Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28449243 | 0.98 | CYP3A4 (0.34) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| Benzidine SCHEMBL28067578 | 0.98 | CYP3A4 (0.39) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| Hydrochloric Acid SCHEMBL18986246 | 0.98 | CYP3A4 (0.34) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| SCHEMBL844893 | 0.98 | CYP3A4 (0.37) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| SCHEMBL28757121 | 0.96 | CYP3A4 (0.36) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| Methane SCHEMBL27873846 | 0.96 | CYP3A4 (0.36) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| 1,4-Dichlorobenzene SCHEMBL3910732 | 0.91 | MAOB (0.36) | CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL5846158 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3286109 | 0.79 | CYP3A4 (0.37) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| Hydrochloric Acid SCHEMBL71899 | 0.79 | CYP3A4 (0.37) | CYP3A4TDP1ALDH1A1TP53TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-213698922-U | 3, 3-dichlorobenzidine hydrochloride centrifugal mother liquor solid-liquid separation device | 辽宁兰得新材料科技发展有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-210646205-U | 3, 3-dichlorobenzidine hydrochloride preparation mixing arrangement | 山东隆盛和助剂有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-210646307-U | 3, 3-dichlorobenzidine hydrochloride preparation catalyst adds device | 山东隆盛和助剂有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-210645308-U | 3, 3-dichlorobenzidine hydrochloride preparation filter equipment | 山东隆盛和助剂有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-210645205-U | 3, 3-dichlorobenzidine hydrochloride preparation crystallization device | 山东隆盛和助剂有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-109627803-B | Production method of environment-friendly organic pigment benzidine yellow G | 山东世纪阳光科技有限公司 | 2020-05-19 | — | — | CN | claimed |
| CN-210512393-U | 3, 3-dichlorobenzidine hydrochloride preparation drying device | 山东隆盛和助剂有限公司 | 2020-05-12 | — | — | CN | claimed |
| CN-109627803-A | The production method of environment-friendly type organic pigment benzidine yellow G | 山东世纪阳光科技有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-1752032-A | Treatment and recovery technology for mixed acid from industrial waste water 3,3-dichlorobenzidine hydrochloride | XIA NIANRAN (CN) | 2006-03-29 | — | — | CN | claimed |
| CN-115945157-A | Device and process for continuously preparing 3, 3-dichlorobenzidine diazonium salt | 沈阳化工研究院有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-218529988-U | 3,3' -dichlorobenzidine hydrochloride centrifugal material recovery device | 辽宁兰得新材料科技发展有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-217549047-U | Dichlorobenzidine salt cooling crystallization equipment | 辽宁兰得新材料科技发展有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-217418435-U | Waste acid treatment and recovery device for 3, 3-dichlorobenzidine production | 辽宁兰得新材料科技发展有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-217418436-U | DCB reduction wastewater recycling device | 辽宁兰得新材料科技发展有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-1752032-A | Treatment and recovery technology for mixed acid from industrial waste water 3,3-dichlorobenzidine hydrochloride | XIA NIANRAN (CN) | 2006-03-29 | — | — | CN | disclosed |
| CN-1752032-A | Treatment and recovery technology for mixed acid from industrial waste water 3,3-dichlorobenzidine hydrochloride | XIA NIANRAN (CN) | 2006-03-29 | — | — | CN | disclosed |
| EP-0952191-B1 | Disazo pigment composition, printing ink containing the same and a method for manufacturing the same | DAINIPPON INK & CHEMICALS (JP) | 2002-07-10 | — | — | EP | disclosed |
| EP-0952191-A2 | Disazo pigment composition, printing ink containing the same and a method for manufacturing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-5958128-A | CONTINUOUSLY FEEDING AN ACETOACETANILIDE DERIVATIVE AS A COUPLER AND A TETRAAZO BENZIDINE DERIVATIVE INTO AN ACIDIC AQUEOUS SOLUTION TO FORM DISAZO PIGMENT | TOYO INK MANUFACTURING CO., LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0826742-A1 | PROCESS FOR THE PREPARATION OF DISAZO PIGMENTS AND DISAZO PIGMENTS PREPARED BY THE PROCESS | TOYO INK MANUFACTURING CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |