Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488607 | 0.77 | KDM4E (0.58) | KDM4EGPR3ALDH1A1MAPTNPC1 | |
| SCHEMBL2406867 | 0.77 | KDM4E (0.54) | KDM4EGPR3ALDH1A1MAPTNPC1 | |
| SCHEMBL30598019 | 0.77 | KDM4E (0.54) | KDM4EGPR3ALDH1A1MAPTNPC1 | |
| SCHEMBL13192813 | 0.75 | LMNA (0.52) | KDM4EALDH1A1MAPTNPC1TP53 | |
| SCHEMBL29077538 | 0.75 | KDM4E (0.52) | KDM4EGPR3ALDH1A1MAPTNPC1 | |
| SCHEMBL28661854 | 0.75 | KDM4E (0.52) | KDM4EGPR3ALDH1A1MAPTNPC1 | |
| SCHEMBL31318624 | 0.75 | KDM4E (0.52) | KDM4EGPR3ALDH1A1MAPTNPC1 | |
| Water SCHEMBL8370901 | 0.75 | KDM4E (0.52) | KDM4EGPR3ALDH1A1MAPTNPC1 | |
| SCHEMBL3092457 | 0.73 | KDM4E (0.61) | KDM4EGPR3ALDH1A1MAPTNPC1 | |
| SCHEMBL29211322 | 0.73 | KDM4E (0.45) | KDM4EGPR3ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | SFC CO., LTD. (KR) | 2023-08-03 | — | — | US | disclosed |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | SFC CO., LTD. (KR) | 2023-08-03 | — | — | US | disclosed |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | SFC CO., LTD. (KR) | 2023-06-06 | — | — | US | disclosed |
| US-10100053-B2 | Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-b]pyrazin-3-one derivatives | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-10-16 | — | — | US | disclosed |
| EP-3074395-B1 | PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES | CANCER RESEARCH TECH LTD (GB) | 2018-08-22 | — | — | EP | disclosed |
| US-10014479-B2 | Organic light-emitting diode with high efficiency and long lifetime | SFC CO., LTD. (KR) | 2018-07-03 | — | — | US | disclosed |
| US-10014479-B2 | Organic light-emitting diode with high efficiency and long lifetime | SFC CO., LTD. (KR) | 2018-07-03 | — | — | US | disclosed |
| US-9947877-B2 | Organic light emitting display device | LG DISPLAY CO., LTD. (KR) | 2018-04-17 | — | — | US | disclosed |
| US-9947877-B2 | Organic light emitting display device | LG DISPLAY CO., LTD. (KR) | 2018-04-17 | — | — | US | disclosed |
| US-20170298065-A1 | PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2017-10-19 | — | — | US | disclosed |
| US-20170222160-A1 | ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME | SFC CO., LTD. (KR) | 2017-08-03 | — | — | US | disclosed |
| US-20170222160-A1 | ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME | SFC CO., LTD. (KR) | 2017-08-03 | — | — | US | disclosed |
| US-20170207397-A1 | ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME | SFC CO., LTD. (KR) | 2017-07-20 | — | — | US | disclosed |
| US-9708317-B2 | Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-B]pyrazin-3-one derivatives | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2017-07-18 | — | — | US | disclosed |
| US-20170062729-A1 | HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | SFC CO., LTD. (KR) | 2017-03-02 | — | — | US | disclosed |
| US-20160297814-A1 | PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES | OXY SCIENTIFIC LIMITED (GB) | 2016-10-13 | — | — | US | disclosed |
| EP-3074395-A1 | PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES | Cancer Research Technology Ltd (GB) | 2016-10-05 | — | — | EP | disclosed |
| US-20160285010-A1 | ORGANIC LIGHT EMITTING DISPLAY DEVICE | LG DISPLAY CO., LTD. (KR) | 2016-09-29 | — | — | US | disclosed |
| US-20160204355-A1 | Organic Light-Emitting Diode With High Efficiency And Long Lifetime | SFC CO., LTD. (KR) | 2016-07-14 | — | — | US | disclosed |
| WO-2015075482-A1 | PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170222160-A1 | ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME | ALDH1A2, LAGE3, AOX1 | KDM4E 1340/4885GPR3 3162/4885ALDH1A1 12/4885 |
| US-10100053-B2 | Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-b]pyrazin-3-one derivatives | PAM, PDXK, GRHPR | KDM4E 377/4885GPR3 1544/4885ALDH1A1 1647/4885 |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | BCL6B, BRD7, DBF4 | KDM4E 948/4885GPR3 4535/4885ALDH1A1 3057/4885 |
| US-20170207397-A1 | ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME | HARS1, ALDH1A2, ALDH1A3 | KDM4E 3906/4885GPR3 677/4885ALDH1A1 4/4885 |
| US-20170062729-A1 | HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | DDC, TYR, AOC2 | KDM4E 746/4885GPR3 1873/4885ALDH1A1 208/4885 |
| US-10014479-B2 | Organic light-emitting diode with high efficiency and long lifetime | EML4, CRY2, ESR1 | KDM4E 1586/4885GPR3 4595/4885ALDH1A1 175/4885 |
| US-20170298065-A1 | PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES | TDO2, HPD, PDXK | KDM4E 58/4885GPR3 774/4885ALDH1A1 879/4885 |
| US-20160297814-A1 | PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES | PAM, PDXK, GRHPR | KDM4E 377/4885GPR3 1544/4885ALDH1A1 1647/4885 |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | DDC, TYR, AOC2 | KDM4E 746/4885GPR3 1873/4885ALDH1A1 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.