Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214038 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMMAPK1EPAS1 | |
| SCHEMBL789637 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMMAPK1EPAS1 | |
| SCHEMBL7531612 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMMAPK1EPAS1 | |
| SCHEMBL789155 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMMAPK1EPAS1 | |
| SCHEMBL22389997 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMMAPK1EPAS1 | |
| SCHEMBL24340313 | 0.96 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1PKMMAPK1EPAS1 | |
| SCHEMBL15817493 | 0.92 | — | — | |
| SCHEMBL3814583 | 0.92 | — | — | |
| SCHEMBL8237916 | 0.90 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1PKMMAPK1EPAS1 | |
| SCHEMBL6156333 | 0.90 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1PKMMAPK1EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-03-15 | — | — | US | disclosed |
| US-20160122307-A1 | PERHYDROQUINOXALINE DERIVATIVES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2016-05-05 | — | — | US | disclosed |
| EP-2997025-A1 | PERHYDROQUINOXALINE DERIVATIVES USEFUL AS ANALGESICS | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2016-03-23 | — | — | EP | disclosed |
| EP-2217226-B1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2015-07-22 | — | — | EP | disclosed |
| EP-2283004-B1 | AMIDO-THIOPHENE COMPOUNDS AND THEIR USE | UNIV EDINBURGH (GB) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014184355-A1 | PERHYDROQUINOXALINE DERIVATIVES USEFUL AS ANALGESICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014184356-A1 | PERHYDROQUINOXALINE DERIVATIVES USEFUL AS ANALGESICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2014-11-20 | — | — | WO | disclosed |
| US-8614209-B2 | Amido-thiophene compounds and their use | THE UNIVERSITY OF EDINBURGH (GB) | 2013-12-24 | — | — | US | disclosed |
| US-20130045962-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2013-02-21 | — | — | US | disclosed |
| US-20130012545-A1 | Amido-Thiophene Compounds and Their Use | THE UNIVERSITY OF EDINBURGH (GB) | 2013-01-10 | — | — | US | disclosed |
| US-20110015178-A1 | Amido-Thiophene Compounds and Their Use | THE UNIVERSITY OF EDINBURGH (GB) | 2011-01-20 | — | — | US | disclosed |
| EP-2217226-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20090306066-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2009-12-10 | — | — | US | disclosed |
| WO-2009061879-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| WO-2008005368-A2 | PIPERAZINES AS P2X7 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2008-01-10 | — | — | WO | disclosed |
| EP-1177190-B1 | USE OF SELECTIVE ANTAGONISTS OF THE ALPHA 1b-ADRENERGIC RECEPTOR FOR IMPROVEMENT OF SEXUAL DYSFUNCTION | RECORDATI CHEM PHARM (IT) | 2005-11-02 | — | — | EP | disclosed |
| US-6953800-B2 | Use of selective antagonists of the α1B-adrenergic receptor for improvement of sexual dysfunction | RECORDATI S.A. CHEMICAL (CH) | 2005-10-11 | — | — | US | disclosed |
| US-20020161009-A1 | Use of selective antagonists of the alpha1b-adrenergic receptor for improvement of sexual dysfunction | RECORDATI S.A. | 2002-10-31 | — | — | US | disclosed |
| US-6303606-B1 | FOR THERAPY OF SEXUAL DISORDERS | RECORDATI, S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2001-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | CRH, MC2R, HTR3C | L3MBTL1 303/4885ALDH1A1 1739/4885PKM 1398/4885 |
| US-20020161009-A1 | Use of selective antagonists of the alpha1b-adrenergic receptor for improvement of sexual dysfunction | ADRA1B, ADRA2B, ADRB2 | L3MBTL1 2916/4885ALDH1A1 687/4885PKM 3655/4885 |
| US-20110015178-A1 | Amido-Thiophene Compounds and Their Use | HSD11B1, HSD11B2, HSD17B1 | L3MBTL1 2996/4885ALDH1A1 328/4885PKM 1305/4885 |
| US-20130045962-A1 | PEPTIDE DEFORMYLASE INHIBITORS | PDF, DPEP1, DHPS | L3MBTL1 2039/4885ALDH1A1 985/4885PKM 2293/4885 |
| US-20160122307-A1 | PERHYDROQUINOXALINE DERIVATIVES | PTGS1, HPGD, HMOX1 | L3MBTL1 4718/4885ALDH1A1 372/4885PKM 581/4885 |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | P2RX7, P2RX1, P2RX2 | L3MBTL1 4681/4885ALDH1A1 852/4885PKM 1302/4885 |
| US-20090306066-A1 | PEPTIDE DEFORMYLASE INHIBITORS | PDF, DHPS, PADI3 | L3MBTL1 1277/4885ALDH1A1 1567/4885PKM 1508/4885 |
| US-20130012545-A1 | Amido-Thiophene Compounds and Their Use | HSD11B1, HSD11B2, HSD17B1 | L3MBTL1 2996/4885ALDH1A1 328/4885PKM 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.