Hydrochloric Acid

Hydrochloric Acid

SCHEMBL628183

Cl.Cl.O=C(O)c1cccc(-c2ccccc2)c1C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB4 known ✓ P30926 1/20 0.46
CHRNA3 known ✓ P32297 1/20 0.46
CA2 known ✓ P00918 1/20 0.43
HNF4A P41235 1/20 0.63
FABP3 P05413 1/20 0.53
FABP4 P15090 1/20 0.53
FABP5 Q01469 1/20 0.53
FOLH1 Q04609 2/20 0.53
BCAT2 O15382 1/20 0.52
ALDH1A1 P00352 4/20 0.50
ALOX15 P16050 1/20 0.50
CDC25B P30305 2/20 0.48
ATM Q13315 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
MYC P01106 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL993304 1.00 HNF4A (0.63) HNF4AFABP3FABP4FABP5FOLH1
SCHEMBL29376910 0.98 HNF4A (0.66) HNF4AFABP3FABP4FABP5FOLH1
SCHEMBL36146 0.98 HNF4A (0.66) HNF4AFABP3FABP4FABP5FOLH1
SCHEMBL28558290 0.96 HNF4A (0.63) HNF4AFABP3FABP4FABP5FOLH1
SCHEMBL6666734 0.96 HNF4A (0.63) HNF4AFABP3FABP4FABP5FOLH1
SCHEMBL2833055 0.96 HNF4A (0.63) HNF4AFABP3FABP4FABP5FOLH1
SCHEMBL6661257 0.96 HNF4A (0.63) HNF4AFABP3FABP4FABP5FOLH1
SCHEMBL6662914 0.96 HNF4A (0.63) HNF4AFABP3FABP4FABP5FOLH1
Methane SCHEMBL28932446 0.96 HNF4A (0.63) HNF4AFABP3FABP4FABP5FOLH1
Bromide SCHEMBL8757513 0.96 HNF4A (0.63) HNF4AFABP3FABP4FABP5FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118949709-A Composite nanofiltration membrane, preparation method and application thereof in phosphoric acid purification 华中科技大学 2024-11-15 CN claimed
CN-115583834-B High-performance aramid-based graphite film and preparation method thereof 浙江中科玖源新材料有限公司 2024-02-20 CN claimed
CN-115845615-A High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof 万华化学集团股份有限公司 2023-03-28 CN claimed
CN-111632498-A Preparation method of non-woven fabric substrate supported polyethylene nanofiltration membrane 上海恩捷新材料科技有限公司 2020-09-08 CN claimed
JP-5320093-A None JP disclosed
EP-4176962-B1 COMPOSITE SEMIPERMEABLE MEMBRANE, SPIRAL MEMBRANE ELEMENT, WATER TREATMENT SYSTEM, AND WATER TREATMENT METHOD NITTO DENKO CORP (JP) 2026-01-28 EP disclosed
US-20250352957-A1 COMPOSITE SEMIPERMEABLE MEMBRANE AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES, INC. (JP) 2025-11-20 US disclosed
EP-4023326-B1 GAS SEPARATION MEMBRANE MODULE TORAY INDUSTRIES (JP) 2025-11-05 EP disclosed
EP-4640306-A1 PROCESSING METHOD FOR POLYAMIDE-BASED SEMIPERMEABLE MEMBRANE, PRODUCTION METHOD AND PROCESSING APPARATUS FOR SEMIPERMEABLE MEMBRANE ELEMENT, AND FLUID PROCESSING METHOD AND FLUID PROCESSING APPARATUS EACH USING SEMIPERMEABLE MEMBRANE ELEMENT Toray Industries, Inc. (JP) 2025-10-29 EP disclosed
EP-4631607-A1 COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL-TYPE MEMBRANE ELEMENT Nitto Denko Corporation (JP) 2025-10-15 EP disclosed
US-12434202-B2 Composite semipermeable membrane TORAY INDUSTRIES, INC. (JP) 2025-10-07 US disclosed
EP-4424409-B1 COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL MEMBRANE ELEMENT NITTO DENKO CORP (JP) 2025-08-20 EP disclosed
EP-0154506-B1 PREPARATION OF ORGANIC POLYMERS RAYCHEM LIMITED (GB) 1992-02-05 EP disclosed
US-5084549-A Aromatic polyesters as thermoplastic molding materials BAYER AKTIENGESELLSCHAFT (DE) 1992-01-28 US disclosed
US-4999411-A Polythioethers, polythiocarbonates, polythioamides, polythioimides RAYCHEM LIMITED (GB) 1991-03-12 US disclosed
US-4960835-A ENGINEERING THERMOPLASTICS RAYCHEM LIMITED (GB) 1990-10-02 US disclosed
EP-0361843-A2 Chiral smectic C liquid crystalline polyester NIPPON OIL CO., LTD. (JP) 1990-04-04 EP disclosed
US-4845179-A CONDENSATION POLYMERIZATION RAYCHEM LIMITED (GB) 1989-07-04 US disclosed
EP-0154506-A2 Preparation of organic polymers RAYCHEM LIMITED (GB) 1985-09-11 EP disclosed
US-4172938-A Process for producing polyamides with lactam or urea solvent and CaCl2 TEIJIN LIMITED (JP) 1979-10-30 US disclosed