Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.45 |
| ▸ | CHRNA7 known ✓ | P36544 | 1/20 | 0.45 |
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28002009 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1DNM1CHRM2 | |
| Hydrochloric Acid SCHEMBL11250021 | 0.98 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1DNM1CHRM2 | |
| Hydrochloric Acid SCHEMBL27558569 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1DNM1CHRM2 | |
| Hydrochloric Acid SCHEMBL11567891 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1DNM1CHRM2 | |
| Hydrochloric Acid SCHEMBL11567887 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1DNM1CHRM2 | |
| SCHEMBL130071 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1DNM1CHRM2 | |
| Hydrochloric Acid SCHEMBL27558568 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1DNM1CHRM2 | |
| Fluoride Ion SCHEMBL6316238 | 0.96 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1DNM1CHRM2 | |
| Water SCHEMBL2110702 | 0.96 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1DNM1CHRM2 | |
| SCHEMBL16781188 | 0.96 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1DNM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240148627-A1 | GERMICIDAL FOAM FOR THE SKIN | CARRANZA LOPEZ TZINTZUN (MX) | 2024-05-09 | — | — | US | claimed |
| US-12161973-B2 | Filtering device, purification device, and method for manufacturing chemical liquid | FUJIFILM CORPORATION (JP) | 2024-12-10 | — | — | US | disclosed |
| US-20240148627-A1 | GERMICIDAL FOAM FOR THE SKIN | CARRANZA LOPEZ TZINTZUN (MX) | 2024-05-09 | — | — | US | disclosed |
| US-20240050898-A1 | FILTERING DEVICE, PURIFICATION DEVICE, AND METHOD FOR MANUFACTURING CHEMICAL LIQUID | FUJIFILM CORPORATION (JP) | 2024-02-15 | — | — | US | disclosed |
| US-11833475-B2 | Filtering device, purification device, and method for manufacturing chemical liquid | FUJIFILM CORPORATION (JP) | 2023-12-05 | — | — | US | disclosed |
| US-20200368691-A1 | FILTERING DEVICE, PURIFICATION DEVICE, AND METHOD FOR MANUFACTURING CHEMICAL LIQUID | FUJIFILM CORPORATION (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-0988348-B1 | INTERIOR TEXTURED COATING REMOVER COMPOSITION | MOGRIDGE ITHIEL (GB) | 2004-09-01 | — | — | EP | disclosed |
| US-6635608-B1 | Alkoxyether and alcohol solvents with amine or amide having carboxylic or sulfonic functionality; removing asbestos fiber containing coatings; suppresses dust; nonirritating; does not damage plaster | MOGRIDGE ITHIEL (GB) | 2003-10-21 | — | — | US | disclosed |
| US-6632782-B1 | Water and alkoxy ether solvents containing lower alcohol and blend of surfactants; noncorrosive; nonirritating; no harmful or obnoxious vapors; nondamaging to wood or plaster; effective on water and oil based compositions | MOGRIDGE ITHIEL (GB) | 2003-10-14 | — | — | US | disclosed |
| EP-0925335-B1 | PAINT REMOVING COMPOSITIONS | MOGRIDGE ITHIEL (GB) | 2002-11-06 | — | — | EP | disclosed |
| US-6221395-B1 | POORLY SOLUBLE IN WATER ACTIVE PRINCIPLE (ES: NIFEDIPINE) IS TREATED WITH A SODIUM LAURYL SULFATE SURFACTANT AND HYDROXYPROPYL METHYL CELLULOSE; HIGH BIOAVAILABILITY | JAGOTEC AG (CH) | 2001-04-24 | — | — | US | disclosed |
| EP-0988348-A1 | INTERIOR TEXTURED COATING REMOVER COMPOSITION | Mogridge, Ithiel (GB) | 2000-03-29 | — | — | EP | disclosed |
| EP-0925335-A1 | PAINT REMOVING COMPOSITIONS | Mogridge, Ithiel (GB) | 1999-06-30 | — | — | EP | disclosed |
| WO-1999001515-A1 | PAINT REMOVING COMPOSITIONS | MOGRIDGE ITHIEL (GB) | 1999-01-14 | — | — | WO | disclosed |
| WO-1998056864-A1 | INTERIOR TEXTURED COATING REMOVER COMPOSITION | MOGRIDGE ITHIEL (GB) | 1998-12-17 | — | — | WO | disclosed |