Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methyl Isobutyl Ketone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Isobutyl Ketone SCHEMBL28109876 | 1.00 | ALDH1A1 (0.93) | — | |
| Methyl Isobutyl Ketone SCHEMBL27468808 | 0.97 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL1580340 | 0.97 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL1128055 | 0.97 | ALDH1A1 (1.00) | — | |
| Methyl Isobutyl Ketone SCHEMBL15458 | 0.97 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL8421472 | 0.93 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL842835 | 0.93 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL2188913 | 0.93 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL809423 | 0.93 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL31261525 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116698801-A | Heavy metal content detection method | 广检检测技术(武汉)有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-117986229-A | Sulfonium salt, resist material and pattern forming method | 信越化学工业株式会社 | 2024-05-07 | — | — | CN | disclosed |
| CN-116698801-A | Heavy metal content detection method | 广检检测技术(武汉)有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115595495-A | Fe-Hf-rare earth intermediate alloy and preparation method thereof | 南通晶朋新材料科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115595495-A | Fe-Hf-rare earth intermediate alloy and preparation method thereof | 南通晶朋新材料科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-104292729-A | SEBS/PP (styrene-ethylene-butadiene-styrene/polypropylene) alloy melt-grafted maleic anhydride graft copolymer and preparation method thereof | NINGBO NENGZHIGUANG NEW MATERIALS TECHNOLOGY CO LTD | 2015-01-21 | — | — | CN | disclosed |
| CN-102382265-B | Polybasic grafted polyethylene and preparation method thereof | POLYMER SCI SHENZHEN NEW MAT | 2013-06-05 | — | — | CN | disclosed |
| CN-102391437-B | Multi-grafted acrylonitrile-butadiene-styrene (ABS) copolymer and preparation method thereof | POLYMER SCI SHENZHEN NEW MAT | 2013-04-24 | — | — | CN | disclosed |
| CN-102311606-B | Low-odour SEBS (styrene butadiene styrene block copolymer) melt-grafting maleic anhydride and preparation method thereof | POLYMER SCI SHENZHEN NEW MAT | 2013-03-20 | — | — | CN | disclosed |
| CN-102321327-B | Multi-grafted phenylethylene-ethylene-butylene copolymer and preparation method thereof | POLYMER SCI SHENZHEN NEW MAT | 2013-02-27 | — | — | CN | disclosed |
| CN-102030866-A | Polybasic grafted ethylene propylene diene monomer rubber and preparation method thereof | POLYMER SCI SHENZHEN NEW MAT | 2011-04-27 | — | — | CN | disclosed |
| CN-101880432-A | Polyhydric graft ethylene-octene copolymer and preparation method thereof | POLYMER SCI SHENZHEN NEW MAT | 2010-11-10 | — | — | CN | disclosed |
| CN-101573339-A | Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and processes for their preparation | GLENMARK PHARMACEUTICALS SA (CH) | 2009-11-04 | — | — | CN | disclosed |
| EP-0439096-B1 | Improvements in or relating to beta lactam production | BIOCHEMIE GMBH (AT) | 2003-12-17 | — | — | EP | disclosed |
| EP-1248787-A2 | NOVEL SUBTITUTED PYRAZOLO[4, 3-E]DIAZEPINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, USE AS MEDICINAL PRODUCTS AND PROCESSES FOR PREPARING THEM | WARNER-LAMBERT COMPANY (US) | 2002-10-16 | — | — | EP | disclosed |
| WO-2001049689-A2 | NOVEL SUBSTITUTED PYRAZOLO[4,3-e]DIAZEPINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, USE AS MEDICINAL PRODUCTS AND PROCESSES FOR PREPARING THEM | WARNER-LAMBERT COMPANY (US) | 2001-07-12 | — | — | WO | disclosed |
| EP-0976755-A1 | Improvements in or relating to beta lactam production | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2000-02-02 | — | — | EP | disclosed |
| US-5840885-A | REACTING WITH A MIXED CARBOXYLIC ANHYDRIDE IN A HALOGEN-FREE SOLVENT | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1998-11-24 | — | — | US | disclosed |
| US-5719276-A | — | — | 1998-02-17 | — | — | US | disclosed |
| EP-0439096-A2 | Improvements in or relating to beta lactam production | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1991-07-31 | — | — | EP | disclosed |