Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.32 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRNA7 known ✓ | P36544 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8526282 | 0.97 | BBOX1 (0.40) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Hydrochloric Acid SCHEMBL4587004 | 0.97 | BBOX1 (0.43) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Hydrochloric Acid SCHEMBL7744315 | 0.97 | BBOX1 (0.43) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Hydrochloric Acid SCHEMBL4587394 | 0.97 | BBOX1 (0.43) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Hydrochloric Acid SCHEMBL425619 | 0.97 | BBOX1 (0.43) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Ammonia Solution, Strong SCHEMBL2368198 | 0.97 | BBOX1 (0.43) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Hydrochloric Acid SCHEMBL28603921 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Hydrochloric Acid SCHEMBL7744310 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Hydrochloric Acid SCHEMBL10511528 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Hydrochloric Acid SCHEMBL11492828 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1TSHRKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407977-A | A kind of ionic copolymer preparation and its method for self-assembled modified microporous polypropylene membrane | UNIV CHANGZHOU | 2019-11-05 | — | — | CN | claimed |
| CN-109465033-A | A kind of preparation method for the carbon nano tube air purifier removing formaldehyde | 梅玉杰 | 2019-03-15 | — | — | CN | claimed |
| CN-117480237-A | Fabric spray composition | 联合利华知识产权控股有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2023098719-A1 | METHOD FOR PREPARING CERIUM OXIDE NANOCOMPOSITE, CERIUM OXIDE NANOCOMPOSITE, AND CHEMICAL MECHANICAL POLISHING SOLUTION | 安集微电子（上海）有限公司 | 2023-06-08 | — | — | WO | disclosed |
| CN-114380373-A | Composite coagulant, preparation method thereof and application thereof in treatment of secondary effluent of sewage plant | 天津大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-111225971-A | Improvements in and relating to refreshing of laundry | 荷兰联合利华有限公司 | 2020-06-02 | — | — | CN | disclosed |
| CN-111212897-A | Improvements in and relating to refreshing of laundry | 荷兰联合利华有限公司 | 2020-05-29 | — | — | CN | disclosed |
| CN-111212895-A | Aqueous spray composition | 荷兰联合利华有限公司 | 2020-05-29 | — | — | CN | disclosed |
| CN-107434943-B | A kind of preparation method of fire resistant coating | 广州和新实业有限公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-110290776-A | METHOD FOR IMPROVING STORAGE STABILITY OF COSMETIC | 株式会社ADEKA | 2019-09-27 | — | — | CN | disclosed |
| CN-107334194-B | A kind of anti-dust mask | 梅玉杰 | 2019-03-15 | — | — | CN | disclosed |
| CN-104837880-B | Vinyl alcohol graft polymer, method for producing same, and ion-exchange membrane using same | 可乐丽股份有限公司 | 2017-09-15 | — | — | CN | disclosed |
| CN-103269727-B | Water-based air freshener compositions, systems, and methods of use thereof | 阿吉莱克斯香料和香水公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-103648468-B | Use of microemulsions in cosmetic cleaning compositions | 考格尼斯知识产权管理有限责任公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-101244017-B | Method for permanently deforming keratinous fibres including a step of applying a reducing composition with a low concentration and an intermediate drying step | OREAL | 2012-03-21 | — | — | CN | disclosed |
| CN-100497800-C | Process for treating a lipophilic fluid | PROCTER & GAMBLE (US) | 2009-06-10 | — | — | CN | disclosed |
| CN-1612960-A | Process for treating a lipophilic fluid | PROCTER & GAMBLE (US) | 2005-05-04 | — | — | CN | disclosed |
| CN-1599642-A | Filter for removing water and/or surfactants from lipophilic fluids | PROCTER & GAMBLE (US) | 2005-03-23 | — | — | CN | disclosed |
| CN-1553823-A | Consumable container comprising a filter | — | 2004-12-08 | — | — | CN | disclosed |
| US-5853542-A | Method of sizing paper using a sizing agent and a polymeric enhancer and paper produced thereof | HERCULES INCORPORATED (US) | 1998-12-29 | — | — | US | disclosed |