Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glyphosate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | ENO1 | P06733 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | GGH | Q92820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glyphosate SCHEMBL10482417 | 0.98 | LMNA (0.40) | LMNAMEN1HPGDTSHRBLM | |
| Glyphosate SCHEMBL8515704 | 0.97 | LMNA (0.43) | LMNAMEN1HPGDTSHRBLM | |
| Glyphosate SCHEMBL30579950 | 0.97 | LMNA (0.43) | LMNAMEN1HPGDTSHRBLM | |
| Glyphosate SCHEMBL1964442 | 0.97 | LMNA (0.43) | LMNAMEN1HPGDTSHRBLM | |
| Glyphosate SCHEMBL16440 | 0.97 | LMNA (0.43) | LMNAMEN1HPGDTSHRBLM | |
| Glyphosate SCHEMBL30579951 | 0.97 | LMNA (0.43) | LMNAMEN1HPGDTSHRBLM | |
| Glyphosate SCHEMBL214438 | 0.97 | LMNA (0.43) | LMNAMEN1HPGDTSHRBLM | |
| Glyphosate SCHEMBL29694166 | 0.97 | LMNA (0.43) | LMNAMEN1HPGDTSHRBLM | |
| Glyphosate SCHEMBL63406 | 0.95 | LMNA (0.42) | LMNAMEN1HPGDTSHRBLM | |
| Glyphosate SCHEMBL10482432 | 0.95 | LMNA (0.42) | LMNAMEN1HPGDTSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100567311-C | The continuous synthetic method of a kind of glyphosate by dimethyl ester | XIN AN CHEMICAL GROUP CO LTD (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-1939927-A | Continuous synthesis of glyphosate by dimethyl ester | XIN AN CHEMICAL GROUP CO LTD Z (CN) | 2007-04-04 | — | — | CN | claimed |
| CN-119751502-A | Glyphosate crystallization method for eliminating fine crystals and edges and corners and application thereof | 中国科学院过程工程研究所 | 2025-04-04 | — | — | CN | disclosed |
| CN-110922426-B | Alkyl ester method glyphosate continuous production system and process | 湖北泰盛化工有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-113072580-A | Method for recovering glyphosate from glyphosate acid mother liquor by glycine method | 浙江新安化工集团股份有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-211057000-U | Glycine method glyphosate serialization apparatus for producing that hydrolysises | 湖北泰盛化工有限公司 | 2020-07-21 | — | — | CN | disclosed |
| CN-110922426-A | Alkyl ester method glyphosate continuous production system and process | 湖北泰盛化工有限公司 | 2020-03-27 | — | — | CN | disclosed |
| CN-106632470-B | The synthesis of N- methylol glyphosate or its ester and its method for preparing glyphosate | 武汉工程大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-106632470-B | The synthesis of N- methylol glyphosate or its ester and its method for preparing glyphosate | 武汉工程大学 | 2019-02-01 | — | — | CN | disclosed |
| US-9676799-B2 | Method for the synthesis of N-(phosphonomethyl)glycine | STRAITMARK HOLDING AG (CH) | 2017-06-13 | — | — | US | disclosed |
| CN-106632470-A | Synthesis of N-hydroxymethyl glyphosate or ester thereof and method for preparing glyphosate | 武汉工程大学 | 2017-05-10 | — | — | CN | disclosed |
| EP-2875037-A1 | METHOD FOR THE SYNTHESIS OF N-(PHOSPHONOMETHYL)GLYCINE | Straitmark Holding AG (CH) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014012991-A1 | METHOD FOR THE SYNTHESIS OF N-(PHOSPHONOMETHYL)GLYCINE | STRAITMARK HOLDING AG (CH) | 2014-01-23 | — | — | WO | disclosed |
| CN-100443490-C | Process for preparing glyphosate | XUEFENG WANG (CN) | 2008-12-17 | — | — | CN | disclosed |
| CN-1308336-C | Process for treating production mother liquor of glyphosate | HANGZHOU JINFADA CHEMICAL INDU (CN) | 2007-04-04 | — | — | CN | disclosed |
| CN-1935816-A | Process for preparing glyphosate | WANG XUEFENG (CN) | 2007-03-28 | — | — | CN | disclosed |
| CN-1657531-A | Process for treating production mother liquor of glyphosate | HANGZHOU JINFADA CHEMICAL INDU (CN) | 2005-08-24 | — | — | CN | disclosed |
| EP-0186648-B2 | PROCESS FOR THE PREPARATION OF GLYPHOSATE AND GLYPHOSATE DERIVATIVES | Monsanto Company (US) | 1992-09-02 | — | — | EP | disclosed |
| EP-0186648-B1 | PROCESS FOR THE PREPARATION OF GLYPHOSATE AND GLYPHOSATE DERIVATIVES | Monsanto Company (US) | 1990-02-28 | — | — | EP | disclosed |
| EP-0186648-A1 | Process for the preparation of glyphosate and glyphosate derivatives | Monsanto Company (US) | 1986-07-02 | — | — | EP | disclosed |