Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.47 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL201139 | 1.00 | DNM1 (0.48) | DNM1CA12CA1CA2CA3 | |
| Hydrochloric Acid SCHEMBL11235335 | 1.00 | DNM1 (0.48) | DNM1CA12CA1CA2CA3 | |
| Hydrochloric Acid SCHEMBL27875030 | 1.00 | DNM1 (0.48) | DNM1CA12CA1CA2CA3 | |
| Hydrochloric Acid SCHEMBL10361508 | 1.00 | DNM1 (0.48) | DNM1CA12CA1CA2CA3 | |
| Hydrochloric Acid SCHEMBL2746193 | 1.00 | DNM1 (0.48) | DNM1CA12CA1CA2CA3 | |
| Bromide SCHEMBL3093297 | 0.97 | DNM1 (0.46) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL2745741 | 0.97 | DNM1 (0.50) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL11413710 | 0.97 | DNM1 (0.50) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL6050226 | 0.97 | DNM1 (0.50) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL13893474 | 0.97 | DNM1 (0.50) | DNM1CA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109680283-A | Magnesium alloy cleaning agent and its cleaning method | 惠州市阿特斯润滑技术有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-103510100-B | metal cleaning agent | 大连三星五洲化工有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-108914547-A | The slashing technique of cotton-polyester blend fabric yarn | 南通晗奥纺织有限公司 | 2018-11-30 | — | — | CN | claimed |
| CN-108086004-A | A kind of waterproof fireproofing fabric manufacture craft | 海宁市金义服饰有限公司 | 2018-05-29 | — | — | CN | claimed |
| CN-107879604-A | The bending method of glass | 太仓经济开发区蕴源吉光工艺美术品工作室 | 2018-04-06 | — | — | CN | claimed |
| CN-107641240-A | A kind of PE packing films | 安徽明诚塑业有限公司 | 2018-01-30 | — | — | CN | claimed |
| CN-107383562-A | One kind is packed for PE films | 安徽天大环保新材料股份有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-107236301-A | PPS PC short glass fiber high molecule alloy materials and preparation method thereof | 苏州市慧通塑胶有限公司 | 2017-10-10 | — | — | CN | claimed |
| CN-106589708-A | Antibacterial plastics for toys and preparation method for antibacterial plastics | 郑州掌盟网络科技有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-106479090-A | A kind of toy antibiotic plastic and preparation method thereof | 郑州诚合信息技术有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-102089319-A | Protein reforming method | AJINOMOTO KK | 2011-06-08 | — | — | CN | claimed |
| CN-101056695-B | Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and treatment method for boron-containing water using the same | TORAY INDUSTRIES | 2011-01-26 | — | — | CN | claimed |
| CN-1639311-B | Mixtures of quaternary compounds | CRODA INC | 2010-05-12 | — | — | CN | claimed |
| CN-101641474-A | Film material with antimicrobial and/or odor-absorbing coating and sanitary article | NUOVA PANSAC S P A IT | 2010-02-03 | — | — | CN | claimed |
| CN-101500540-A | Nanoparticulate kinase inhibitor formulations | ELAN PHARMA INT LTD (IE) | 2009-08-05 | — | — | CN | claimed |
| CN-1084474-C | Agent for analysing leucocyte and classification of leucocyte | SYSMEX CORP (JP) | 2002-05-08 | — | — | CN | claimed |
| CN-1084473-C | Reagent for analysing leucocyte | SYSMEX CORP (JP) | 2002-05-08 | — | — | CN | claimed |
| CN-1040469-C | A pretreatment method for blood analysis | EAST ASIA MED ELECTRONICS (JP) | 1998-10-28 | — | — | CN | claimed |
| CN-1092172-A | The preprocess method that is used for blood analysis | EAST ASIA MED ELECTRONICS (JP) | 1994-09-14 | — | — | CN | claimed |
| US-4122119-A | Process for the production of unsaturated ketones | KURARAY CO., LTD. (JP) | 1978-10-24 | — | — | US | claimed |