Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 known ✓ | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CACNA1B known ✓ | Q00975 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5325738 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MGLLHRH3CYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL3521843 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7930062 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MGLLHRH3CYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL11782028 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MGLLHRH3CYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL10651080 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MGLLHRH3CYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL844 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL8812637 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MGLLHRH3CYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL23277117 | 0.95 | ALDH1A1 (0.33) | ALDH1A1MGLLHRH3CYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL7749467 | 0.95 | ALDH1A1 (0.33) | ALDH1A1MGLLHRH3CYP2C9HPGD | |
| Bromide SCHEMBL8365933 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110393188-A | The purification process technique of glyphosate mother solution | LIU DELIANG | 2019-11-01 | — | — | CN | disclosed |
| CN-110396048-A | The comprehensive recovering process of glyphosate mother solution | LIU DELIANG | 2019-11-01 | — | — | CN | disclosed |
| CN-110393189-A | The comprehensive processing technique of glyphosate mother solution | LIU DELIANG | 2019-11-01 | — | — | CN | disclosed |
| CN-110396047-A | The recoverying and utilizing method of glyphosate mother solution | LIU DELIANG | 2019-11-01 | — | — | CN | disclosed |
| CN-109867608-A | A kind of process for cleanly preparing of glycine co-producing potassium chloride | 刘长飞 | 2019-06-11 | — | — | CN | disclosed |
| CN-208747977-U | A kind of equipment that glyphosate synthesis hydrolyzes in the process and recycles triethylamine | 湖北泰盛化工有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-106631945-B | The synthetic method of 3- (2- amino -2- thio-ethyls) methyl benzoate | 浙江大学 | 2018-09-07 | — | — | CN | disclosed |
| CN-108329349-A | A kind of glyphosate synthesis hydrolyzes and recycles in the process the device and method of triethylamine | 湖北泰盛化工有限公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-104478734-B | The method that in AKD production, crude product triethylamine recycles | 甘肃银光聚银化工有限公司 | 2016-09-14 | — | — | CN | disclosed |
| EP-2325278-B1 | Polycationic viscoelastic compositions | STEPAN CO (US) | 2015-09-09 | — | — | EP | disclosed |
| EP-2872508-A1 | IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SPRL (BE) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014009295-A1 | IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB PHARMA S.A. (BE) | 2014-01-16 | — | — | WO | disclosed |
| EP-1945734-A4 | POLYCATIONIC VISCOELASTIC COMPOSITIONS | STEPAN CO (US) | 2008-12-03 | — | — | EP | disclosed |
| US-20080255009-A1 | Quaternary ammonium compounds with two cationic sites connected through a linker; hydraulic fluids, demulsifiers, foamers, organoclays, thickeners, biocides, and oil field fluids. | STEPAN COMPANY | 2008-10-16 | — | — | US | disclosed |
| EP-1945734-A2 | POLYCATIONIC VISCOELASTIC COMPOSITIONS | STEPAN COMPANY (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056392-A9 | POLYCATIONIC VISCOELASTIC COMPOSITIONS | STEPAN CO (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007056284-A2 | POLYCATIONIC VISCOELASTIC COMPOSITIONS | STEPAN COMPANY (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056393-A2 | POLYCATIONIC VISCOELASTIC COMPOSITIONS | STEPAN COMPANY (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056392-A2 | POLYCATIONIC VISCOELASTIC COMPOSITIONS | STEPAN COMPANY (US) | 2007-05-18 | — | — | WO | disclosed |