Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.48 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28906318 | 1.00 | FAAH (0.48) | FAAHSOAT1SOAT2CES1DAGLA | |
| SCHEMBL6361012 | 0.99 | FAAH (0.49) | FAAHSOAT1SOAT2CES1DAGLA | |
| Hydrochloric Acid SCHEMBL5907691 | 0.92 | ALDH1A1 (0.45) | CES1KDM4EMEN1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL11789024 | 0.92 | ALDH1A1 (0.45) | CES1KDM4EMEN1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL4883901 | 0.92 | ALDH1A1 (0.45) | CES1KDM4EMEN1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL11786500 | 0.92 | ALDH1A1 (0.45) | CES1KDM4EMEN1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL11789419 | 0.92 | ALDH1A1 (0.45) | CES1KDM4EMEN1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL11783864 | 0.92 | ALDH1A1 (0.45) | CES1KDM4EMEN1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL11796321 | 0.92 | ALDH1A1 (0.45) | CES1KDM4EMEN1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL11793086 | 0.92 | ALDH1A1 (0.45) | CES1KDM4EMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105086-B1 | A COMPOSITION FOR LIGHTENING AND HIGHLIGHTING HAIR | UNILEVER PLC (GB) | 2004-06-16 | — | — | EP | claimed |
| US-20020076388-A1 | Composition for lightening and highlighting hair | HELENE CURTIS, INC. | 2002-06-20 | — | — | US | claimed |
| US-6274126-B1 | FOR BLEACHING HAIR | HELENE CURTIS, INC. | 2001-08-14 | — | — | US | claimed |
| EP-1105086-A1 | A COMPOSITION FOR LIGHTENING AND HIGHLIGHTING HAIR | UNILEVER PLC (GB) | 2001-06-13 | — | — | EP | claimed |
| WO-2000010515-A1 | A COMPOSITION FOR LIGHTENING AND HIGHLIGHTING HAIR | UNILEVER PLC (GB) | 2000-03-02 | — | — | WO | claimed |
| US-5833965-A | DEODORIZING GELS OR SOLIDS COMPRISING A BORATE AS CROSSLINKER INTERACT WITH THE ANTIPERSPIRANT COMPOUND TO INCREASE THE FIRMNESS AND CLARITY, TRANSPARENCIES | HELENE CURTIS, INC. (US) | 1998-11-10 | — | — | US | claimed |
| US-5547661-A | MIXTURE WITH A CROSSLINKER, SURFACTANT AND CARRIER | HELENE CURTIS, INC. (US) | 1996-08-20 | — | — | US | claimed |
| US-4035478-A | VINYLPYRROLIDONE, DIMETHYLAMINOETHYL METHACRYLATE | AMERICAN CYANAMID COMPANY (US) | 1977-07-12 | — | — | US | claimed |
| US-20250066992-A1 | FIBERS FOR HAIR, METHOD FOR PRODUCING SAME, FIBER TREATMENT AGENT AND HAIR ACCESSORY | DENKA COMPANY LIMITED (JP) | 2025-02-27 | — | — | US | disclosed |
| CN-119096319-A | Energy storage device | 快帽系统公司 | 2024-12-06 | — | — | CN | disclosed |
| EP-4424612-A1 | DRY SHAMPOO SPRAY FOAM TECHNOLOGY | Henkel AG & Co. KGaA (DE) | 2024-09-04 | — | — | EP | disclosed |
| US-20240285483-A1 | Dry Shampoo Spray Foam Technology | HENKEL AG & CO KGAA (DE) | 2024-08-29 | — | — | US | disclosed |
| WO-2023199690-A1 | FIBER FOR ARTIFICIAL HAIR AND HEADDRESS PRODUCT | デンカ株式会社 | 2023-10-19 | — | — | WO | disclosed |
| WO-2023127456-A1 | FIBERS FOR HAIR, METHOD FOR PRODUCING SAME, FIBER TREATMENT AGENT AND HAIR ACCESSORY | デンカ株式会社 | 2023-07-06 | — | — | WO | disclosed |
| US-4976956-A | Water soluble and oil soluble quaternary ammonium compounds and amidoamine | HELENE CURTIS, INC. (US) | 1990-12-11 | — | — | US | disclosed |
| US-4777037-A | IMPROVED COMBING AND FEEL | HELENE CURTIS INDUSTRIES, INC. (US) | 1988-10-11 | — | — | US | disclosed |
| US-4311517-A | ERWINIA, PSEUDOMONAS, QUATERNARY AMMONIUM SURFACTANT | SHELL OIL COMPANY (US) | 1982-01-19 | — | — | US | disclosed |
| US-4284434-A | Process for spray cleaning of metal surfaces | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1981-08-18 | — | — | US | disclosed |
| US-4035478-A | VINYLPYRROLIDONE, DIMETHYLAMINOETHYL METHACRYLATE | AMERICAN CYANAMID COMPANY (US) | 1977-07-12 | — | — | US | disclosed |
| US-3932224-A | Method of preventing scale from being deposited in case of producing fresh water from sea water | KEISHIN MATSUMOTO DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JA) | 1976-01-13 | — | — | US | disclosed |