Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.42 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.38 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.38 |
| ▸ | KCNH3 known ✓ | Q9ULD8 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8922354 | 1.00 | NAAA (0.42) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL93430 | 0.98 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Water SCHEMBL569222 | 0.98 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL29054346 | 0.98 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL1845659 | 0.98 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL755158 | 0.98 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6803724 | 0.98 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL97019 | 0.98 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Water SCHEMBL6896532 | 0.98 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL29054370 | 0.98 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2939764-A1 | METHOD FOR MANUFACTURING HOLLOW METAL NANOPARTICLE SUPPORTED BY SUPPORT BODY | LG Chem, Ltd. (KR) | 2015-11-04 | — | — | EP | claimed |
| WO-2006062926-A1 | METHODS FOR PREPARING SKIN FOR BIOMETRIC IMAGE ACQUISITION | APRILIS, INC. (US) | 2006-06-15 | — | — | WO | claimed |
| US-10975331-B2 | Viscoelastic amphoteric surfactant based composition for increasing oil well production | ECOLAB USA INC. (US) | 2021-04-13 | — | — | US | disclosed |
| CN-111093694-A | Chlamydia nanoemulsion vaccine | 纳诺碧欧公司 | 2020-05-01 | — | — | CN | disclosed |
| US-20190177657-A1 | VISCOELASTIC AMPHOTERIC SURFACTANT BASED CLEANING COMPOSITIONS | ECOLAB USA INC. | 2019-06-13 | — | — | US | disclosed |
| US-10246665-B2 | Viscoelastic amphoteric surfactant based cleaning compositions | ECOLAB USA INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-10100268-B2 | Acidic viscoelastic surfactant-based cleaning compositions with an alkali metal salt pseudo-linker | ECOLAB USA INC. (US) | 2018-10-16 | — | — | US | disclosed |
| EP-2939764-B1 | METHOD FOR MANUFACTURING HOLLOW METAL NANOPARTICLE SUPPORTED BY SUPPORT BODY | LG CHEMICAL LTD (KR) | 2018-09-26 | — | — | EP | disclosed |
| US-20180010069-A1 | ACIDIC VISCOELASTIC SURFACTANT BASED CLEANING COMPOSITIONS | ECOLAB USA INC. | 2018-01-11 | — | — | US | disclosed |
| US-20170335241-A1 | VISCOELASTIC AMPHOTERIC SURFACTANT BASED CLEANING COMPOSITIONS | ECOLAB USA INC. | 2017-11-23 | — | — | US | disclosed |
| US-9765284-B2 | Viscoelastic amphoteric surfactant based cleaning compositions | ECOLAB USA INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-6846793-B1 | Cleaning concentrate | ECOLAB, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| WO-2004094579-A1 | CLEANING CONCENTRATE | ECOLAB INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| US-6767881-B1 | COMPOSITION COMPRISING TERPENE COMPOUND, SURFACTANT, AND ETHOXYLATED ARYL ALCOHOL | ECOLAB, INC. | 2004-07-27 | — | — | US | disclosed |
| US-20040122112-A1 | Non-surfactant solubilizing agent | ECOLAB USA INC. | 2004-06-24 | — | — | US | disclosed |
| WO-2004031336-A1 | NON-POLYMER THICKENING AGENT AND CLEANING COMPOSITION | ECOLAB INC. (US) | 2004-04-15 | — | — | WO | disclosed |
| US-20040067866-A1 | Non-polymer thickening agent and cleaning composition | ECOLAB, INC. | 2004-04-08 | — | — | US | disclosed |
| WO-2004022687-A1 | NON-SURFACTANT SOLUBILIZING AGENT | ECOLAB INC. (US) | 2004-03-18 | — | — | WO | disclosed |
| US-20040026665-A1 | Non-surfactant solubilizing agent | ECOLAB USA INC. | 2004-02-12 | — | — | US | disclosed |
| WO-2004011587-A1 | CLEANER/DEGREASER COMPOSITIONS COMPRISING NON-SURFACTANT SOLUBILIZING AGENT | ECOLAB INC (US) | 2004-02-05 | — | — | WO | disclosed |