Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11274151 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL27840163 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL28475208 | 0.95 | TSHR (0.46) | — | |
| SCHEMBL27338397 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL9308564 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL28732041 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL11598288 | 0.90 | — | — | |
| SCHEMBL6323 | 0.89 | — | — | |
| SCHEMBL891350 | 0.89 | TSHR (0.50) | — | |
| SCHEMBL8157971 | 0.89 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191265-A1 | METHODS FOR TREATING PULMONARY FIBROSIS | DAVID WEINSTEIN CONSULTING, INC. (US) | 2020-09-24 | — | — | WO | disclosed |
| US-10709686-B2 | Methods for treating pulmonary fibrosis | DAVID WEINSTEIN CONSULTING, INC. (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190290612-A1 | METHODS FOR TREATING PULMONARY FIBROSIS | DAVID WEINSTEIN CONSULTING INC (US) | 2019-09-26 | — | — | US | disclosed |
| EP-3432987-A1 | METHODS FOR WOUND HEALING AND SCAR PREVENTION | Weinstein, David (US) | 2019-01-30 | — | — | EP | disclosed |
| US-20180140576-A1 | METHODS FOR WOUND HEALING AND SCAR PREVENTION | DAVID WEINSTEIN CONSULTING INC (US) | 2018-05-24 | — | — | US | disclosed |
| WO-2017165119-A1 | METHODS FOR WOUND HEALING AND SCAR PREVENTION | WEINSTEIN DAVID (US) | 2017-09-28 | — | — | WO | disclosed |
| US-20170266157-A1 | METHODS FOR WOUND HEALING AND SCAR PREVENTION | DAVID WEINSTEIN CONSULTING, INC. | 2017-09-21 | — | — | US | disclosed |
| US-6387881-B1 | PEPTIDE | TRIGEN LTD (GB) | 2002-05-14 | — | — | US | disclosed |
| EP-0509080-B1 | INHIBITORS AND SUBSTRATES OF THROMBIN | TRIGEN LTD (GB) | 2000-08-16 | — | — | EP | disclosed |
| EP-0955309-A1 | Inhibitors and substrates of thrombin | TRIGEN LIMITED (GB) | 1999-11-10 | — | — | EP | disclosed |
| US-5858979-A | ANTICOAGULANT PEPTIDES | TRIGEN LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| EP-0807638-A1 | Inhibitors and substrates of thrombin | THROMBOSIS RESEARCH INSTITUTE (GB) | 1997-11-19 | — | — | EP | disclosed |
| US-5648338-A | PEPTIDE ANTICOAGULANT | THROMBOSIS RESEARCH INSTITUTE (GB) | 1997-07-15 | — | — | US | disclosed |
| EP-0509080-A1 | INHIBITORS AND SUBSTRATES OF THROMBIN | ELLERMAN PHARMACEUTICALS LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |
| WO-1992007869-A1 | INHIBITORS AND SUBSTRATES OF THROMBIN | THROMBOSIS RESEARCH INSTITUTE (GB) | 1992-05-14 | — | — | WO | disclosed |