Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dipicolinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.94 |
| ▸ | TSHR | P16473 | 2/20 | 0.94 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.94 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipicolinic Acid SCHEMBL890374 | 1.00 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL321128 | 1.00 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL720696 | 0.97 | KDM4E (1.00) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL34595 | 0.97 | KDM4E (1.00) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL6561776 | 0.94 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL3732330 | 0.94 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL11294102 | 0.94 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL6556692 | 0.94 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL9659122 | 0.94 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL15659942 | 0.94 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659643-B | Polyester material resistant to wet heat aging and preparation method thereof | 扬州君禾薄膜科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117843914-B | Preparation method of high-performance self-repairing elastomer material for self-repairing inner tube or other elastic materials | 内蒙古科技大学 | 2024-05-14 | — | — | CN | claimed |
| CN-117624789-B | Modified polypropylene composite pipe and preparation process thereof | 杭州佳磊环保科技有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117843914-A | Preparation method of high-performance self-repairing elastomer material for self-repairing inner tube or other elastic materials | 内蒙古科技大学 | 2024-04-09 | — | — | CN | claimed |
| CN-117659643-A | Polyester material resistant to wet heat aging and preparation method thereof | 扬州君禾薄膜科技有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117624789-A | Modified polypropylene composite pipe and preparation process thereof | 杭州佳磊环保科技有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117362628-A | Perfluoro polyether type conductive agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-114478584-B | Cu based on rhodamine B 2+ Fluorescent sensor and preparation method thereof | 南京理工大学 | 2023-09-26 | — | — | CN | claimed |
| CN-115925725-A | Aluminum ion fluorescent probe, preparation method and application | 杭州珈晟生物数字技术有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115746025-A | Cycloocta-tetrathiophene macrocyclic molecule and preparation method and application thereof | 河南大学 | 2023-03-07 | — | — | CN | claimed |
| CN-115010667-A | Temperature-resistant and salt-resistant polymer surfactant for oil displacement and preparation method thereof | 山东科兴化工有限责任公司 | 2022-09-06 | — | — | CN | claimed |
| CN-111518279-B | Polysiloxane based on aromatic disulfide bond and application thereof | 南京大学 | 2021-09-28 | — | — | CN | claimed |
| CN-109651601-B | Novel hydrogen bond crosslinking stretchable conductive polymer and synthesis method thereof | 江西科技师范大学 | 2021-06-04 | — | — | CN | claimed |
| CN-109422880-B | Preparation method of self-repairing silicon elastomer hybridized and crosslinked by metal coordination bond and hydrogen bond and elastomer | 北京化工大学 | 2020-06-26 | — | — | CN | claimed |
| CN-111072557-A | Amide type Gemini surfactant and preparation method thereof | 江南大学 | 2020-04-28 | — | — | CN | claimed |
| WO-2003082824-A1 | SYNTHESIS OF 2,6-DICARBONYLPYRIDINES | BOULDER SCIENTIFIC COMPANY (US) | 2003-10-09 | — | — | WO | claimed |
| US-20030187271-A1 | Synthesis of 2, 6-dicarbonylpyridines | BOULDER SCIENTIFIC COMPANY | 2003-10-02 | — | — | US | claimed |
| JP-9176120-A | — | — | None | — | — | JP | disclosed |
| US-3954868-A | Bis(diphenylaminomethane) antimicrobial agents | UNIROYAL, INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3931142-A | Heterocyclic containing disazo compounds | CIBA-GEIGY AG (CH) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187271-A1 | Synthesis of 2, 6-dicarbonylpyridines | DDT, DHPS, PAH | CA2 690/4885KDM4E 1372/4885ALOX15 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.