Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 4-Dimethylaminophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.50 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.48 |
| ▸ | ADRA2B known ✓ | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C known ✓ | P18825 | 2/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | HBB | P68871 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Dimethylaminophenol SCHEMBL9792507 | 0.97 | APP (0.73) | APPALDH1A1TSHRALOX15HSD17B10 | |
| 4-Dimethylaminophenol SCHEMBL224308 | 0.97 | APP (0.73) | APPALDH1A1TSHRALOX15HSD17B10 | |
| 4-Dimethylaminophenol SCHEMBL29143506 | 0.94 | APP (0.70) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL5531187 | 0.89 | APP (0.69) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL28344492 | 0.89 | APP (0.64) | APPALDH1A1TSHRALOX15HSD17B10 | |
| 4-Dimethylaminophenol SCHEMBL23467138 | 0.87 | APP (0.61) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL11738417 | 0.86 | APP (0.55) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL6338004 | 0.85 | APP (0.59) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL379126 | 0.84 | ALDH1A1 (0.92) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL2443748 | 0.84 | ALDH1A1 (0.92) | APPALDH1A1TSHRALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619835-A | Preparation method of p-dimethylaminophenol and hydrochloride thereof | 上海凌凯科技股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-115808477-B | Method for measuring free 3-chloro-1, 2-propanediol and glycidol in fish oil and shrimp oil dietary supplements | 中国水产科学研究院东海水产研究所 | 2023-09-01 | — | — | CN | claimed |
| CN-115808477-A | Method for determining free 3-chloro-1, 2-propanediol and glycidol in fish oil and shrimp oil dietary supplement | 中国水产科学研究院东海水产研究所 | 2023-03-17 | — | — | CN | claimed |
| CN-110016008-B | Fluorescent probe for specifically recognizing hydrogen polysulfide and biological thiol | 南宁师范大学 | 2022-04-15 | — | — | CN | claimed |
| US-4517005-A | Aminophenol urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-14 | — | — | US | claimed |
| EP-0051163-A2 | A 4-dimethylaminophenol-hydrochloride solution for painless intramuscular administration, and process for its preparation | Dr. Franz Köhler Chemie KG (DE) | 1982-05-12 | — | — | EP | claimed |
| US-3970459-A | Process for developing a direct reversal silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-20 | — | — | US | claimed |
| US-20250303393-A1 | LIQUID CONTAMINANT ABSORBENT AND A METHOD FOR FABRICATING A LIQUID CONTAMINANT ABSORBENT | THE UNIVERSITY OF HONG KONG (CN) | 2025-10-02 | — | — | US | disclosed |
| CN-119395182-A | Method for detecting 2-chloro-propanediol and 3-chloro-propanediol | 上海应用技术大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-118619835-A | Preparation method of p-dimethylaminophenol and hydrochloride thereof | 上海凌凯科技股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-117088905-A | Asymmetric boron-fluorine pyrrole fluorescent dye, preparation method thereof and method for preparing fluorescent microspheres | 南京珀立科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117079912-A | Polymer-based dielectric and preparation method thereof | 广州大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-115808477-B | Method for measuring free 3-chloro-1, 2-propanediol and glycidol in fish oil and shrimp oil dietary supplements | 中国水产科学研究院东海水产研究所 | 2023-09-01 | — | — | CN | disclosed |
| EP-0051163-A2 | A 4-dimethylaminophenol-hydrochloride solution for painless intramuscular administration, and process for its preparation | Dr. Franz Köhler Chemie KG (DE) | 1982-05-12 | — | — | EP | disclosed |
| EP-0051163-A2 | A 4-dimethylaminophenol-hydrochloride solution for painless intramuscular administration, and process for its preparation | Dr. Franz Köhler Chemie KG (DE) | 1982-05-12 | — | — | EP | disclosed |
| EP-0051163-A2 | A 4-dimethylaminophenol-hydrochloride solution for painless intramuscular administration, and process for its preparation | Dr. Franz Köhler Chemie KG (DE) | 1982-05-12 | — | — | EP | disclosed |
| US-4223036-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-09-16 | — | — | US | disclosed |
| US-4144346-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-03-13 | — | — | US | disclosed |
| US-4002480-A | CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-11 | — | — | US | disclosed |
| US-3970459-A | Process for developing a direct reversal silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-20 | — | — | US | disclosed |