Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 6/20 | 0.41 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 5/20 | 0.41 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.41 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.41 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylamine SCHEMBL4661752 | 0.90 | ACLY (0.55) | MEN1KMT2AACLYACACBACACA | |
| Hydrochloric Acid SCHEMBL561963 | 0.88 | ACLY (0.57) | SOAT1MEN1KMT2AACLYFAAH | |
| Hydrochloric Acid SCHEMBL1175992 | 0.88 | ACLY (0.57) | SOAT1MEN1KMT2AACLYFAAH | |
| Hydrochloric Acid SCHEMBL562371 | 0.86 | ACLY (0.53) | SOAT1MEN1KMT2AACLYFAAH | |
| Hydrochloric Acid SCHEMBL621977 | 0.86 | ACLY (0.53) | SOAT1MEN1KMT2AACLYFAAH | |
| SCHEMBL250911 | 0.86 | ACLY (0.59) | SOAT1MEN1KMT2AACLYFAAH | |
| SCHEMBL154712 | 0.84 | ACLY (0.55) | SOAT1MEN1KMT2AACLYFAAH | |
| Propylamine SCHEMBL28101610 | 0.83 | SMPD1 (0.46) | MEN1KMT2ASMPD1FDPSTSHR | |
| Hydrochloric Acid SCHEMBL27951861 | 0.82 | ACLY (0.59) | MEN1KMT2AACLYACACBACACA | |
| Hydrochloric Acid SCHEMBL3666230 | 0.82 | ACLY (0.59) | MEN1KMT2AACLYACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070196403-A1 | Anhydrous cosmetic compositions | UCHIDA MIKIO | 2007-08-23 | — | — | US | claimed |
| US-8648023-B2 | Process for inhibiting dyed hair fibers from losing their color during shampooing | L'ORÉAL (FR) | 2014-02-11 | — | — | US | disclosed |
| US-20120269756-A1 | PROCESS FOR INHIBITING DYED HAIR FIBERS FROM LOSING THEIR COLOR DURING SHAMPOOING | L'ORÉAL (FR) | 2012-10-25 | — | — | US | disclosed |
| US-7449029-B2 | Composition and process for color hair | L'OREAL (FR) | 2008-11-11 | — | — | US | disclosed |
| US-20070196403-A1 | Anhydrous cosmetic compositions | UCHIDA MIKIO | 2007-08-23 | — | — | US | disclosed |
| US-20070107142-A1 | Composition and process for coloring hair | L'OREAL (FR) | 2007-05-17 | — | — | US | disclosed |
| US-6946122-B2 | Hair care composition containing a polyalkylene (n) alkylamine which provide hair volume reduction | THE PROCTER & GAMBLE COMPANY (US) | 2005-09-20 | — | — | US | disclosed |
| US-6730292-B1 | REDUCES FLYAWAY EFFECT AND BULK VOLUME; BIODEGRADABLE; NONOILY FEEL | THE PROCTER & GAMBLE COMPANY | 2004-05-04 | — | — | US | disclosed |
| US-20030206883-A1 | Hair care composition containing a polyalkylene (n) alkylamine which provide hair volume reduction | PROCTER & GAMBLE COMPANY, THE | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120269756-A1 | PROCESS FOR INHIBITING DYED HAIR FIBERS FROM LOSING THEIR COLOR DURING SHAMPOOING | SRM, SMS, SMOX | PPARG 3701/4885HDAC11 293/4885ESR1 4712/4885 |
| US-20070196403-A1 | Anhydrous cosmetic compositions | H1-0, CUTA, TRPA1 | PPARG 434/4885HDAC11 708/4885ESR1 3549/4885 |
| US-20030206883-A1 | Hair care composition containing a polyalkylene (n) alkylamine which provide hair volume reduction | CS, POLR1C, SLC6A12 | PPARG 623/4885HDAC11 516/4885ESR1 4611/4885 |
| US-20070107142-A1 | Composition and process for coloring hair | SRM, SMOX, SMS | PPARG 4402/4885HDAC11 324/4885ESR1 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.