Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467670 | 0.98 | KDM4E (0.32) | IDO1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL15953455 | 0.98 | KDM4E (0.32) | IDO1KDM4EMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL17092521 | 0.78 | APP (0.34) | KDM4EMEN1ALDH1A1KMT2AMMP2 | |
| Biphenyl SCHEMBL28193720 | 0.76 | ALDH1A1 (0.43) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL27465208 | 0.75 | — | — | |
| Benzene SCHEMBL9464137 | 0.74 | KDM4E (0.30) | KDM4EMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL4542347 | 0.74 | GAA (0.37) | IDO1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3337845 | 0.74 | GAA (0.37) | IDO1KDM4EALDH1A1 | |
| Toluene SCHEMBL5492947 | 0.73 | TSHR (0.44) | IDO1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8424143 | 0.72 | APP (0.35) | IDO1KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11867873-B2 | Method for producing multilayer optical film | ZEON CORPORATION (JP) | 2024-01-09 | — | — | US | disclosed |
| US-11709302-B2 | Phase difference film and production method for the same | ZEON CORPORATION (JP) | 2023-07-25 | — | — | US | disclosed |
| US-11346991-B2 | Phase difference film and production method for the same | ZEON CORPORATION (JP) | 2022-05-31 | — | — | US | disclosed |
| US-20210364672-A1 | METHOD FOR PRODUCING MULTILAYER OPTICAL FILM | ZEON CORPORATION (JP) | 2021-11-25 | — | — | US | disclosed |
| US-10882244-B2 | Resin film, barrier film, and electrically conductive film, and production methods therefor | ZEON CORPORATION (JP) | 2021-01-05 | — | — | US | disclosed |
| US-20200292742-A1 | PHASE DIFFERENCE FILM AND PRODUCTION METHOD FOR THE SAME | ZEON CORPORATION (JP) | 2020-09-17 | — | — | US | disclosed |
| US-10759917-B2 | Conductive film and method for producing same | ZEON CORPORATION (JP) | 2020-09-01 | — | — | US | disclosed |
| US-10712487-B2 | Phase difference film and production method for the same | ZEON CORPORATION (JP) | 2020-07-14 | — | — | US | disclosed |
| US-10605972-B2 | Long film and method for producing same | ZEON CORPORATION (JP) | 2020-03-31 | — | — | US | disclosed |
| US-10603878-B2 | Optical laminate, method for producing same, polarizing plate, and display device | ZEON CORPORATION (JP) | 2020-03-31 | — | — | US | disclosed |
| EP-2305729-A1 | Hydrogenated norbornene-based ring-opening polymerization polymer, resin composition, and molded object | Zeon Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-20110021731-A1 | HYDROGENATED CRYSTALLINE NORBORNENE RING-OPENING POLYMER AND MOLDED ARTICLE | ZEON CORPORATION (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2248839-A1 | CRYSTALLINE NORBORNENE RING-OPENING POLYMER HYDRIDE AND MOLDED ARTICLE OF SAME | Zeon Corporation (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100092712-A1 | POLYMER COMPOSITION AND USE THEREOF | ZEON CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20100076396-A1 | HYDROGENATED NORBORNENE-BASED RING-OPENING POLYMERIZATION POLYMER, RESIN COMPOSITION, AND MOLDED OBJECT | ZEON CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2128196-A1 | POLYMER COMPOSITION AND USE THEREOF | ZEON CORPORATION (JP) | 2009-12-02 | — | — | EP | disclosed |
| EP-2058350-A1 | HYDROGENATED NORBORNENE-BASED RING-OPENING POLYMERIZATION POLYMERS, RESIN COMPOSITION, AND MOLDED OBJECTS | ZEON CORPORATION (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-1238996-B1 | NORBORNENE OPEN-RING POLYMERS, PRODUCTS OF HYDROGENATION THEREOF AND PROCESSES FOR THE PRODUCTION OF BOTH | ZEON CORP (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6653424-B1 | Using polymerization catalyst comprising transition metal imide of Group 6 substituted by alkyloxy, aryloxy, alkylamide and/or arylamide groups; high melting | ZEON CORPORATION (JP) | 2003-11-25 | — | — | US | disclosed |
| EP-1238996-A1 | NORBORNENE OPEN-RING POLYMERS, PRODUCTS OF HYDROGENATION THEREOF AND PROCESSES FOR THE PRODUCTION OF BOTH | Zeon Corporation (JP) | 2002-09-11 | — | — | EP | disclosed |