Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL5519550 | 1.00 | ALDH1A1 (0.93) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL7257269 | 1.00 | — | — | |
| Imidazole SCHEMBL14940880 | 1.00 | ALDH1A1 (0.93) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL2073378 | 1.00 | ALDH1A1 (0.93) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL156533 | 1.00 | — | — | |
| Imidazole SCHEMBL2073380 | 1.00 | — | — | |
| Imidazole SCHEMBL23140246 | 0.97 | — | — | |
| Imidazole SCHEMBL5940577 | 0.97 | — | — | |
| Imidazole SCHEMBL11803881 | 0.97 | — | — | |
| Imidazole SCHEMBL9161416 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957288-B | Synthesis method of tetramisole hydrochloride | 苏州华道生物药业股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-114920760-A | Racemization method of dextro-tetramisole | 苏州华道生物药业股份有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-113403305-A | DNA separated or purified from human peripheral blood red blood cell and its preparing method and use | 博尔诚（北京）科技有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-118852050-B | Novel levamisole intermediate compound and preparation method and application thereof | 烟台药物研究所 | 2025-05-13 | — | — | CN | disclosed |
| CN-119410628-A | Enhanced erythrocyte lysate, erythrocyte DNA extraction kit and method | 武汉大学中南医院 | 2025-02-11 | — | — | CN | disclosed |
| CN-119285523-A | Method for recovering tetramisole hydrochloride resolving agent N-p-toluenesulfonyl-L-proline | 河北尚澳生物科技有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119285654-A | Resolution method of tetramisole hydrochloride | 河北尚澳生物科技有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-118852050-A | Novel levamisole intermediate compound and preparation method and application thereof | 烟台药物研究所 | 2024-10-29 | — | — | CN | disclosed |
| CN-117800881-A | Recovery method of levamisole hydrochloride resolving agent N-p-toluenesulfonyl-L- (+) -glutamic acid | 常州齐晖药业有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-114920760-B | Racemization method of dextetramidazole | 苏州华道生物药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-114957288-B | Synthesis method of tetramisole hydrochloride | 苏州华道生物药业股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117466916-A | Method for splitting tetramisole hydrochloride | 上海工程技术大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-220276974-U | Reaction device for preparing tetramidazole hydrochloride intermediate | 宁夏华昊生物科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-220169776-U | Drying system applied to tetramisole hydrochloride | 宁夏华昊生物科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-220003994-U | Tubular reactor for preparing tetramisole hydrochloride intermediate | 宁夏华昊生物科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-116507327-A | Chewable formulations | 礼蓝动物保健有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-115927291-A | DNA separated or purified from human peripheral blood red blood cell and its preparing method and use | 博尔诚（北京）科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114307991-A | Preparation of chiral separation column for resolution of tetramisole | 宁夏华昊生物科技有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-113403305-B | DNA separated or purified from human peripheral blood red blood cell and its preparing method and use | 博尔诚（北京）科技有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-113403305-A | DNA separated or purified from human peripheral blood red blood cell and its preparing method and use | 博尔诚（北京）科技有限公司 | 2021-09-17 | — | — | CN | disclosed |