Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 known ✓ | Q12809 | 6/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27674229 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1KCNH2FAAH | |
| Hydrochloric Acid SCHEMBL11024823 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1KCNH2FAAH | |
| Hydrochloric Acid SCHEMBL6697664 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1KCNH2FAAH | |
| Hydrochloric Acid SCHEMBL10349387 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1KCNH2FAAH | |
| Hydrochloric Acid SCHEMBL11025594 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1KCNH2FAAH | |
| Hydrochloric Acid SCHEMBL11241631 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1KCNH2FAAH | |
| Hydrochloric Acid SCHEMBL28558208 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1KCNH2FAAH | |
| Hydrochloric Acid SCHEMBL28555076 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1KCNH2FAAH | |
| Hydrochloric Acid SCHEMBL10873473 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1KCNH2FAAH | |
| SCHEMBL4755851 | 0.98 | TSHR (0.48) | DNM1TSHRALDH1A1KCNH2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703865-A | Preparation method of temperature-resistant inverse emulsion polymer tackifying and cutting-off agent for drilling fluid | 中国石油天然气集团有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-109266058-B | Catalysis method and use method of water-based inorganic nano-coating | 湖南凯斯利新材料有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-109266058-A | A kind of catalysis process and application method of aqueous inorganic nano paint | 湖南凯斯利新材料有限公司 | 2019-01-25 | — | — | CN | claimed |
| CN-115703865-A | Preparation method of temperature-resistant inverse emulsion polymer tackifying and cutting-off agent for drilling fluid | 中国石油天然气集团有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-109266058-B | Catalysis method and use method of water-based inorganic nano-coating | 湖南凯斯利新材料有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-109266058-A | A kind of catalysis process and application method of aqueous inorganic nano paint | 湖南凯斯利新材料有限公司 | 2019-01-25 | — | — | CN | disclosed |
| EP-1841526-A2 | METHOD FOR THE PRODUCTION OF CATIONISED ADSORBENTS ABSORBENT MEANS OBTAINABLE THUS AND PREFERRED USE THEREOF | SÜD-CHEMIE AG (DE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077074-A2 | METHOD FOR THE PRODUCTION OF CATIONISED ADSORBENTS ABSORBENT MEANS OBTAINABLE THUS AND PREFERRED USE THEREOF | Süd-Chemie AG (DE) | 2006-07-27 | — | — | WO | disclosed |
| EP-0374196-A4 | METHOD OF REDUCING PITCH IN PULPING AND PAPERMAKING | — | 1991-03-20 | — | — | EP | disclosed |
| US-4964955-A | ADDING WATER SOLUBLE CATIONIC POLYMER ADSORBED ONTO WATER INSOLUBLE PARTICULATE SUBSTRATE, ADSORBING PITCH ONTO COMPOSITE | CYPRUS MINES CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0374196-A1 | METHOD OF REDUCING PITCH IN PULPING AND PAPERMAKING | CYPRUS INDUSTRIAL MINERALS COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4156628-A | TREATMENT WITH CATIONIC AND ANIONIC WATER-SOLUBLE, NITROGEN-CONTAINING POLYMERS | HERCULES INCORPORATED (US) | 1979-05-29 | — | — | US | disclosed |
| US-4154646-A | TREATMENT WITH AQUEOUS MIXTURE OF CATIONIC AND ANIONIC WATER-SOLUBLE NITROGEN-CONTAINING POLYMERS | HERCULES INCORPORATED (US) | 1979-05-15 | — | — | US | disclosed |
| US-4109053-A | SIZING PAPER WITH STABLE DISPERSIONS OF HYDROCARBON RESINS | HERCULES INCORPORATED (US) | 1978-08-22 | — | — | US | disclosed |
| US-4017431-A | Aqueous dispersions of wax blends and a water-soluble cationic resin and paper sized therewith | HERCULES INCORPORATED (US) | 1977-04-12 | — | — | US | disclosed |
| US-3966684-A | RETENTION AIDS FOR PAPER FILLERS | HERCULES INCORPORATED (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966654-A | CATIONIC AMINOPOLYAMIDE-EPICHLOROHYDRIN RESIN | HERCULES INCORPORATED (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966694-A | RETENTION AIDS FOR PAPER FILLERS | HERCULES INCORPORATED (US) | 1976-06-29 | — | — | US | disclosed |
| US-3951921-A | PAPER FILLERS | HERCULES INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |
| US-3941736-A | Stable aqueous dispersions of hydrocarbon resins and water soluble polyaminopolyamide-epichlorohydrin resin as dispersing agent | HERCULES INCORPORATED (US) | 1976-03-02 | — | — | US | disclosed |