Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Toluene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL7163752 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL28075366 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL27418872 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL27277296 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL7591772 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL180839 | 1.00 | — | — | |
| Toluene SCHEMBL27372731 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL522792 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL28251042 | 1.00 | ACHE (0.92) | — | |
| Toluene SCHEMBL14953876 | 0.96 | ACHE (0.85) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1954 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036385-A | Method for preparing alumina-based ceramic based on 3D printing process | 西北工业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-120192351-A | Preparation method of first-generation Grubbs catalyst | 云南贵金属实验室有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119241817-A | Intrinsic heat-conducting high-molecular polymer, preparation method thereof and heat-conducting polymer composite material | 北京大学深圳研究生院 | 2025-01-03 | — | — | CN | claimed |
| CN-119147512-A | Oxygen sensitive film and preparation method and application thereof | 广州奥松电子股份有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-221673454-U | Benzaldehyde apparatus for producing | 河北深茂新材料科技有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-118077708-A | Corn sheath blight germicide and its preparation and application | 山西农业大学农学院(山西省农业科学院作物科学研究所) | 2024-05-28 | — | — | CN | claimed |
| CN-118027305-A | Polyether-containing polymer, polymer suspending agent, and preparation method and application thereof | 中国石油天然气集团有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117990816-A | Method for determining impurity content in medical intermediate benzyl chloride by using GC | 江苏慈星药业有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117434286-A | Analysis equipment and analysis method for dichlorotoluene isomer | 江苏聚由新材料科技有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-117306245-A | Antibacterial textile material and preparation method thereof | 威海兴海源网具有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-1061667-C | Method for atmospheric prep. of polyarylthio-ether by using industrial sodium sulfide | UNIV SICHUAN UNITED (CN) | 2001-02-07 | — | — | CN | claimed |
| CN-1264715-A | Conjugated/unconjugated copolymer and its preparing process and application | UNIV JILIN (CN) | 2000-08-30 | — | — | CN | claimed |
| CN-1238333-A | Process for preparing dihydroxyl silicate monomer and its polymers | HUANAN SCIENCE & ENGINEERING (CN) | 1999-12-15 | — | — | CN | claimed |
| CN-1230537-A | Preparation process of 2,6-dichloro benzonitrile | CHINA PETROCHEMICAL CORP (CN) | 1999-10-06 | — | — | CN | claimed |
| CN-2327683-Y | Reactor for ammoxidation of halogenated aromatic hydrocarbons | CHINA PETROCHEMICAL GEN CORP (CN) | 1999-07-07 | — | — | CN | claimed |
| CN-1185793-A | Polyarylene sulfide and composition thereof | TONEN SEKIYUKAGAKU KK (JP) | 1998-06-24 | — | — | CN | claimed |
| CN-1145376-A | Method for atmospheric prep. of polyarylthio-ether by using industrial sodium sulfide | UNIV SICHUAN UNITED (CN) | 1997-03-19 | — | — | CN | claimed |
| CN-1029005-C | Method for synthesizing dielectric liquid | ATOCHEM (FR) | 1995-06-21 | — | — | CN | claimed |
| CN-1080279-A | 2, the preparation of 4-toluene dichloride | SHENYANG CHEMICAL INST MINISTR (CN) | 1994-01-05 | — | — | CN | claimed |
| CN-1050894-A | The preparation method of the synthesis of dielectric fluids | ATOCHEM (FR) | 1991-04-24 | — | — | CN | claimed |