SCHEMBL9100742

SCHEMBL9100742

CCCNc1nc(NCCC)nc(N(C)OCC(C)C)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
GAA P10253 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KMT2A Q03164 3/20 0.36
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 3/20 0.35
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
HTR7 P34969 1/20 0.34
ALDH1A1 P00352 4/20 0.33
TSHR P16473 1/20 0.33
CREBBP Q92793 1/20 0.33
PKM P14618 1/20 0.33
RAD52 P43351 1/20 0.33
NR1I2 O75469 1/20 0.33
AHR P35869 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL9108745 0.92 CA1 (0.39) CYP1A2CYP2C19GAAL3MBTL1KMT2A
Sulfuric Acid SCHEMBL9108754 0.89 CA1 (0.40) CYP1A2CYP2C19GAAL3MBTL1KMT2A
SCHEMBL9106534 0.83 CYP1A2 (0.46) CYP1A2CYP2C19GAAL3MBTL1KMT2A
SCHEMBL9102460 0.81 CYP1A2 (0.44) CYP1A2CYP2C19GAAL3MBTL1KMT2A
Ena-001 SCHEMBL9105353 0.78 CYP1A2 (0.51) CYP1A2CYP2C19GAAL3MBTL1KMT2A
SCHEMBL15720201 0.77 CYP1A2 (0.41) CYP1A2CYP2C19GAAL3MBTL1KMT2A
SCHEMBL9102468 0.76 CYP1A2 (0.40) CYP1A2CYP2C19GAAL3MBTL1KMT2A
SCHEMBL17169332 0.76 HTT (0.46) CYP1A2CYP2C19GAAL3MBTL1KMT2A
Sulfuric Acid SCHEMBL9108715 0.76 CA1 (0.43) CYP1A2CYP2C19GAAL3MBTL1KMT2A
Hydrochloric Acid SCHEMBL15720288 0.76 CYP1A2 (0.40) CYP1A2CYP2C19GAAL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160256463-A1 NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS INC (US) 2016-09-08 US claimed
US-9351972-B2 Compounds as respiratory stimulants for treatment of breathing control disorders or diseases GALLEON PHARMACEUTICALS, INC. (US) 2016-05-31 US claimed
US-20150374706-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. 2015-12-31 US claimed
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. 2014-12-18 US claimed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US claimed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US claimed
US-20260137675-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT DRUG OVERDOSE ENALARE THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-12544369-B2 Methods and pharmaceutical compositions to treat drug overdose ENALARE THERAPEUTICS INC. (US) 2026-02-10 US disclosed
US-20250325554-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT RESPIRATORY DEPRESSION IN PATIENTS ENALARE THERAPEUTICS INC (US) 2025-10-23 US disclosed
EP-4543455-A2 METHODS OF TREATING NEUROLOGICAL VENTILATORY INSUFFICIENCY Enalare Therapeutics Inc. (US) 2025-04-30 EP disclosed
WO-2025080559-A1 METHODS AND COMPOSITIONS FOR TREATING DRUG OVERDOSE ENALARE THERAPEUTICS INC. (US) 2025-04-17 WO disclosed
US-20250114370-A1 METHODS AND COMPOSITIONS FOR TREATING DRUG OVERDOSE ENALARE THERAPEUTICS INC (US) 2025-04-10 US disclosed
EP-4504206-A2 RESPIRATORY STIMULANT NASAL FORMULATIONS Enalare Therapeutics Inc. (US) 2025-02-12 EP disclosed
WO-2013181217-A2 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. (US) 2013-12-05 WO disclosed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US disclosed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US disclosed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544369-B2 Methods and pharmaceutical compositions to treat drug overdose OPRK1, OPRD1, OPRM1 CYP1A2 138/4885CYP2C19 308/4885GAA 1777/4885
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases MTNR1B, CHRM3, ADRA2C CYP1A2 457/4885CYP2C19 672/4885GAA 342/4885
US-20260137675-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT DRUG OVERDOSE ADRA2B, ADRB1, ADRB2 CYP1A2 89/4885CYP2C19 93/4885GAA 1929/4885
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases PER2, SMPD4, NDUFB5 CYP1A2 1058/4885CYP2C19 1600/4885GAA 563/4885
US-20250325554-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT RESPIRATORY DEPRESSION IN PATIENTS NDUFB6, NDUFB7, CHRM5 CYP1A2 895/4885CYP2C19 801/4885GAA 804/4885
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES PER2, MTNR1B, NDUFB5 CYP1A2 2352/4885CYP2C19 3493/4885GAA 530/4885
US-20160256463-A1 NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES P2RX5, HRH2, ADRA2C CYP1A2 472/4885CYP2C19 677/4885GAA 672/4885
US-20250114370-A1 METHODS AND COMPOSITIONS FOR TREATING DRUG OVERDOSE ADRA2A, ADRA2C, OPRM1 CYP1A2 50/4885CYP2C19 288/4885GAA 434/4885
US-20150374706-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES PER2, SMPD4, NDUFB5 CYP1A2 1058/4885CYP2C19 1600/4885GAA 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.