Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL5519550 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL28637632 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL7257269 | 1.00 | — | — | |
| Imidazole SCHEMBL14940880 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL2073378 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL156533 | 1.00 | — | — | |
| Imidazole SCHEMBL23140246 | 0.97 | — | — | |
| Imidazole SCHEMBL5940577 | 0.97 | — | — | |
| Imidazole SCHEMBL11803881 | 0.97 | — | — | |
| Imidazole SCHEMBL9161416 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978436-B | High-efficiency and low-consumption reverse suspension polymerization preparation process of water-absorbing compound | 万华化学集团股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-114349892-A | Anti-caking water-absorbent resin and preparation method thereof | 万华化学集团股份有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-111978436-A | High-efficiency and low-consumption reverse suspension polymerization preparation process of water-absorbing compound | 万华化学集团股份有限公司 | 2020-11-24 | — | — | CN | claimed |
| CN-103096717-A | Fungicidal combinations of dithiin-tetracarboxamide derivatives with microorganisms or isoflavones | BAYER IP GMBH | 2013-05-08 | — | — | CN | claimed |
| US-20250032455-A1 | NITROIMIDAZOLE FORMULATIONS | IRP Health Pty Ltd (AU) | 2025-01-30 | — | — | US | disclosed |
| US-12171748-B2 | Nitroimidazole formulations | IRP Health Pty Ltd (AU) | 2024-12-24 | — | — | US | disclosed |
| CN-119146785-A | Thermal diode, glass curtain wall and application thereof | 香港科技大学(广州) | 2024-12-17 | — | — | CN | disclosed |
| CN-117321050-A | Modified inhibitors of membrane iron transport proteins | 威佛（国际）股份公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-116323572-A | 3- (2- (benzo [ D ] thiazol-2-yl) -2- (phenylsulfonylamino) ethyl) benzamide derivatives and related compounds as TMPRSS2 inhibitors for the treatment of viral infections | 塔斯宾医疗公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4139291-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-111978436-B | High-efficiency and low-consumption reverse suspension polymerization preparation process of water-absorbing compound | 万华化学集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |
| US-5948912-A | THERAPY FOR PSYCHOLOGICAL, NERVOUS SYSTEM DISORDERS | NEUROGEN CORPORATION (US) | 1999-09-07 | — | — | US | disclosed |
| US-5789410-A | TREATMENT OF SCHIZOPHRENIA, DEPRESSION, PARKINSON'S DISEASE | NEUROGEN CORPORATION (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0796866-A1 | Antithrombotic diamides | ELI LILLY AND COMPANY (US) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996016057-A1 | CERTAIN 1-SUBSTITUTED AMINOMETHYL IMIDAZOLE AND PYRROLE DERIVATIVES; NOVEL DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1996-05-30 | — | — | WO | disclosed |
| CN-1098745-A | Method with PQQ-dependent dehydrogenase colorimetric estimation analyte | BOEHRINGER MANNHEIM GMBH (DE) | 1995-02-15 | — | — | CN | disclosed |
| CN-1026063-C | Pharmaceutical composition containing substituted thiopheno derivatives | HOECHST AG (DE) | 1994-10-05 | — | — | CN | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |