Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 known ✓ | P11387 | 4/20 | 0.53 |
| ▸ | TERT | O14746 | 4/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | CYCS | P99999 | 4/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15768782 | 0.98 | TERT (0.55) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL22265228 | 0.98 | TERT (0.55) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL29414382 | 0.97 | TERT (0.57) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL949511 | 0.97 | TERT (0.57) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL2338257 | 0.95 | TERT (0.55) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL30539978 | 0.95 | TERT (0.55) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL20856304 | 0.95 | TERT (0.59) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL29515314 | 0.95 | TERT (0.55) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL8430292 | 0.95 | TERT (0.55) | TERTABCG2TOP1CYCSENPP2 | |
| SCHEMBL29431119 | 0.95 | TERT (0.55) | TERTABCG2TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106290631-B | A kind of method of pigment array sensing technology Fast Evaluation magma Quality of Liquors | 江苏今世缘酒业股份有限公司 | 2018-11-27 | — | — | CN | claimed |
| CN-106290631-A | A kind of method of pigment array sensing technology Fast Evaluation original plasm wine quality | 江苏今世缘酒业股份有限公司 | 2017-01-04 | — | — | CN | claimed |
| EP-2602655-B1 | Ophthalmic filter | ESSILOR INT (FR) | 2024-04-03 | — | — | EP | disclosed |
| US-11635547-B2 | Composition for the manufacture of an ophthalmic lens comprising an encapsulated light-absorbing additive | ESSILOR INTERNATIONAL (FR) | 2023-04-25 | — | — | US | disclosed |
| EP-2602654-B1 | Ophthalmic filter | ESSILOR INT (FR) | 2023-04-19 | — | — | EP | disclosed |
| EP-3497488-B2 | OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE | ESSILOR INT (FR) | 2023-03-22 | — | — | EP | disclosed |
| US-11327202-B2 | Composition for the manufacture of an ophthalmic lens comprising an encapsulated light-absorbing additive | ESSILOR INTERNATIONAL (FR) | 2022-05-10 | — | — | US | disclosed |
| US-20200386913-A1 | Composition for the Manufacture of an Ophthalmic Lens Comprising an Encapsulated Light-Absorbing Additive | ESSILOR INTERNATIONAL (FR) | 2020-12-10 | — | — | US | disclosed |
| EP-2602653-B1 | Method of determining the configuration of an ophthalmic filter | ESSILOR INT (FR) | 2020-09-16 | — | — | EP | disclosed |
| EP-3495853-B1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE | ESSILOR INT (FR) | 2020-07-29 | — | — | EP | disclosed |
| EP-3497488-B1 | OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE | ESSILOR INT (FR) | 2020-06-17 | — | — | EP | disclosed |
| CN-106290631-A | A kind of method of pigment array sensing technology Fast Evaluation original plasm wine quality | 江苏今世缘酒业股份有限公司 | 2017-01-04 | — | — | CN | disclosed |
| US-20150002809-A1 | OPHTHALMIC FILTER | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2015-01-01 | — | — | US | disclosed |
| US-20140320806-A1 | METHOD OF DETERMINING THE CONFIGURATION OF AN OPHTHALMIC FILTER | UNIVERSITE PARIS 6 PIERRE ET MARIE CURIE (FR) | 2014-10-30 | — | — | US | disclosed |
| US-20140300857-A1 | OPHTHALMIC FILTER | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQU E) (FR) | 2014-10-09 | — | — | US | disclosed |
| EP-2602655-A1 | Ophthalmic filter | Essilor International (Compagnie Générale D'Optique) (FR) | 2013-06-12 | — | — | EP | disclosed |
| EP-2602654-A1 | Ophthalmic filter | Essilor International (Compagnie Générale D'Optique) (FR) | 2013-06-12 | — | — | EP | disclosed |
| EP-2602653-A1 | Method of determining the configuration of an ophthalmic filter | Essilor International (Compagnie Générale D'Optique) (FR) | 2013-06-12 | — | — | EP | disclosed |
| EP-1704057-A1 | LASER IMAGING | Sherwood Technology LTD. (GB) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005068207-A1 | LASER IMAGING | DATALASE LTD. (GB) | 2005-07-28 | — | — | WO | disclosed |