Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.47 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | EP300 | Q09472 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353534 | 0.98 | HTT (0.63) | HTTLMNAEP300MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL10719596 | 0.78 | PKM (0.61) | HTTEP300KDM4EHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL5691548 | 0.78 | PKM (0.61) | HTTEP300KDM4EHSD17B10TP53 | |
| SCHEMBL866443 | 0.78 | CYP1A2 (0.43) | HTTLMNAEP300KDM4EGAA | |
| SCHEMBL1562090 | 0.78 | CYP1A2 (0.50) | LMNAEP300KDM4EGAAHSD17B10 | |
| SCHEMBL29999289 | 0.78 | CYP1A2 (0.50) | LMNAEP300KDM4EGAAHSD17B10 | |
| SCHEMBL29462977 | 0.78 | CYP1A2 (0.43) | HTTLMNAEP300KDM4EGAA | |
| SCHEMBL352532 | 0.76 | PKM (0.63) | HTTLMNAEP300MAPTKDM4E | |
| SCHEMBL29405295 | 0.76 | PKM (0.63) | HTTLMNAEP300MAPTKDM4E | |
| Vitamin K3H2 SCHEMBL297164 | 0.76 | HTT (1.00) | HTTLMNAEP300MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150283290-A1 | STERILIZED COMPOSITIONS OF CYANOACRYLATE MONOMERS AND NAPHTHOQUINONE 2,3-OXIDES | ADHEZION BIOMEDICAL, LLC (US) | 2015-10-08 | — | — | US | claimed |
| US-4764201-A | Plant growth regulation | TOMOE KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-08-16 | — | — | US | claimed |
| JP-62190101-A | — | — | None | — | — | JP | disclosed |
| JP-62190102-A | — | — | None | — | — | JP | disclosed |
| JP-62192302-A | — | — | None | — | — | JP | disclosed |
| JP-4046103-A | — | — | None | — | — | JP | disclosed |
| US-9717699-B2 | Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides | ADHEZION BIOMEDICAL, LLC (US) | 2017-08-01 | — | — | US | disclosed |
| US-20160331700-A1 | Sterilized Compositions of Cyanoacrylate Monomers and Naphthoquinone 2,3-Oxides | H.B. FULLER MEDICAL ADHESIVE TECHNOLOGIES, LLC. | 2016-11-17 | — | — | US | disclosed |
| US-9421297-B2 | Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides | ADHEZION BIOMEDICAL, LLC (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150283290-A1 | STERILIZED COMPOSITIONS OF CYANOACRYLATE MONOMERS AND NAPHTHOQUINONE 2,3-OXIDES | ADHEZION BIOMEDICAL, LLC (US) | 2015-10-08 | — | — | US | disclosed |
| EP-2305224-B1 | Vitamin K analog for treatment of skin or mucosal ulceration | EINSTEIN COLL MED (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-1538136-B1 | Fertilizer composition to stimulate the absorption of nutritive substances in plants | VALAGRO SPA (IT) | 2006-03-08 | — | — | EP | disclosed |
| WO-2005054156-A1 | FERTILIZER COMPOSITION TO STIMULATE THE ABSORPTION OF NUTRITIVE SUBSTANCES IN PLANTS | VALAGRO S.P.A. (IT) | 2005-06-16 | — | — | WO | disclosed |
| EP-1538136-A1 | Fertilizer composition to stimulate the absorption of nutritive substances in plants | Valagro S.p.A. (IT) | 2005-06-08 | — | — | EP | disclosed |
| US-20050119127-A1 | Fertilizer composition to stimulate the absorption of nutritive substances in plants | VALAGRO S.P.A. (IT) | 2005-06-02 | — | — | US | disclosed |
| JP-H0446103-A | GROWTH ACTIVATING AGENT OF CROP FOR AGRICULTURE AND HORTICULTURE AND METHOD FOR REDUCING PHYTOTOXICITY BY HERBICIDE | TOMOE KAGAKU KOGYO KK | 1992-02-17 | — | — | JP | disclosed |
| US-4764201-A | Plant growth regulation | TOMOE KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-08-16 | — | — | US | disclosed |
| JP-S62192302-A | STOCK HYPODYNAMIC INHIBITOR FOR STRAWBERRY | TOMOE KAGAKU KOGYO KK | 1987-08-22 | — | — | JP | disclosed |
| JP-S62190102-A | ADDITIVE FOR SEEDLING RAISING MAT OF PADDY RICE PLANT | TOMOE KAGAKU KOGYO KK | 1987-08-20 | — | — | JP | disclosed |
| JP-S62190101-A | MATURITY PROMOTER FOR AGRICULTURAL AND HORTICULTURAL CROP | TOMOE KAGAKU KOGYO KK | 1987-08-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160331700-A1 | Sterilized Compositions of Cyanoacrylate Monomers and Naphthoquinone 2,3-Oxides | PROC, CCNK, MMS19 | GAA 4091/4885HDAC3 3820/4885HTT 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.