Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 7/20 | 0.52 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 5/20 | 0.52 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.52 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.52 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | CES2 | O00748 | 4/20 | 0.54 |
| ▸ | CES1 | P23141 | 4/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30741334 | 1.00 | ALDH1A1 (0.77) | ALDH1A1CES2CES1GPR84PPARG | |
| Hydrochloric Acid SCHEMBL4886991 | 1.00 | ALDH1A1 (0.77) | ALDH1A1CES2CES1GPR84PPARG | |
| Hydrochloric Acid SCHEMBL27424696 | 0.98 | ALDH1A1 (0.74) | ALDH1A1CES2CES1GPR84PPARG | |
| SCHEMBL3098865 | 0.98 | ALDH1A1 (0.81) | ALDH1A1CES2CES1GPR84PPARG | |
| SCHEMBL9688302 | 0.98 | ALDH1A1 (0.81) | ALDH1A1CES2CES1GPR84PPARG | |
| SCHEMBL740728 | 0.98 | ALDH1A1 (0.81) | ALDH1A1CES2CES1GPR84PPARG | |
| Hexadecanoic Acid Dimethylamide SCHEMBL148603 | 0.98 | ALDH1A1 (0.81) | ALDH1A1CES2CES1GPR84PPARG | |
| SCHEMBL22406917 | 0.98 | ALDH1A1 (0.81) | ALDH1A1CES2CES1GPR84PPARG | |
| SCHEMBL160049 | 0.98 | ALDH1A1 (0.81) | ALDH1A1CES2CES1GPR84PPARG | |
| SCHEMBL17061008 | 0.98 | ALDH1A1 (0.81) | ALDH1A1CES2CES1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116456953-A | Water-in-oil type emulsified cosmetic | 株式会社资生堂 | 2023-07-18 | — | — | CN | disclosed |
| CN-108862527-B | Floating flocculation composition for green algae and method for removing green algae using same | 顺天大学校产学协力团 | 2021-09-14 | — | — | CN | disclosed |
| CN-102802601-B | Tyr-Arg dipeptides is preventing the cosmetic applications of skin sagging | 赛德玛公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-102596154-B | Dentifrice comprising stannous fluoride plus zinc citrate and low levels of water | COLGATE PALMOLIVE CO | 2014-12-24 | — | — | CN | disclosed |
| CN-101854907-B | Cosmetic composition comprising hydroxymethionine and 3-aminopropanesulfonic acid | SEDERMA SA | 2014-06-18 | — | — | CN | disclosed |
| CN-102802601-A | Cosmetic use of tyr-arg dipeptide to combat cutaneous sagging | SEDERMA SA | 2012-11-28 | — | — | CN | disclosed |
| CN-102596154-A | Dentifrice comprising stannous fluoride plus zinc citrate and low levels of water | COLGATE PALMOLIVE CO | 2012-07-18 | — | — | CN | disclosed |
| CN-1977792-B | Cosmetic composition comprising a cation, a liquid fatty substance and a sorbitan ester, and cosmetic treatment process | OREAL | 2012-03-21 | — | — | CN | disclosed |
| CN-1893911-B | Formula including tetrapeptide and tripeptide mixture | SEDERMA SA | 2010-12-29 | — | — | CN | disclosed |
| CN-101854907-A | Cosmetic composition comprising hydroxymethionine and 3-aminopropanesulfonic acid | SEDERMA SA | 2010-10-06 | — | — | CN | disclosed |
| CN-100574862-C | The material that capsule is sealed | INT FLAVORS & FRAGRANCES INC | 2009-12-30 | — | — | CN | disclosed |
| CN-101460053-A | Methods and articles having a high antiviral and antibacterial efficacy | DIAL CORP (US) | 2009-06-17 | — | — | CN | disclosed |
| CN-101454012-A | Method for increased control of viruses on skin | THR DIAL CORP (US) | 2009-06-10 | — | — | CN | disclosed |
| CN-1977792-A | Cosmetic composition comprising a cation, a liquid fatty substance and a sorbitan ester, and cosmetic treatment process | OREAL (FR) | 2007-06-13 | — | — | CN | disclosed |
| CN-1893911-A | Formula including tetrapeptide and tripeptide mixture | SEDERMA SA (FR) | 2007-01-10 | — | — | CN | disclosed |
| CN-1208020-C | Biocide impregnated fibre reinforced sponge material | KALLE NALO GMBH (DE) | 2005-06-29 | — | — | CN | disclosed |
| CN-1233164-A | Biocide impregnated fibre reinforced sponge material | KALLE NALO GMBH (DE) | 1999-10-27 | — | — | CN | disclosed |
| CN-1227740-A | Stratum corneum care method | KAO CORP (JP) | 1999-09-08 | — | — | CN | disclosed |
| EP-0538762-B1 | Hair cosmetic | KAO CORP (JP) | 1996-04-10 | — | — | EP | disclosed |
| EP-0538762-A1 | Hair cosmetic | KAO CORPORATION (JP) | 1993-04-28 | — | — | EP | disclosed |