Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL5490292 | 1.00 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNATDP1 | |
| Acrylamide SCHEMBL27932443 | 0.97 | ALDH1A1 (0.65) | ALDH1A1TSHRFGFR4LMNATDP1 | |
| Acrylamide SCHEMBL27932442 | 0.97 | ALDH1A1 (0.65) | ALDH1A1TSHRFGFR4LMNATDP1 | |
| Acrylamide SCHEMBL8103524 | 0.97 | — | — | |
| Acrylamide SCHEMBL27538123 | 0.91 | ALDH1A1 (0.65) | ALDH1A1TSHRFGFR4LMNATDP1 | |
| Acrylamide SCHEMBL28037683 | 0.87 | — | — | |
| Acrylamide SCHEMBL5739810 | 0.87 | — | — | |
| Acrylamide SCHEMBL332483 | 0.87 | — | — | |
| Acrylamide SCHEMBL2515155 | 0.87 | — | — | |
| Acrylamide SCHEMBL27857124 | 0.86 | TSHR (0.58) | ALDH1A1TSHRFGFR4LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112473389-B | Reverse osmosis membrane repairing agent and reverse osmosis membrane off-line repairing method | 天津市尚拓环保科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-112473389-A | Reverse osmosis membrane repairing agent and reverse osmosis membrane off-line repairing method | 天津市尚拓环保科技有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-115433423-B | Water-absorbing polymer with anti-caking, whiteness improving, deodorizing and bacteriostasis effects, and manufacturing method and application thereof | 台湾塑胶工业股份有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-112473389-B | Reverse osmosis membrane repairing agent and reverse osmosis membrane off-line repairing method | 天津市尚拓环保科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-112473389-B | Reverse osmosis membrane repairing agent and reverse osmosis membrane off-line repairing method | 天津市尚拓环保科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| EP-3381972-B1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | FORMOSA PLASTICS CORP (TW) | 2021-07-07 | — | — | EP | disclosed |
| CN-112473389-A | Reverse osmosis membrane repairing agent and reverse osmosis membrane off-line repairing method | 天津市尚拓环保科技有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-112473389-A | Reverse osmosis membrane repairing agent and reverse osmosis membrane off-line repairing method | 天津市尚拓环保科技有限公司 | 2021-03-12 | — | — | CN | disclosed |
| US-10731024-B2 | Superabsorbent polymer and the method of fabricating the same | FORMOSA PLASTICS CORPORATION (TW) | 2020-08-04 | — | — | US | disclosed |
| US-10550243-B2 | Superabsorbent polymer and the method of fabricating the same | FORMOSA PLASTICS CORPORATION (TW) | 2020-02-04 | — | — | US | disclosed |
| CN-106068284-B | Derivative cationic copolymer aqueous solution of acrylamide and its preparation method and application | S P C M 股份公司 | 2019-06-14 | — | — | CN | disclosed |
| US-20180282515-A1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | FORMOSA PLASTICS CORPORATION (TW) | 2018-10-04 | — | — | US | disclosed |
| EP-3381972-A1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | Formosa Plastics Corporation (TW) | 2018-10-03 | — | — | EP | disclosed |
| CN-106467600-A | A kind of friction reducer for slippery water fracturing fluid and preparation method thereof | 中国石油化工股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-106068284-A | Acrylamide derives cation copolymer aqueous solution and its production and use | S.P.C.M.公司 | 2016-11-02 | — | — | CN | disclosed |
| CN-101861342-A | High definition printing with waterborne inks on non-porous substrates | RHODIA | 2010-10-13 | — | — | CN | disclosed |
| US-7169444-B2 | Method for treating surface of ink jet recording medium having recorded image | SEIKO EPSON CORPORATION (JP) | 2007-01-30 | — | — | US | disclosed |
| CN-1549701-A | Deodorant composition | — | 2004-11-24 | — | — | CN | disclosed |
| US-20030005945-A1 | Method for surface-treatment, surface-treated article and device for surface treatment | SEIKO EPSON CORPORATION (JP) | 2003-01-09 | — | — | US | disclosed |
| EP-1186439-A1 | METHOD FOR SURFACE TREATMENT, SURFACE-TREATED ARTICLE AND DEVICE FOR SURFACE TREATMENT | SEIKO EPSON CORPORATION (JP) | 2002-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550243-B2 | Superabsorbent polymer and the method of fabricating the same | STOM, SAP18, PCNA | ALDH1A1 2316/4885TSHR 4000/4885FGFR4 4334/4885 |
| US-20180282515-A1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | STOM, SAP18, PCNA | ALDH1A1 2316/4885TSHR 4000/4885FGFR4 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.