Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 known ✓ | O95136 | 5/20 | 0.32 |
| ▸ | S1PR4 known ✓ | O95977 | 5/20 | 0.32 |
| ▸ | S1PR1 known ✓ | P21453 | 5/20 | 0.32 |
| ▸ | S1PR3 known ✓ | Q99500 | 5/20 | 0.32 |
| ▸ | S1PR5 known ✓ | Q9H228 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1231795 | 0.81 | EPHX1 (0.36) | EPHX1GBA1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL9743322 | 0.81 | EPHX1 (0.36) | EPHX1GBA1ALDH1A1TSHR | |
| SCHEMBL108964 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL16161992 | 0.79 | EPHX1 (0.54) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL29249261 | 0.79 | EPHX1 (0.37) | EPHX1GBA1ALDH1A1TSHR | |
| SCHEMBL14697350 | 0.79 | EPHX1 (0.37) | EPHX1GBA1ALDH1A1TSHR | |
| SCHEMBL9551513 | 0.79 | EPHX1 (0.37) | EPHX1GBA1ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL1779682 | 0.77 | EPHX1 (0.36) | EPHX1ALDH1A1TSHR | |
| SCHEMBL6660600 | 0.77 | ALDH1A1 (0.36) | EPHX1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL23420705 | 0.73 | EPHX1 (0.94) | EPHX1S1PR2S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7845351-B2 | Germicidal face mask | KIMBERLY-CLARK WORLDWIDE INC. (US) | 2010-12-07 | — | — | US | claimed |
| EP-1919996-B1 | ANTIMICROBIAL COMPOSITION | KIMBERLY CLARK CO (US) | 2009-08-26 | — | — | EP | claimed |
| US-20090014009-A1 | Toroidal endotracheal cuffs for ventilator associated pneumonia reduction | KIMBERLY-CLARK WORLDWIDE, INC. | 2009-01-15 | — | — | US | claimed |
| US-20070044801-A1 | Germicidal face mask | O&M HALYARD, INC. | 2007-03-01 | — | — | US | claimed |
| US-11203554-B2 | Anticaking agent for hygroscopic fertilizer | IMERYS USA, INC. (US) | 2021-12-21 | — | — | US | disclosed |
| EP-2411329-B1 | NATURAL AMORPHOUS SILICA FILLER PRODUCTS | IMERYS FILTRATION MINERALS INC (US) | 2021-05-19 | — | — | EP | disclosed |
| US-20200181037-A1 | ANTICAKING AGENT FOR HYGROSCOPIC FERTILIZER | IMERYS USA, INC. | 2020-06-11 | — | — | US | disclosed |
| EP-2207416-B1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | IMERYS FILTRATION MINERALS INC (US) | 2018-11-07 | — | — | EP | disclosed |
| US-9834684-B2 | Natural amorphous silica filler products | IMERYS FILTRATION MINERALS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| EP-2094184-B1 | YANKAUER SUCTION DEVICE | KIMBERLY CLARK CO (US) | 2012-07-04 | — | — | EP | disclosed |
| US-20120048145-A1 | NATURAL AMORPHOUS SILICA FILLER PRODUCTS | WORLD MINERALS, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| EP-2411329-A1 | NATURAL AMORPHOUS SILICA FILLER PRODUCTS | World Minerals, Inc. (US) | 2012-02-01 | — | — | EP | disclosed |
| US-6504582-B1 | Scratch resistant display and method of making same using homeotrophic liquid crystal silanes | 3M INNOVATIVE PROPERTIES CO | 2003-01-07 | — | — | US | disclosed |
| US-6504583-B2 | Scratch resistant computer touch panel; activating the siloxane material; applying a homeotropic organosilane compound to the siloxane layer so that a chemical bond is formed | 3M INNOVATIVE PROPERTIES COMPANY | 2003-01-07 | — | — | US | disclosed |
| EP-1155352-A4 | ANTI-MICROBIAL TOUCH PANEL AND METHOD OF MAKING SAME USING HOMEOTROPIC LIQUID CRYSTAL SILANES | 3M TOUCH SYSTEMS INC (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-1155352-A1 | ANTI-MICROBIAL TOUCH PANEL AND METHOD OF MAKING SAME USING HOMEOTROPIC LIQUID CRYSTAL SILANES | 3M Touch Systems, Inc. (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-1125163-A1 | SCRATCH RESISTANT DISPLAY AND METHOD OF MAKING SAME USING HOMEOTROPIC LIQUID CRYSTAL SILANES | Microtouch Systems, Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| US-20010013907-A1 | ANTI-MICROBIAL TOUCH PANEL AND METHOD OF MAKING SAME USING HOMEOTROPIC LIQUID CRYSTAL SILANES. | 3M INNOVATIVE PROPERTIES | 2001-08-16 | — | — | US | disclosed |
| WO-2000043831-A1 | ANTI-MICROBIAL TOUCH PANEL AND METHOD OF MAKING SAME USING HOMEOTROPIC LIQUID CRYSTAL SILANES | 3M TOUCH SYSTEMS, INC. (US) | 2000-07-27 | — | — | WO | disclosed |
| WO-2000020917-A1 | SCRATCH RESISTANT DISPLAY AND METHOD OF MAKING SAME USING HOMEOTROPIC LIQUID CRYSTAL SILANES | MICROTOUCH SYSTEMS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |