Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30248 | 0.98 | — | — | |
| SCHEMBL4757408 | 0.80 | — | — | |
| Benzothiophene SCHEMBL10671323 | 0.77 | CTNNB1 (0.33) | — | |
| SCHEMBL6224411 | 0.69 | — | — | |
| SCHEMBL16466271 | 0.66 | CA2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL27832467 | 0.65 | POLB (0.30) | — | |
| Hydrochloric Acid SCHEMBL28208398 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL28207816 | 0.64 | — | — | |
| SCHEMBL6542443 | 0.63 | — | — | |
| SCHEMBL3707107 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024794-B1 | Methods of treating capsules and dry, powdered pharmaceutical formulations | BOEHRINGER INGELHEIM PHARMA (US) | 2007-01-03 | — | — | EP | claimed |
| CN-104703584-B | Inhalable pharmaceutical compositions | 艾塞尤提卡控股公司 | 2019-05-31 | — | — | CN | disclosed |
| US-20180318170-A1 | Inhalable Pharmaceutical Compositions | ICEUTICA PTY LTD. (AU) | 2018-11-08 | — | — | US | disclosed |
| US-10022303-B2 | Inhalable pharmaceutical compositions | ICEUTICA PTY LTD. (AU) | 2018-07-17 | — | — | US | disclosed |
| CN-107875127-A | Inhalable drug composition | 艾塞尤提卡控股公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-104703584-A | Inhalable pharmaceutical compositions | ICEUTICA HOLDINGS INC BVI | 2015-06-10 | — | — | CN | disclosed |
| EP-2819645-A2 | INHALABLE PHARMACEUTICAL COMPOSITIONS | Iceutica Holdings Inc. Bvi (VG) | 2015-01-07 | — | — | EP | disclosed |
| US-20140065219-A1 | Inhalable Pharmaceutical Compositions | ICEUTICA PTY LTD. | 2014-03-06 | — | — | US | disclosed |
| WO-2013128283-A2 | INHALABLE PHARMACEUTICAL COMPOSITIONS | ICEUTICA HOLDINGS INC. BVI (VG) | 2013-09-06 | — | — | WO | disclosed |
| EP-1024794-B1 | Methods of treating capsules and dry, powdered pharmaceutical formulations | BOEHRINGER INGELHEIM PHARMA (US) | 2007-01-03 | — | — | EP | disclosed |
| US-5376386-A | Crystalline particulate saccharide carrier for dry powder inhalers having specified particle size and rugosity | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-12-27 | — | — | US | disclosed |
| EP-0464171-B1 | AEROSOL CARRIERS | BRITISH TECH GROUP (GB) | 1993-12-15 | — | — | EP | disclosed |
| US-5254330-A | Dry powder inhalant of non-proteinaceous pharmacological agent mixed with carrier particles of specific size and rugosity | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1993-10-19 | — | — | US | disclosed |
| EP-0258356-B1 | NEW PHARMACEUTICAL COMPOSITIONS FOR INHALATION | CHIESI FARMACEUTICI S.p.A. (IT) | 1993-09-22 | — | — | EP | disclosed |
| EP-0464171-A1 | AEROSOL CARRIERS. | NAT RES DEV (GB) | 1992-01-08 | — | — | EP | disclosed |
| WO-1991011179-A1 | AEROSOL CARRIERS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-08-08 | — | — | WO | disclosed |
| EP-0239798-B1 | NEW PHARMACEUTICAL COMPOSITIONS FOR INHALATION | CHIESI FARMACEUTICI S.p.A. (IT) | 1990-09-26 | — | — | EP | disclosed |
| EP-0258356-A1 | NEW PHARMACEUTICAL COMPOSITIONS FOR INHALATION. | CHIESI FARMA SPA (IT) | 1988-03-09 | — | — | EP | disclosed |
| EP-0239798-A1 | New pharmaceutical compositions for inhalation | CHIESI FARMACEUTICI S.p.A. (IT) | 1987-10-07 | — | — | EP | disclosed |
| WO-1987005213-A1 | NEW PHARMACEUTICAL COMPOSITIONS FOR INHALATION | CHIESI FARMACEUTICI S.P.A. (IT) | 1987-09-11 | — | — | WO | disclosed |