Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Toluene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL7163752 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL28075366 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL27418872 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL27277296 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL2592273 | 1.00 | — | — | |
| Toluene SCHEMBL7591772 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL27372731 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL522792 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL28251042 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL14953876 | 0.96 | ACHE (0.85) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120156140-A | Composite solid wheel and preparation method thereof | 株洲时代新材料科技股份有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-119386649-B | Acid-base washing circulation system for pretreatment of p-chlorotoluene tail gas adsorption equipment | 江苏煌灿科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-116262949-B | Rare earth extractant and method for separating yttrium from heavy rare earth by using rare earth extractant | 厦门稀土材料研究所 | 2025-04-08 | — | — | CN | claimed |
| CN-119661767-A | Divinylbenzene-acryloyl chloride random copolymer, modified aluminum nitride and heat-conducting composite material and preparation method thereof | 西北工业大学 | 2025-03-21 | — | — | CN | claimed |
| CN-117403467-A | Preparation method of bamboo fiber water-repellent breathable paper | 中国制浆造纸研究院有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-220047115-U | Heavy-duty removal tower for toluene chloride production | 安徽海华科技集团有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-220047655-U | Hydrochloric acid absorption tower for toluene chloride production | 安徽海华科技集团有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-114276305-B | Trisubstituted phenyl-1, 2, 4-triazole derivative, preparation method thereof and application thereof in treatment of neuronal injury | 中山大学 | 2023-11-17 | — | — | CN | claimed |
| CN-219771768-U | Aeration type hydrochloric acid recovery system for toluene chloride production | 安徽海华科技集团有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-219518375-U | Hydrochloric acid tail gas absorbing device for producing toluene chloride | 安徽海华科技集团有限公司 | 2023-08-15 | — | — | CN | claimed |
| JP-2012500187-A | — | — | 2012-01-05 | — | — | JP | claimed |
| EP-2310352-A2 | PROCESS FOR PREPARING CINACALCET AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Ind-Swift Laboratories Limited (IN) | 2011-04-20 | — | — | EP | claimed |
| WO-2010004588-A2 | PROCESS FOR PREPARING CINACALCET AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | IND-SWIFT LABORATORIES LIMITED (IN) | 2010-01-14 | — | — | WO | claimed |
| WO-2009034582-A2 | PROCESS FOR THE PREPARATION OF AMORPHOUS FEXOFENADINE HYDROCHLORIDE | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-03-19 | — | — | WO | claimed |
| US-6670472-B2 | Reacting 10-methoxyiminostilbene with cyanic acid (HOCN) in a solvent therefor in the presence of a mild acidic reagent to produce 10-methoxycarbamazepine | MAX INDIA LIMITED (IN) | 2003-12-30 | — | — | US | claimed |
| US-20030105076-A1 | Process for the preparation of 10-methoxycarbamazepine | JUBILANT ORGANOSYS LTD (IN) | 2003-06-05 | — | — | US | claimed |
| EP-1302464-A1 | Process for preparation of 10-methoxycarbamazepine | Max India Limited (IN) | 2003-04-16 | — | — | EP | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| CN-1223992-A | Process for adsorption desulfuration of chlorinated solution of monochlorotoluene | DANYANG CHEM PLANT (CN) | 1999-07-28 | — | — | CN | claimed |