Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR known ✓ | P02766 | 1/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.35 |
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.35 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.57 |
| ▸ | ACACB | O00763 | 1/20 | 0.55 |
| ▸ | ACACA | Q13085 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL561963 | 1.00 | ACLY (0.57) | ACLYACACBACACATBXAS1TDP1 | |
| Hydrochloric Acid SCHEMBL562371 | 0.98 | ACLY (0.53) | ACLYACACBACACATBXAS1TDP1 | |
| SCHEMBL250911 | 0.98 | ACLY (0.59) | ACLYACACBACACATBXAS1TDP1 | |
| Hydrochloric Acid SCHEMBL621977 | 0.98 | ACLY (0.53) | ACLYACACBACACATBXAS1TDP1 | |
| SCHEMBL154712 | 0.96 | ACLY (0.55) | ACLYACACBACACATBXAS1TDP1 | |
| Hydrochloric Acid SCHEMBL561986 | 0.91 | ACLY (0.50) | ACLYACACBACACATBXAS1TDP1 | |
| Hydrochloric Acid SCHEMBL2867978 | 0.91 | ACLY (0.50) | ACLYACACBACACATBXAS1TDP1 | |
| SCHEMBL232205 | 0.89 | ACLY (0.52) | ACLYACACBACACATBXAS1TDP1 | |
| Octadecanoic Acid Amide SCHEMBL5012035 | 0.88 | SOAT1 (0.46) | ACLYACACBACACATDP1FFAR1 | |
| Hydrochloric Acid SCHEMBL561964 | 0.87 | SOAT1 (0.41) | ACLYACACBACACATBXAS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133318-B1 | SUPRAMOLECULAR COMPLEXES CONTAINING THERAPEUTIC AGENTS | CALIFORNIA INST OF TECHN (US) | 2007-03-14 | — | — | EP | claimed |
| EP-0832201-B1 | A SAMPLE PRESENTATION APPARATUS FOR MASS SPECTROMETRY | UNIV ARIZONA (US) | 2005-10-05 | — | — | EP | claimed |
| EP-1131281-B1 | DERIVATISATION OF SUPPORT SURFACES | DEUTSCHES KREBSFORSCH (DE) | 2005-07-27 | — | — | EP | claimed |
| US-6905724-B1 | Derivatization of support surfaces | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2005-06-14 | — | — | US | claimed |
| US-20030148304-A1 | Method for immobilisation | KAROLINSKA INNOVATIONS AB (SE) | 2003-08-07 | — | — | US | claimed |
| EP-1235937-A1 | METHOD FOR IMMOBILISATION | Karolinska Innovations AB (SE) | 2002-09-04 | — | — | EP | claimed |
| WO-2001042501-A1 | METHOD FOR IMMOBILISATION | KAROLINSKA INNOVATIONS AB (SE) | 2001-06-14 | — | — | WO | claimed |
| US-6093541-A | WITH METAL PRESENTATION SURFACE HAVING IMMOBILIZED COMPLEX OF TETHERING MOLECULE AND DIGESTION MOLECULE; FOR RAPID AND EFFICIENT ANALYSIS OF BIOMOLECULES USING MATRIX-ASSISTED LASER DESORPTION/IONIZATION TECHNIQUE | ARIZONA STATE UNIVERSITY BOARD OF REGENTS (US) | 2000-07-25 | — | — | US | claimed |
| US-6004770-A | MASS SPECTROMETRY SAMPLE PRESENTATION APPARATUSES DERIVATIZED WITH COMPLEXES INCLUDING AT LEAST ONE MOLECULE WHICH MODIFIES A BIOMOLECULE | ARIZONA STATE UNIVERSITY BOARD OF REGENTS (US) | 1999-12-21 | — | — | US | claimed |
| EP-0184710-A2 | Magnetic microspheres | BAYER AG (DE) | 1986-06-18 | — | — | EP | claimed |
| US-20250296984-A1 | THERAPEUTIC AND DIAGNOSTIC AGENTS AND USES THEREOF | THELPER AS (NO) | 2025-09-25 | — | — | US | disclosed |
| EP-4472663-A1 | THERAPEUTIC AND DIAGNOSTIC AGENTS AND USES THEREOF | THELPER AS (NO) | 2024-12-11 | — | — | EP | disclosed |
| US-20240199724-A1 | THERAPEUTIC AND DIAGNOSTIC AGENTS AND USES THEREOF | THELPER AS (NO) | 2024-06-20 | — | — | US | disclosed |
| EP-2961395-B1 | TARGETED NANOPARTICLES | CALIFORNIA INST OF TECHN (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023190243-A1 | METHOD FOR PREPARING SUPRAMOLECULAR HYDROGEL, AND APPLICATION AS BIOMATERIAL | デンカ株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-1996040888-A1 | A SAMPLE PRESENTATION APPARATUS FOR MASS SPECTROMETRY | ARIZONA BOARD OF REGENTS (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0745602-A1 | Quinidine immunoassay and reagents | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-04 | — | — | EP | disclosed |
| US-4053590-A | BLOOD SUBSTITUTE, PLASMA EXPANDER | ALZA CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-4001200-A | BLOOD SUBSTITUTE FOR CARRYING OXYGEN | ALZA CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-4001401-A | BLOOD SUBSTITUTE AND BLOOD PLASMA EXPANDER COMPRISING POLYHEMOGLOBIN | ALZA CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |