Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 8/20 | 0.56 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.53 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 3/20 | 0.49 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.47 |
| ▸ | SCN8A known ✓ | Q9UQD0 | 1/20 | 0.47 |
| ▸ | CHRM4 known ✓ | P08173 | 4/20 | 0.45 |
| ▸ | CHRM5 known ✓ | P08912 | 4/20 | 0.45 |
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.45 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.45 |
| ▸ | BCHE known ✓ | P06276 | 1/20 | 0.45 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144038 | 0.98 | CHRM2 (0.58) | CHRM2MEN1KMT2ATDP1MAOA | |
| Hydrochloric Acid SCHEMBL9759994 | 0.97 | CHRM2 (0.61) | CHRM2MEN1KMT2ATDP1MAOA | |
| Hydrochloric Acid SCHEMBL9760502 | 0.95 | CHRM2 (0.64) | CHRM2MEN1KMT2ATDP1MAOA | |
| Hydrochloric Acid SCHEMBL9760971 | 0.95 | CHRM2 (0.64) | CHRM2MEN1KMT2ATDP1MAOA | |
| SCHEMBL48855 | 0.95 | MAOA (0.58) | CHRM2MEN1KMT2ATDP1MAOA | |
| SCHEMBL25335334 | 0.94 | MAOA (0.56) | CHRM2MEN1KMT2ATDP1MAOA | |
| Hydrochloric Acid SCHEMBL9760794 | 0.92 | CHRM2 (0.64) | CHRM2MEN1KMT2ATDP1MAOA | |
| Methylamine SCHEMBL3624091 | 0.92 | MAOA (0.55) | CHRM2MEN1KMT2ATDP1MAOA | |
| Hydrochloric Acid SCHEMBL28373204 | 0.90 | MEN1 (0.57) | CHRM2MEN1KMT2ATDP1MAOA | |
| SCHEMBL15360358 | 0.90 | MAOA (0.61) | CHRM2MEN1KMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271953-A | Modified polyurethane primer and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118146520-A | Rubber powder polymer grafted block copolymer composite modified asphalt, preparation method and regeneration application thereof | 山东交通学院 | 2024-06-07 | — | — | CN | claimed |
| CN-115637021-B | Epoxy resin composite material with modified silicon dioxide synergistically dispersed and preparation and application thereof | 华中科技大学 | 2024-05-14 | — | — | CN | claimed |
| US-20240124673-A1 | POLYMER BASED SENSORS FOR DETECTING AGRICULTURAL ANALYTES AND METHODS OF MAKING SAME | GEORGIA TECH RESEARCH CORPORATION | 2024-04-18 | — | — | US | claimed |
| US-11879045-B2 | Polymer based sensors for detecting agricultural analytes and methods of making same | GEORGIA TECH RESEARCH CORPORATION (US) | 2024-01-23 | — | — | US | claimed |
| CN-113774651-B | Surface modification method for liquid crystal polymer material | 上海普利特复合材料股份有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-115975279-A | Municipal water supply pipeline plastic and preparation method thereof | 江苏建宏管业科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115637021-A | Modified silicon dioxide synergistically dispersed epoxy resin composite material and preparation and application thereof | 华中科技大学 | 2023-01-24 | — | — | CN | claimed |
| CN-112534011-B | Aqueous, storage-stable compositions containing N-benzyl-substituted N- (2-aminoethyl) -3-aminopropylsiloxane hydrochloride, method for the production thereof and use thereof | 赢创运营有限公司 | 2022-04-26 | — | — | CN | claimed |
| US-11292911-B2 | Aqueous, storage-stable composition containing N-benzyl-substituted N-(2-aminoethyl)-3-aminopropylsiloxane hydrochlorides, processes for production thereof and use thereof | EVONIK OPERATIONS GMBH (DE) | 2022-04-05 | — | — | US | claimed |
| WO-2009096922-A1 | HIGH QUALITY POROUS INK-JET MEDIA | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2009-08-06 | — | — | WO | claimed |
| US-20080268185-A1 | Multi-layered porous ink-jet recording media | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2008-10-30 | — | — | US | claimed |
| EP-1666270-B1 | Ink-jet ink-receiver sheet | HEWLETT PACKARD DEVELOPMENT CO (US) | 2008-08-20 | — | — | EP | claimed |
| EP-1809483-B1 | INK-JET MEDIA WITH MULTIPLE POROUS MEDIA COATING LAYERS | HEWLETT PACKARD DEVELOPMENT CO (US) | 2008-07-09 | — | — | EP | claimed |
| EP-1809483-A1 | INK-JET MEDIA WITH MULTIPLE POROUS MEDIA COATING LAYERS | Hewlett-Packard Development Company, L.P. (US) | 2007-07-25 | — | — | EP | claimed |
| EP-1666270-A1 | Ink-jet ink-receiver sheet | Hewlett-Packard Development Company, L.P. (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2006044106-A1 | INK-JET MEDIA WITH MULTIPLE POROUS MEDIA COATING LAYERS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2006-04-27 | — | — | WO | claimed |
| US-20060083870-A1 | Ink-jet media coatings including expoxy-functionalized inorganic particulates and amine-functionalized inorganic particulates | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2006-04-20 | — | — | US | claimed |
| US-20060083871-A1 | Ink-jet media with multiple porous media coating layers | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2006-04-20 | — | — | US | claimed |
| US-5591818-A | CATIONIC AMINOSILANE POLYMERS, ADHESION PROMOTERS, SIZING FOR GLASS FIBERS AND REINFORCEMENT FILLERS | HULS AKTIENGESELLSCHAFT (DE) | 1997-01-07 | — | — | US | claimed |