Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28281485 | 0.92 | L3MBTL1 (0.41) | L3MBTL1ADH1ALMNAALDH1A1PTBP1 | |
| SCHEMBL15283941 | 0.83 | L3MBTL1 (0.34) | L3MBTL1HSD11B1LMNAPYGLMEN1 | |
| SCHEMBL628951 | 0.83 | L3MBTL1 (0.42) | L3MBTL1ADH1AHSD11B1THRATHRB | |
| SCHEMBL10777585 | 0.83 | L3MBTL1 (0.45) | L3MBTL1ADH1AHSD11B1LMNAALDH1A1 | |
| SCHEMBL12198758 | 0.81 | L3MBTL1 (0.43) | L3MBTL1ADH1AHSD11B1LMNAALDH1A1 | |
| SCHEMBL21679937 | 0.80 | SLC18A3 (0.34) | L3MBTL1 | |
| SCHEMBL5510945 | 0.80 | L3MBTL1 (0.42) | L3MBTL1ADH1AHSD11B1THRATHRB | |
| SCHEMBL9299854 | 0.78 | SPR (0.38) | LMNAALDH1A1PYGL | |
| SCHEMBL9071877 | 0.78 | L3MBTL1 (0.41) | L3MBTL1ADH1AHSD11B1THRATHRB | |
| SCHEMBL19478023 | 0.78 | EPHX2 (0.33) | HSD11B1THRATHRBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220202658-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2022-06-30 | — | — | US | disclosed |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | DENTSPLY SIRONA INC. (US) | 2022-02-03 | — | — | US | disclosed |
| US-11224557-B2 | Dental composition | DENTSPLY SIRONA INC (US) | 2022-01-18 | — | — | US | disclosed |
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DENTSPLY SIRONA INC. (US) | 2022-01-06 | — | — | US | disclosed |
| US-11141357-B2 | Dental adhesive | DENTSPLY SIRONA INC. (US) | 2021-10-12 | — | — | US | disclosed |
| US-11116702-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20210137795-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2021-05-13 | — | — | US | disclosed |
| US-20210106503-A1 | DENTAL IMPRESSION MATERIAL | DENTSPLY SIRONA INC. (US) | 2021-04-15 | — | — | US | disclosed |
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2010-06-24 | — | — | US | disclosed |
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2010-06-24 | — | — | US | disclosed |
| US-20100022682-A1 | Dental adhesive composition | KLEE JOACHIM E | 2010-01-28 | — | — | US | disclosed |
| US-20100022682-A1 | Dental adhesive composition | KLEE JOACHIM E | 2010-01-28 | — | — | US | disclosed |
| US-20090043008-A1 | Dental adhesive | KLEE JOACHIM E | 2009-02-12 | — | — | US | disclosed |
| US-20090043008-A1 | Dental adhesive | KLEE JOACHIM E | 2009-02-12 | — | — | US | disclosed |
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2008-08-14 | — | — | US | disclosed |
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2008-08-14 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11224557-B2 | Dental composition | GPX4, GPX1, NOXO1 | L3MBTL1 4596/4885ADH1A 3654/4885HSD11B1 2839/4885 |
| US-11141357-B2 | Dental adhesive | CDH1, ITGA5, ICAM1 | L3MBTL1 4238/4885ADH1A 786/4885HSD11B1 4632/4885 |
| US-20220202658-A1 | DENTAL COMPOSITION | CAD, PHOSPHO1, PLA2G2C | L3MBTL1 4589/4885ADH1A 1293/4885HSD11B1 4135/4885 |
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DUOX2, DUOX1, QSOX1 | L3MBTL1 2913/4885ADH1A 558/4885HSD11B1 2751/4885 |
| US-20210106503-A1 | DENTAL IMPRESSION MATERIAL | FHIT, PASK, TAS2R40 | L3MBTL1 3302/4885ADH1A 2661/4885HSD11B1 3383/4885 |
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | PPA1, PHOSPHO1, PDAP1 | L3MBTL1 4315/4885ADH1A 843/4885HSD11B1 3549/4885 |
| US-20210137795-A1 | DENTAL ADHESIVE | CDH1, ITGA5, ICAM1 | L3MBTL1 4238/4885ADH1A 786/4885HSD11B1 4632/4885 |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DHX35, DHX30, FLNA | L3MBTL1 4592/4885ADH1A 2603/4885HSD11B1 3062/4885 |
| US-11116702-B2 | Dental composition | MTR, CAD, PAM | L3MBTL1 4248/4885ADH1A 1473/4885HSD11B1 3101/4885 |
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | PPA1, PHOSPHO1, PDAP1 | L3MBTL1 4315/4885ADH1A 843/4885HSD11B1 3549/4885 |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | CAD, ASIC1, PDAP1 | L3MBTL1 3984/4885ADH1A 504/4885HSD11B1 3938/4885 |
| US-20090043008-A1 | Dental adhesive | H1-0, H1-2, ITGA1 | L3MBTL1 3368/4885ADH1A 451/4885HSD11B1 1998/4885 |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | FLNA, FLNB, SAMM50 | L3MBTL1 1438/4885ADH1A 2411/4885HSD11B1 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.