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119371943-A | 2-Methyl-1, 3-propanediol-based antifreeze fluid and preparation method thereof | 沧州市天津工业大学研究院 | 2025-01-28 | — | — | CN | claimed |
| CN-118930945-A | Microcellular fluoroelastomer compositions and methods of making the same | 上海森桓新材料科技有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118834483-A | Low-temperature-resistant fluororubber sealing material and preparation method thereof | 安徽同丰橡塑工业有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-118772557-A | Method for preparing sealing ring from perfluoro ether elastomer rubber compound | 上海森桓新材料科技有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118667270-A | Aging-resistant fluororubber material with low compression set rate and preparation method and application thereof | 四川道弘新材料股份有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-114214647-A | Method for synthesizing vitamin A acetate through electrochemical catalysis | 万华化学集团股份有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-113546679-A | Ionic liquid-ruthenium-based catalyst for catalyzing hydrochlorination of acetylene and preparation method and application thereof | 石河子大学 | 2021-10-26 | — | — | CN | claimed |
| CN-109438903-A | A kind of fire-retardant SBS composite material | 俞虹 | 2019-03-08 | — | — | CN | claimed |
| CN-108467612-A | A kind of environment-friendly water-based paint | 甘庆文 | 2018-08-31 | — | — | CN | claimed |
| CN-108102259-A | A kind of fluorubber and preparation method thereof | 沈阳赛亚橡胶制品有限公司 | 2018-06-01 | — | — | CN | claimed |
| CN-107474692-A | A kind of coating on hollow copper tubing inwall and preparation method thereof | 巢湖鹏远金属焊管有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-106349706-A | Silicone rubber cable sheath material with high flame resistance | 安徽蓝德集团股份有限公司 | 2017-01-25 | — | — | CN | claimed |
| US-9522915-B2 | Method for preparing an important intermediate of linagliptin | 2Y-CHEM, LTD. (CN) | 2016-12-20 | — | — | US | claimed |
| CN-105733050-A | Heat-resistant, oil-resistant and anti-flaming modified nitrile butadiene rubber composite | 合肥市再德高分子材料有限公司 | 2016-07-06 | — | — | CN | claimed |
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | 2Y-CHEM, LTD. (CN) | 2015-10-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | DPP4, DPP9, DPP3 | MAOB 2912/4885MAOA 2726/4885HTR2A 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.