Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27840163 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL28475208 | 0.95 | TSHR (0.46) | — | |
| Ammonia Solution, Strong SCHEMBL4222522 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL11274151 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL24170 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL11598288 | 0.90 | — | — | |
| Bromide SCHEMBL27822398 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL7716992 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL28732041 | 0.90 | — | — | |
| SCHEMBL8157971 | 0.89 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332434-B2 | Synthesis of levomethadone hydrochloride | SAFAEI GHOMI JAVAD (IR) | 2022-05-17 | — | — | US | claimed |
| WO-2020212890-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE | SAFAEI GHOMI JAVAD (IR) | 2020-10-22 | — | — | WO | claimed |
| US-20200277250-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE | SAFAEI GHOMI JAVAD (IR) | 2020-09-03 | — | — | US | claimed |
| CN-118119609-A | Imidazole derivatives and their use as antibiotics | 豪夫迈·罗氏有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-118044519-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117715892-A | Quaternary ammonium cation substituted compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117677628-A | GHR binding pending peptides and compositions comprising the same | 肽梦想株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-110072842-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-113906024-B | Condensed heterocyclic compound having nitrogen atom in crosslinking part, salt thereof, agricultural and horticultural insecticide containing the same, and method for using the same | 日本农药株式会社 | 2023-10-20 | — | — | CN | disclosed |
| CN-116462635-A | Pyrazine-1 (2H) -2-oxo compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-115968290-A | Oxazolidinones, liposomal compositions comprising oxazolidinones, and methods of using the same | 阿卡格拉医药公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-1415596-A | Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science | INST OF TOXICANT AND MEDICAMEN (CN) | 2003-05-07 | — | — | CN | disclosed |
| CN-1365967-A | Amine derivative with K channel regulation function and its preparing process and application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2002-08-28 | — | — | CN | disclosed |
| CN-1365966-A | Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2002-08-28 | — | — | CN | disclosed |
| US-5284976-A | Method of producing primary amines in high yields | ALDRICH CHEMICAL COMPANY, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5276195-A | Process for producing dimethylorganoboranes | ALDRICH CHEMICAL COMPANY, INC. (US) | 1994-01-04 | — | — | US | disclosed |
| US-5214209-A | Method of producing primary amines in high yields and novel intermediates therefor | ALDRICH CHEMICAL COMPANY, INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5210310-A | Optically active dimethylorganoboranes | ALDRICH CHEMICAL CO., INC. (US) | 1993-05-11 | — | — | US | disclosed |
| US-5087700-A | Method of producing primary amines in high yields | ALDRICH CHEMICAL COMPANY, INC. (US) | 1992-02-11 | — | — | US | disclosed |
| US-4918229-A | Method of producing primary amines in high yields and novel intermediates therefor | ALDRICH CHEMICAL COMPANY, INC. (US) | 1990-04-17 | — | — | US | disclosed |