Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111141 | 0.97 | — | — | |
| SCHEMBL30203079 | 0.97 | — | — | |
| SCHEMBL31116914 | 0.95 | — | — | |
| SCHEMBL27579426 | 0.95 | — | — | |
| Iodide SCHEMBL5852421 | 0.95 | — | — | |
| Formaldehyde SCHEMBL29049926 | 0.91 | NFE2L2 (0.41) | — | |
| Methylene Chloride SCHEMBL28246161 | 0.91 | P2RX7 (0.40) | — | |
| Pyridine SCHEMBL28119217 | 0.87 | NPC1 (0.39) | — | |
| Acetamide SCHEMBL28246885 | 0.83 | MKNK1 (0.47) | — | |
| SCHEMBL28283437 | 0.79 | HPGD (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088010-A1 | MONODISPERSE, MACROPOROUS CHELATING RESINS IN METAL WINNING | LANXESS DEUTSCHLAND GMBH (DE) | 2007-08-09 | — | — | WO | claimed |
| US-20040000523-A1 | Silica-polyamine extraction material | ROSENBERG EDWARD (US) | 2004-01-01 | — | — | US | claimed |
| US-6576590-B2 | Silica-polyamine based extraction material removes selected transition metal ions from solution in the presence of iron ions | UNIVERSITY OF MONATAN | 2003-06-10 | — | — | US | claimed |
| US-20020139753-A1 | Silica-polyamine based extraction material removes selected transition metal ions from solution in the presence of iron ions | NATIONAL SCIENCE FOUNDATION | 2002-10-03 | — | — | US | claimed |
| WO-2002061157-A2 | SILICA-POLYAMINE BASED EXTRACTION MATERIALS FOR THE SEPARATION OF COPPER IONS AND FERRIC IRON IN AQUEOUS LEACH LIQUIDS | THE UNIVERSITY OF MONTANA (US) | 2002-08-08 | — | — | WO | claimed |
| EP-0427161-B1 | Picolylselenobenzamides of aminopyridines, anilines and picolylamines | NATTERMANN A & CIE (DE) | 1994-04-20 | — | — | EP | claimed |
| EP-0427161-A1 | Picolylselenobenzamides of aminopyridines, anilines and picolylamines | A. Nattermann & Cie. GmbH (DE) | 1991-05-15 | — | — | EP | claimed |
| EP-3325467-A1 | SUBSTITUTED HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-30 | — | — | EP | disclosed |
| EP-2025387-B1 | METHOD FOR PRODUCING MONODISPERSE CHELATE RESIN | LANXESS DEUTSCHLAND GMBH (DE) | 2018-04-18 | — | — | EP | disclosed |
| WO-2017012965-A1 | SUBSTITUTED HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-01-26 | — | — | WO | disclosed |
| CN-101880460-B | Conductive composition and process for producing the same | SHIN-ETSU POLYMER CO., LTD. (JP) | 2011-12-28 | — | — | CN | disclosed |
| CN-101113238-B | Conductive composition, and process for producing the same | SHINETSU POLYMER CO | 2011-09-28 | — | — | CN | disclosed |
| EP-2040266-B1 | Absorption of radionuclides | LANXESS DEUTSCHLAND GMBH (DE) | 2011-04-27 | — | — | EP | disclosed |
| US-4564681-A | Production of mixtures rich in 3-chloro-2-trichloromethyl pyridine | KALAMA CHEMICAL, INC. (US) | 1986-01-14 | — | — | US | disclosed |
| EP-0144323-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL, INC. (US) | 1985-06-19 | — | — | EP | disclosed |
| EP-0139648-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL, INC. (US) | 1985-05-08 | — | — | EP | disclosed |
| US-4487935-A | GOOD MIXING, MULTISTAGE | KALAMA CHEMICAL, INC. (US) | 1984-12-11 | — | — | US | disclosed |
| US-4483993-A | MULTISTAGE CHLORINATION | KALAMA CHEMICAL, INC. (US) | 1984-11-20 | — | — | US | disclosed |
| WO-1984004095-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL INC (US) | 1984-10-25 | — | — | WO | disclosed |
| WO-1984004094-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL INC (US) | 1984-10-25 | — | — | WO | disclosed |