Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7999679 | 0.98 | ZDHHC20 (0.39) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL5682118 | 0.98 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL28195094 | 0.83 | TSHR (0.39) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL28053903 | 0.81 | — | — | |
| SCHEMBL3319884 | 0.79 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL21143016 | 0.77 | TSHR (0.41) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL28164352 | 0.73 | — | — | |
| SCHEMBL20543334 | 0.72 | ZDHHC20 (0.48) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL27636945 | 0.72 | TSHR (0.41) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL471967 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995302-B2 | Liquid acidic hard surface cleaning compositions having improved viscosity | THE PROCTER & GAMBLE COMPANY (US) | 2021-05-04 | — | — | US | claimed |
| EP-3569683-B1 | LIQUID ACIDIC HARD SURFACE CLEANING COMPOSITIONS PROVIDING IMPROVED MAINTENANCE OF SURFACE SHINE, AND PREVENTION OF WATER MARKS AND SPLASH MARKS | PROCTER & GAMBLE (US) | 2020-10-14 | — | — | EP | claimed |
| US-20190352584-A1 | LIQUID ACIDIC HARD SURFACE CLEANING COMPOSITIONS PROVIDING IMPROVED MAINTENANCE OF SURFACE SHINE, AND PREVENTION OF WATER MARKS AND SPLASH MARKS | THE PROCTER & GAMBLE COMPANY | 2019-11-21 | — | — | US | claimed |
| US-20190352579-A1 | LIQUID ACIDIC HARD SURFACE CLEANING COMPOSITIONS HAVING IMPROVED VISCOSITY | THE PROCTER & GAMBLE COMPANY | 2019-11-21 | — | — | US | claimed |
| EP-3569682-A1 | LIQUID HARD SURFACE CLEANING COMPOSITIONS HAVING IMPROVED VISCOSITY | The Procter & Gamble Company (US) | 2019-11-20 | — | — | EP | claimed |
| EP-3569683-A1 | LIQUID ACIDIC HARD SURFACE CLEANING COMPOSITIONS PROVIDING IMPROVED MAINTENANCE OF SURFACE SHINE, AND PREVENTION OF WATER MARKS AND SPLASH MARKS | The Procter & Gamble Company (US) | 2019-11-20 | — | — | EP | claimed |
| CN-101686902-B | Personal care compositions comprising at least two cationic polymers and an anionic surfactant | PROCTER & GAMBLE | 2013-08-21 | — | — | CN | claimed |
| CN-101686902-A | Personal care compositions comprising at least two cationic polymers and an anionic surfactant | PROCTER & GAMBLE | 2010-03-31 | — | — | CN | claimed |
| EP-0580529-B1 | Process for making paper or cardboard having improved retention | S N F (FR) | 1996-04-17 | — | — | EP | claimed |
| US-10995302-B2 | Liquid acidic hard surface cleaning compositions having improved viscosity | THE PROCTER & GAMBLE COMPANY (US) | 2021-05-04 | — | — | US | disclosed |
| US-10920180-B2 | Liquid acidic hard surface cleaning compositions providing improved maintenance of surface shine, and prevention of water marks and splash marks | THE PROCTER & GAMBLE COMPANY (US) | 2021-02-16 | — | — | US | disclosed |
| EP-3569683-B1 | LIQUID ACIDIC HARD SURFACE CLEANING COMPOSITIONS PROVIDING IMPROVED MAINTENANCE OF SURFACE SHINE, AND PREVENTION OF WATER MARKS AND SPLASH MARKS | PROCTER & GAMBLE (US) | 2020-10-14 | — | — | EP | disclosed |
| US-20190352579-A1 | LIQUID ACIDIC HARD SURFACE CLEANING COMPOSITIONS HAVING IMPROVED VISCOSITY | THE PROCTER & GAMBLE COMPANY | 2019-11-21 | — | — | US | disclosed |
| US-20190352584-A1 | LIQUID ACIDIC HARD SURFACE CLEANING COMPOSITIONS PROVIDING IMPROVED MAINTENANCE OF SURFACE SHINE, AND PREVENTION OF WATER MARKS AND SPLASH MARKS | THE PROCTER & GAMBLE COMPANY | 2019-11-21 | — | — | US | disclosed |
| CN-101686902-B | Personal care compositions comprising at least two cationic polymers and an anionic surfactant | PROCTER & GAMBLE | 2013-08-21 | — | — | CN | disclosed |
| CN-101712730-B | Preparation method of water-soluble polymer dispersion | BEIJING RESPONSE CHEMICAL CO LTD | 2011-07-27 | — | — | CN | disclosed |
| CN-101712730-A | Preparation method of water-soluble polymer dispersion | BEIJING RESPONSE CHEMICAL CO L | 2010-05-26 | — | — | CN | disclosed |
| CN-101686902-A | Personal care compositions comprising at least two cationic polymers and an anionic surfactant | PROCTER & GAMBLE | 2010-03-31 | — | — | CN | disclosed |
| EP-0809482-A1 | AGENT CONTAINING CORROSIVE COMPONENTS AND DISPENSER | Henkel Kommanditgesellschaft auf Aktien (DE) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025138-A1 | AGENT CONTAINING CORROSIVE COMPONENTS AND DISPENSER | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1996-08-22 | — | — | WO | disclosed |