SCHEMBL9207641

SCHEMBL9207641

CC(C)(C)c1n[nH]c(=O)[nH]1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.40
GLA P06280 1/20 0.38
TSHR P16473 1/20 0.37
DAO P14920 1/20 0.35
BTK Q06187 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16082067 0.72 GLA (0.34) GLATSHR
SCHEMBL21324849 0.70 L3MBTL1 (0.57) L3MBTL1DAO
SCHEMBL19403690 0.70 HPGD (0.36) GLATSHRDAOBTKHPGD
SCHEMBL18269679 0.69 MEN1 (0.43) GLATSHRDAO
SCHEMBL23225408 0.64 GLA (0.34) GLATSHR
SCHEMBL13233284 0.64 GLA (0.54) GLATSHR
SCHEMBL166882 0.63
SCHEMBL17189455 0.61 L3MBTL1 (0.52) L3MBTL1
SCHEMBL84555 0.60 PTGS1 (0.43) L3MBTL1
SCHEMBL814784 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239809-A1 THERAPEUTIC AGENTS FOR ENHANCING EPITHELIAL AND/OR ENDOTHELIAL BARRIER FUNCTION ARTUS THERAPEUTICS INC (US) 2024-07-18 US disclosed
US-20230193231-A1 ENGINEERED GENE-EDITING PROTEINS FACTOR BIOSCIENCE INC. 2023-06-22 US disclosed
US-20230111853-A1 COMPOUNDS MODULATING PROTEIN RECRUITMENT AND/OR DEGRADATION ORIONIS BIOSCIENCES, INC. 2023-04-13 US disclosed
US-20220169611-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer AMGEN INC (US) 2022-06-02 US disclosed
US-11053251-B2 GPR35 modulators PROMETHEUS BIOSCIENCES, INC. (US) 2021-07-06 US disclosed
US-20210179560-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer AMGEN INC (US) 2021-06-17 US disclosed
US-20210009505-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS FACTOR BIOSCIENCE INC. 2021-01-14 US disclosed
US-20200239476-A1 GPR35 MODULATORS PROMETHEUS BIOSCIENCES, INC. 2020-07-30 US disclosed
US-20190133976-A1 METABOLICALLY ROBUST ANALOGS OF CYP-EICOSANOIDS FOR THE TREATMENT OF CARDIAC DISEASE OMEICOS THERAPEUTICS GMBH (DE) 2019-05-09 US disclosed
US-10005740-B2 Neprilysin inhibitors THERAVANCE BIOPHARMA R&D IP, LLC (US) 2018-06-26 US disclosed
US-20070149810-A1 Vitamin d receptor modulators ELI LILLY AND COMPANY (US) 2007-06-28 US disclosed
US-20070149810-A1 Vitamin d receptor modulators ELI LILLY AND COMPANY (US) 2007-06-28 US disclosed
US-20070106095-A1 Vitamin d receptor modulators ELI LILLY AND COMPANY 2007-05-10 US disclosed
US-20070106095-A1 Vitamin d receptor modulators ELI LILLY AND COMPANY 2007-05-10 US disclosed
EP-0471092-B1 TRIAZOLE COMPOUND AND INSECTICIDE SDS BIOTECH CORP (JP) 1995-09-27 EP disclosed
US-5286738-A Nematocides S.D.S. BIOTECH K.K. (JP) 1994-02-15 US disclosed
US-5208231-A Dialkylcarbamoyl substituted compounds S.D.S. BIOTECH K.K. (JP) 1993-05-04 US disclosed
US-5155124-A TRIAZOLE COMPOUND AND INSECTICIDE COMPOSITION CONTAINING THE SAME S.D.S. BIOTECH K.K. (JP) 1992-10-13 US disclosed
EP-0471092-A1 TRIAZOLE COMPOUND AND INSECTICIDE S.D.S. BIOTECH K.K. (JP) 1992-02-19 EP disclosed
EP-0399553-A1 Triazole compound and insecticide composition containing the same SDS Biotech K.K. (JP) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230111853-A1 COMPOUNDS MODULATING PROTEIN RECRUITMENT AND/OR DEGRADATION CRBN, STUB1, ADRM1 L3MBTL1 2188/4885GLA 3096/4885TSHR 3805/4885
US-20220169611-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer MDM2, TP53, CDKN1A L3MBTL1 3993/4885GLA 2345/4885TSHR 4432/4885
US-11053251-B2 GPR35 modulators GPR35, GPR55, GPR65 L3MBTL1 4058/4885GLA 2411/4885TSHR 1618/4885
US-20210179560-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer MDM2, TP53, CDKN1A L3MBTL1 3993/4885GLA 2345/4885TSHR 4432/4885
US-20070106095-A1 Vitamin d receptor modulators VDR, CYP2R1, CYP24A1 L3MBTL1 4455/4885GLA 2712/4885TSHR 602/4885
US-10005740-B2 Neprilysin inhibitors MME, REN, AGTR1 L3MBTL1 2162/4885GLA 502/4885TSHR 1044/4885
US-20070149810-A1 Vitamin d receptor modulators VDR, CYP2R1, CYP24A1 L3MBTL1 4181/4885GLA 3433/4885TSHR 387/4885
US-20240239809-A1 THERAPEUTIC AGENTS FOR ENHANCING EPITHELIAL AND/OR ENDOTHELIAL BARRIER FUNCTION LIPG, FABP2, EPCAM L3MBTL1 4597/4885GLA 1193/4885TSHR 4301/4885
US-20190133976-A1 METABOLICALLY ROBUST ANALOGS OF CYP-EICOSANOIDS FOR THE TREATMENT OF CARDIAC DISEASE ALOX5, ALOX15, ALOX15B L3MBTL1 3867/4885GLA 957/4885TSHR 2377/4885
US-20200239476-A1 GPR35 MODULATORS GPR35, GPR55, GPR65 L3MBTL1 4058/4885GLA 2411/4885TSHR 1618/4885
US-20210009505-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS CETP, NPC1L1, NPC1 L3MBTL1 566/4885GLA 2890/4885TSHR 1775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.