SCHEMBL17995367

SCHEMBL17995367

CC(F)(F)c1cc(C(F)(F)F)c2nc3c4ccc5c(=O)n6c7cc(C(F)(F)F)cc(C(F)(F)F)c7nc6c6ccc(c(=O)n3c2c1)c4c56

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.34
CACNA1H O95180 3/20 0.33
CACNA1G O43497 2/20 0.33
AHR P35869 1/20 0.33
CAMKK1 Q8N5S9 2/20 0.32
CAMKK2 Q96RR4 2/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
PIM3 Q86V86 1/20 0.32
DYRK2 Q92630 1/20 0.32
MKNK1 Q9BUB5 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
CACNA1B Q00975 2/20 0.32
CYP1A2 P05177 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13260891 0.94 AHR (0.36) BCL2CACNA1HCACNA1GAHRCAMKK1
SCHEMBL13260775 0.94 AHR (0.36) BCL2CACNA1HCACNA1GAHRCAMKK1
SCHEMBL19655409 0.94 BCL2 (0.31) BCL2CACNA1HCACNA1GAHR
SCHEMBL20152215 0.94 BCL2 (0.31) BCL2CACNA1HCACNA1GAHR
SCHEMBL13260885 0.93 AHR (0.36) BCL2CACNA1HCACNA1GAHRCAMKK1
SCHEMBL13260878 0.93 AHR (0.36) BCL2CACNA1HCACNA1GAHRCAMKK1
SCHEMBL26305286 0.93 BCL2 (0.31) BCL2CACNA1HCACNA1GCACNA1C
SCHEMBL23016616 0.91 BCL2 (0.33) BCL2CACNA1HCACNA1GAHRCAMKK1
SCHEMBL19662261 0.87 AHR (0.33) BCL2AHRCAMKK1CAMKK2CYP1A2
SCHEMBL15077797 0.87 ALDH1A1 (0.35) BCL2AHRCAMKK1CAMKK2CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048237-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-23 US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12035614-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035613-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-27 US disclosed
US-20160276603-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-22 US disclosed
US-20160260913-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-08 US disclosed
US-20160260909-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-08 US disclosed
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERAL DISPLAY CORPORATION (US) 2016-09-08 US disclosed
US-20160254457-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-01 US disclosed
US-20160254460-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-01 US disclosed
US-20160240799-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-18 US disclosed
US-20160240800-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-18 US disclosed
US-20160240792-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-18 US disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (20 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, JUND BCL2 1904/4885CACNA1H 1694/4885CACNA1G 1488/4885
US-20160276603-A1 Organic Electroluminescent Materials and Devices EML4, BICRA, TBCB BCL2 3335/4885CACNA1H 1909/4885CACNA1G 1075/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND BCL2 2757/4885CACNA1H 1117/4885CACNA1G 1369/4885
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, SBDS, OCIAD2 BCL2 858/4885CACNA1H 2158/4885CACNA1G 1584/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 BCL2 2213/4885CACNA1H 1769/4885CACNA1G 1523/4885
US-20160254460-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES METTL3, L3MBTL3, CHRM1 BCL2 3698/4885CACNA1H 1616/4885CACNA1G 1309/4885
US-20160240792-A1 Organic Electroluminescent Materials and Devices CBX2, DDX3X, CBX7 BCL2 1822/4885CACNA1H 1276/4885CACNA1G 713/4885
US-20160254457-A1 Organic Electroluminescent Materials and Devices PORCN, MAL2, CYBA BCL2 1783/4885CACNA1H 702/4885CACNA1G 297/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG BCL2 1991/4885CACNA1H 1214/4885CACNA1G 1233/4885
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM BCL2 1231/4885CACNA1H 2955/4885CACNA1G 2698/4885
US-12048237-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP BCL2 2552/4885CACNA1H 1397/4885CACNA1G 1365/4885
US-20160233429-A1 Organic Electroluminescent Materials and Devices NBAS, TBCB, SLC1A2 BCL2 1403/4885CACNA1H 714/4885CACNA1G 369/4885
US-12035614-B2 Organic electroluminescent materials and devices ZFR, SOD1, NDUFS2 BCL2 3220/4885CACNA1H 1209/4885CACNA1G 1346/4885
US-20160240799-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP2 BCL2 1571/4885CACNA1H 1590/4885CACNA1G 1185/4885
US-20160260913-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, TYR, L1CAM BCL2 3505/4885CACNA1H 1314/4885CACNA1G 1319/4885
US-12035613-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC BCL2 3381/4885CACNA1H 1798/4885CACNA1G 1483/4885
US-20160240800-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, TECR, OR10J3 BCL2 1462/4885CACNA1H 1227/4885CACNA1G 1308/4885
US-20160260909-A1 Organic Electroluminescent Materials and Devices PNMT, CYCS, NES BCL2 2966/4885CACNA1H 1081/4885CACNA1G 842/4885
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OCIAD2, OCIAD1 BCL2 1164/4885CACNA1H 1819/4885CACNA1G 1683/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 BCL2 1560/4885CACNA1H 1004/4885CACNA1G 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.