Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.77 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.74 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 4/20 | 0.67 |
| ▸ | HRH3 known ✓ | Q9Y5N1 | 1/20 | 0.67 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28037282 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL6113017 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL4618378 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL1072926 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL15821301 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL7264175 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL11907511 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL1109937 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL21253049 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL15822816 | 1.00 | MAOA (0.77) | MAOACHRM2LMNASIGMAR1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115228291-B | Anti-pollution, antibacterial and high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-115228291-A | Anti-pollution, antibacterial and large-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-110467537-B | Preparation process of L-p-hydroxyphenylglycine | 河南新天地药业股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-109536198-B | Catalytic gasoline sweetening activator and preparation method thereof | 安徽卓远化工科技有限公司 | 2020-10-30 | — | — | CN | claimed |
| CN-110467537-A | A kind of preparation process of D-HPG | HENAN NEWLAND PHARM CO LTD | 2019-11-19 | — | — | CN | claimed |
| CN-109536198-A | A kind of catalytic gasoline removal of mercaptans activator and its manufacturing method | 安徽卓远化工科技有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-106437817-B | It is a kind of to have the coal road filling colloidal materials and its application method for relapsing function | 华北科技学院 | 2019-01-04 | — | — | CN | claimed |
| CN-106437817-A | Coal road filling colloid material with reabsorption function and using method thereof | 华北科技学院 | 2017-02-22 | — | — | CN | claimed |
| CN-103215017-B | A kind of oil/gas drilling positive polarity borehole wall stabilizer and preparation method thereof | China Petroleum University (East China) (CN) | 2016-02-24 | — | — | CN | claimed |
| CN-103191745-B | Aromatic hydrocarbon hydrogenation catalyst | UNIV ANHUI TECHNOLOGY | 2014-09-10 | — | — | CN | claimed |
| CN-103215017-A | Electronpositive borehole wall stabilizer applied to oil and gas drilling and preparation method of electronpositive borehole wall stabilizer | UNIV CHINA PETROLEUM | 2013-07-24 | — | — | CN | claimed |
| CN-103191745-A | Aromatic hydrocarbon hydrogenation catalyst and preparation method thereof | UNIV ANHUI TECHNOLOGY | 2013-07-10 | — | — | CN | claimed |
| CN-101885801-B | Method for preparing nano compound temperature-sensitive hydrogel by using frontal polymerization technology | UNIV BEIJING SCIENCE & TECH | 2011-11-16 | — | — | CN | claimed |
| CN-101885801-A | Method for preparing nano compound temperature-sensitive hydrogel by using frontal polymerization technology | UNIV BEIJING SCIENCE & TECH | 2010-11-17 | — | — | CN | claimed |
| CN-1649994-A | Multi-component controlled delivery system for soap bars | SALVONA LLC (US) | 2005-08-03 | — | — | CN | claimed |
| CN-1144651-A | Ointment type consmetic composition, its preparation method and use | OREAL (FR) | 1997-03-12 | — | — | CN | claimed |
| CN-118829354-A | Compositions and methods for durable disinfection with mixed solvent systems | 法国特种经营公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-115228291-B | Anti-pollution, antibacterial and high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| US-4107099-A | RESIN CONTAINS CYANOBOROHYDRIDE COUNTER IONS | VENTRON CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4096311-A | POST-TREATMENT OF ADDING WATER AND SURVACTANT, WET-WORKING | SCOTT PAPER COMPANY (US) | 1978-06-20 | — | — | US | disclosed |