Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28176837 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5741335 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL10373824 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28224283 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL27844031 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL27408294 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL27683341 | 0.95 | — | — | |
| SCHEMBL22434925 | 0.95 | — | — | |
| SCHEMBL18458273 | 0.95 | — | — | |
| SCHEMBL29868053 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107298655-A | 7,8 dimethoxy 2,3,4,5 tetrahydrochysene 1H benzos [c] azatropylidene hydrochloride and preparation method thereof | 郑州轻工业学院 | 2017-10-27 | — | — | CN | claimed |
| EP-1636217-B1 | 2-IMIDAZO-BENZOTHIAZOLES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2008-09-03 | — | — | EP | claimed |
| EP-1058551-A1 | USE OF D1/D5 ANTAGONISTS FOR TREATING OBSESSIVE COMPULSIVE DISORDERS, SOMATOFORM DISORDERS, DISSOCIATIVE DISORDERS, EATING DISORDERS, IMPULSE CONTROL DISORDERS AND AUTISM | SCHERING CORPORATION (US) | 2000-12-13 | — | — | EP | claimed |
| WO-1999044615-A1 | USE OF D1/D5 ANTAGONISTS FOR TREATING OBSESSIVE COMPULSIVE DISORDERS, SOMATOFORM DISORDERS, DISSOCIATIVE, EATING DISORDERS, IMPULSE CONTROL DISORDERS AND AUTISM | SCHERING CORPORATION (US) | 1999-09-10 | — | — | WO | claimed |
| CN-121204206-A | Method for checking microbial limit of azepine hydrochloride and application thereof | 江苏德迈药业有限公司 | 2025-12-26 | — | — | CN | disclosed |
| CN-120794911-A | Separation and purification method and application of azepine hydrochloride benzoyl hydrazone intermediate | 长风药业股份有限公司 | 2025-10-17 | — | — | CN | disclosed |
| CN-120682146-A | Salt forming method of azepine hydrochloride intermediate and application thereof | 长风药业股份有限公司 | 2025-09-23 | — | — | CN | disclosed |
| CN-120490332-A | Method for measuring benzalkonium chloride content in azepine hydrochloride nasal spray | 江苏德迈药业有限公司 | 2025-08-15 | — | — | CN | disclosed |
| CN-120189386-A | Azepine hydrochloride eye drops and preparation process thereof | 合肥华威药业有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-120189386-A | Azepine hydrochloride eye drops and preparation process thereof | 合肥华威药业有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-119176757-A | Preparation method of mianserin hydrochloride intermediate and derivative thereof | 四川青木制药有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-118001573-A | Drug delivery device with separable microneedles | 佐治亚科技研究公司 | 2024-05-10 | — | — | CN | disclosed |
| EP-0192034-A2 | Dibenzazepine derivatives, their preparation, starting materials for their preparation, and use of the dibenzazepine derivatives as pesticides | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | disclosed |
| EP-0058341-B1 | AZEPINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-05-15 | — | — | EP | disclosed |
| EP-0047412-B1 | PYRAZINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| EP-0035749-A1 | Heterocyclic compounds, their preparation and pharmaceutical compositions containing them | C.H. BOEHRINGER SOHN (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4049714-A | DIURETIC, ANTITHROMBOGENIC, ANTIARRYTHMIC, ANTIINFLAMMATORY, MUSCLE RELAXANTS | MEAD JOHNSON & COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-3979515-A | THYMOANALEPTIC ACTIVITY | ROUSSEL-UCLAF (FR) | 1976-09-07 | — | — | US | disclosed |
| US-3957757-A | THYMOANALEPTICS | ROUSSEL-UCLAF (FR) | 1976-05-18 | — | — | US | disclosed |
| US-3931151-A | ANTIDEPRESSANT, NEURO-SEDATIVE | ROUSSEL-UCLAF (FR) | 1976-01-06 | — | — | US | disclosed |